1. Quantitative Structure–Activity Relationship and Quantitative Structure–Pharmacokinetics Relationship of 1,4-Dihydropyridines and Pyridines as Multidrug Resistance Modulators

   • Xiao-Fei Zhou
   • Qingxiang Shao
   • Marilyn E. Morris

   Research Paper 20 September 2005 Pages: 1989 - 1996

   

2. Structural Characterization and Immunogenicity in Wild-Type and Immune Tolerant Mice of Degraded Recombinant Human Interferon Alpha2b

   • Suzanne Hermeling
   • Liliana Aranha
   • Wim Jiskoot

   Research Paper 03 October 2005 Pages: 1997 - 2006

   

3. Activity and Expression of Various Isoforms of Uridine Diphosphate Glucuronosyltransferase are Differentially Regulated During Hepatic Regeneration in Rats

   • Hui Tian
   • Junhai Ou
   • Raman Venkataramanan

   Research Paper 21 October 2005 Pages: 2007 - 2015

   

4. Pharmacokinetic Significance of Renal OAT3 (SLC22A8) for Anionic Drug Elimination in Patients with Mesangial Proliferative Glomerulonephritis

   • Yuji Sakurai
   • Hideyuki Motohashi
   • Ken-ichi Inui

   Research Paper 01 November 2005 Pages: 2016 - 2022

   

5. BCRP Transports Dipyridamole and is Inhibited by Calcium Channel Blockers

   • Yi Zhang
   • Anshul Gupta
   • Qingcheng Mao

   Research Paper 01 November 2005 Pages: 2023 - 2034

   

6. Pharmacokinetic and Pharmacodynamic Evaluations of the Zwitterionic Metabolite of a New Series of N-Substituted Soft Anticholinergics

   • Whei-Mei Wu
   • Peter Buchwald
   • Nicholas Bodor

   Research Paper 26 September 2005 Pages: 2035 - 2044

   

7. In Vitro Evaluation of Various Buccal Permeation Enhancing Systems for PACAP (Pituitary Adenylate Cyclase-Activating Polypeptide)

   • Nina Langoth
   • Andreas Bernkop-Schnürch
   • Peter Kurka

   Research Paper 02 September 2005 Pages: 2045 - 2050

   

8. Development of Stealth Liposome Formulation of 2′-Deoxyinosine as 5-Fluorouracil Modulator: In Vitro and In Vivo Study

   • Raphaelle Fanciullino
   • Sarah Giacometti
   • Joseph Ciccolini

   Research Paper 21 October 2005 Pages: 2051 - 2057

   

9. Uptake and Transport of PEG-Graft-Trimethyl-Chitosan Copolymer–Insulin Nanocomplexes by Epithelial Cells

   • Shirui Mao
   • Oliver Germershaus
   • Thomas Kissel

   Research Paper 26 September 2005 Pages: 2058 - 2068

   

10. Effect of Charge and Molecular Weight on Transdermal Peptide Delivery by Iontophoresis

    • Nada Abla
    • Aarti Naik
    • Yogeshvar N. Kalia

    Research Paper 26 September 2005 Pages: 2069 - 2078

    

11. Self-Assembled Biodegradable Nanoparticles Developed by Direct Dialysis for the Delivery of Paclitaxel

    • Jingwei Xie
    • Chi-Hwa Wang

    Research Paper 03 September 2005 Pages: 2079 - 2090

    

12. Sequence-Specific Suppression of mdr1a/1b Expression in Mice via RNA Interference

    • Yumi Matsui
    • Naoki Kobayashi
    • Yoshinobu Takakura

    Research Paper 01 October 2005 Pages: 2091 - 2098

    

13. Tat-Conjugated PAMAM Dendrimers as Delivery Agents for Antisense and siRNA Oligonucleotides

    • Hyunmin Kang
    • Robert DeLong
    • Rudolph L. Juliano

    Research Paper 01 October 2005 Pages: 2099 - 2106

    

14. Poly(Ethylene Oxide)-Modified Poly(β-Amino Ester) Nanoparticles as a pH-Sensitive System for Tumor-Targeted Delivery of Hydrophobic Drugs: Part 2. In Vivo Distribution and Tumor Localization Studies

    • Dinesh Shenoy
    • Steven Little
    • Mansoor Amiji

    Research Paper 03 November 2005 Pages: 2107 - 2114

    

15. ATP-Loaded Liposomes Effectively Protect the Myocardium in Rabbits with an Acute Experimental Myocardial Infarction

    • Daya D. Verma
    • William C. Hartner
    • Vladimir P. Torchilin

    Research Paper 05 November 2005 Pages: 2115 - 2120

    

16. The Role of Molecular Structure in the Crystal Polymorphism of Local Anesthetic Drugs: Crystal Polymorphism of Local Anesthetic Drugs, Part X

    • Andrea C. Schmidt

    Research Paper 16 November 2005 Pages: 2121 - 2133

    

17. Viscoelastic Properties of Carbopol 940 Gels and Their Relationships to Piroxicam Diffusion Coefficients in Gel Bases

    • Rathapon A-sasutjarit
    • Anuvat Sirivat
    • Panida Vayumhasuwan

    Research Paper 14 October 2005 Pages: 2134 - 2140

    

18. The Effects of Food on the Dissolution of Poorly Soluble Drugs in Human and in Model Small Intestinal Fluids

    • Eva M. Persson
    • Ann-Sofie Gustafsson
    • Bertil Abrahamsson

    Research Paper 30 October 2005 Pages: 2141 - 2151

    

19. Comparison of Diafiltration and Tangential Flow Filtration for Purification of Nanoparticle Suspensions

    • Gautam Dalwadi
    • Heather A. E. Benson
    • Yan Chen

    Research Paper 15 September 2005 Pages: 2152 - 2162

    

20. Cubosome Dispersions as Delivery Systems for Percutaneous Administration of Indomethacin

    • Elisabetta Esposito
    • Rita Cortesi
    • Carmelo Puglia

    Research Paper 08 November 2005 Pages: 2163 - 2173

    

21. AAPS Update

    OriginalPaper 16 December 2005 Pages: 2174 - 2175

22. Author Index to Volume 22 (2005)

    OriginalPaper 01 November 2005 Pages: 2176 - 2179

23. Subject Index to Volume 22

    OriginalPaper 01 November 2005 Pages: 2180 - 2184