Plasmid Engineering for Controlled and Sustained Gene Expression for Nonviral Gene Therapy Ethlinn V. B. van GaalWim E. HenninkEnrico Mastrobattista Expert Review 26 May 2006 Pages: 1053 - 1074
Metabonomics Techniques and Applications to Pharmaceutical Research & Development John C. LindonElaine HolmesJeremy K. Nicholson Expert Review 25 May 2006 Pages: 1075 - 1088
CYP Induction-Mediated Drug Interactions: in Vitro Assessment and Clinical Implications Jiunn H. Lin Expert Review 26 May 2006 Pages: 1089 - 1116
Testosterone Hormone Replacement Therapy: State-of-the-Art and Emerging Technologies Marie-Laure LeichtnamHervé RollandRichard H. Guy Expert Review 09 June 2006 Pages: 1117 - 1132
Effects of Antipsychotic Drugs on Ito, INa, Isus, IK1, and hERG: QT Prolongation, Structure Activity Relationship, and Network Analysis William J. Crumb Jr.Sean EkinsCharles M. Beasley Jr. Feature Article 25 May 2006 Pages: 1133 - 1143
Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test Ryusuke TakanoKiyohiko SuganoShinji Yamashita Research Paper 25 May 2006 Pages: 1144 - 1156
Adaptive Neuro-Fuzzy Modeling of Poorly Soluble Drug Formulations Dionysios DouroumisLeontios J. HadjileontiadisAlfred Fahr Research Paper 25 May 2006 Pages: 1157 - 1164
Saturable Absorptive Transport of the Hydrophilic Organic Cation Ranitidine in Caco-2 Cells: Role of pH-Dependent Organic Cation Uptake System and P-Glycoprotein David L. BourdetDhiren R. Thakker Research Paper 08 June 2006 Pages: 1165 - 1177
Intestinal Absorptive Transport of the Hydrophilic Cation Ranitidine: A Kinetic Modeling Approach to Elucidate the Role of Uptake and Efflux Transporters and Paracellular vs. Transcellular Transport in Caco-2 Cells David L. BourdetGary M. PollackDhiren R. Thakker Research Paper 08 June 2006 Pages: 1178 - 1187
Hepatic CYP3A Expression is Attenuated in Obese Mice Fed a High-Fat Diet Kouichi YoshinariShunsuke TakagiMasao Miwa Research Paper 25 May 2006 Pages: 1188 - 1200
Characteristics of Substance P Transport Across the Blood–Brain Barrier Arvind K. ChappaKenneth L. AudusSusan M. Lunte Research Paper 01 June 2006 Pages: 1201 - 1208
Interaction of Ibuprofen and Other Structurally Related NSAIDs with the Sodium-Coupled Monocarboxylate Transporter SMCT1 (SLC5A8) Shirou ItagakiElangovan GopalVadivel Ganapathy Research Paper 01 June 2006 Pages: 1209 - 1216
Nasal Immunization with Anthrax Protective Antigen Protein Adjuvanted with Polyriboinosinic–Polyribocytidylic Acid Induced Strong Mucosal and Systemic Immunities Brian R. SloatZhengrong Cui Research Paper 25 May 2006 Pages: 1217 - 1226
Glucose Partition Coefficient and Diffusivity in the Lower Skin Layers Enam KhalilKosmas KretsosGerald B. Kasting Research Paper 26 May 2006 Pages: 1227 - 1234
ATP-Binding Cassette Transporter G2 Mediates the Efflux of Phototoxins on the Luminal Membrane of Retinal Capillary Endothelial Cells Tomoko AsashimaSatoko HoriTetsuya Terasaki Research Paper 25 May 2006 Pages: 1235 - 1242
Enhanced Oral Paclitaxel Bioavailability After Administration of Paclitaxel-Loaded Lipid Nanocapsules Sandra PeltierJean-Michel OgerJean-Pierre Benoît Research Paper 25 May 2006 Pages: 1243 - 1250
A Specific Picomolar Hybridization-Based ELISA Assay for the Determination of Phosphorothioate Oligonucleotides in Plasma and Cellular Matrices Xiaohui WeiGuowei DaiKenneth K. Chan Research Paper 25 May 2006 Pages: 1251 - 1264
Nontoxic Suramin as a Chemosensitizer in Patients: Dosing Nomogram Development Danny ChenSae Heum SongJessie L-S. Au Research Paper 25 May 2006 Pages: 1265 - 1274
Rationale for Fixed Dosing of Pertuzumab in Cancer Patients Based on Population Pharmacokinetic Analysis Chee M. NgBert L. LumDavid Allison Research Paper 26 May 2006 Pages: 1275 - 1284
Gd-DTPA l-Cystine Bisamide Copolymers as Novel Biodegradable Macromolecular Contrast Agents for MR Blood Pool Imaging Todd L. KaneshiroTianyi KeZheng-Rong Lu Research Paper 01 June 2006 Pages: 1285 - 1294
The Influence of Surfactant on PLGA Microsphere Glass Transition and Water Sorption: Remodeling the Surface Morphology to Attenuate the Burst Release C. BouissouJ. J. RouseC. F. van der Walle Research Paper 25 May 2006 Pages: 1295 - 1305
Hydrolytic Degradation and Drug Release of Ricinoleic Acid–Lactic Acid Copolyesters Raia SlivniakAviva EzraAbraham J. Domb Research Paper 08 June 2006 Pages: 1306 - 1312
Complement Activation by Core–Shell Poly(isobutylcyanoacrylate)–Polysaccharide Nanoparticles: Influences of Surface Morphology, Length, and Type of Polysaccharide Isabelle BertholonChristine VauthierDenis Labarre Research Paper 25 May 2006 Pages: 1313 - 1323
Expression of Basic Fibroblast Growth Factor Correlates with Resistance to Paclitaxel in Human Patient Tumors Yuebo GanM. Guillaume WientjesJessie L.-S. Au Research Paper 08 June 2006 Pages: 1324 - 1331
Reverse Hexagonal Phase Nanodispersion of Monoolein and Oleic Acid for Topical Delivery of Peptides: in Vitro and in Vivo Skin Penetration of Cyclosporin A Luciana B. LopesDenise A. FerreiraM. Vitória L. B. Bentley Research Paper 25 May 2006 Pages: 1332 - 1342
Electron Beam and Gamma Radiolysis of Solid-State Metoclopramide Aubert MaquilleCatherine SlegersBernard Tilquin Research Paper 08 June 2006 Pages: 1343 - 1349
FTIR and nDSC as Analytical Tools for High-Concentration Protein Formulations Susanne MatheusWolfgang FriessHanns-Christian Mahler Research Paper 26 May 2006 Pages: 1350 - 1363
Effect of Oropharyngeal Length in Drug Lung Delivery via Suspension Pressurized Metered Dose Inhalers T. EhtezaziD. R. AllansonC. O'Callaghan Research Paper 26 May 2006 Pages: 1364 - 1372
Canine Intestinal Contents vs. Simulated Media for the Assessment of Solubility of Two Weak Bases in the Human Small Intestinal Contents Lida KalantziEva PerssonChristos Reppas Research Paper 25 May 2006 Pages: 1373 - 1381
Protein Structural Conformation and Not Second Virial Coefficient Relates to Long-Term Irreversible Aggregation of a Monoclonal Antibody and Ovalbumin in Solution Harminder BajajVikas K. SharmaDevendra S. Kalonia Research Paper 25 May 2006 Pages: 1382 - 1394
Design and Evaluation of Celecoxib Porous Particles using Melt Sonocrystallization Anant ParadkarManish MaheshwariPeter York Research Paper 07 June 2006 Pages: 1395 - 1400