Influence of the Structure of Drug Moieties on the in Vitro Efficacy of HPMA Copolymer–Geldanamycin Derivative Conjugates Yuji KasuyaZheng-Rong LuJindřich Kopeček OriginalPaper Pages: 115 - 123
HPLC Determination of Binding of Cisplatin to DNA in the Presence of Biological Thiols: Implications of Dominant Platinum-Thiol Binding to Its Anticancer Action Erika VolckovaLea P. DudonesRathindra N. Bose OriginalPaper Pages: 124 - 131
Size-Dependency of DL-Lactide/Glycolide Copolymer Particulates for Intra-Articular Delivery System on Phagocytosis in Rat Synovium Eijiro HorisawaKatsuaki KubotaYoshiaki Kawashima OriginalPaper Pages: 132 - 139
Intracellular Processing of Poly(Ethylene Imine)/Ribozyme Complexes Can Be Observed in Living Cells by Using Confocal Laser Scanning Microscopy and Inhibitor Experiments Thomas MerdanKlaus KunathThomas Kissel OriginalPaper Pages: 140 - 146
Comparative Inhibitory Effects of Different Compounds on Rat Oatp1 (Slc21a1)- and Oatp2 (Slc21a5)-Mediated Transport Yoshihisa ShitaraDaisuke SugiyamaYuichi Sugiyama OriginalPaper Pages: 147 - 153
Proton Gradient-Dependent Transport of Valproic Acid in Human Placental Brush-Border Membrane Vesicles Hiroaki NakamuraFumihiko UshigomeYasufumi Sawada OriginalPaper Pages: 154 - 161
Permeability Profiles of M-Alkoxysubstituted Pyrrolidinoethylesters of Phenylcarbamic Acid Across Caco-2 Monolayers and Human Skin Lenka GyürösiováLeena LaitinenJouni Hirvonen OriginalPaper Pages: 162 - 168
The Potential of Chitosan in Enhancing Peptide and Protein Absorption Across the TR146 Cell Culture Model—An in Vitro Model of the Buccal Epithelium Ana PorteroCarmen Remuñán-LópezHanne Mørck Nielsen OriginalPaper Pages: 169 - 174
Peptide Acylation by Poly(α-Hydroxy Esters) Andrea LuckeJosef KiermaierAchim Göpferich OriginalPaper Pages: 175 - 181
Experimental and Computational Screening Models for Prediction of Aqueous Drug Solubility Christel A. S. BergströmUlf NorinderPer Artursson OriginalPaper Pages: 182 - 188
Production and Characterization of a Budesonide Nanosuspension for Pulmonary Administration Claudia JacobsRainer Helmut Müller OriginalPaper Pages: 189 - 194
Thermophysical Properties of Pharmaceutically Compatible Buffers at Sub-Zero Temperatures: Implications for Freeze-Drying Evgenyi Y. ShalaevTiffany D. Johnson-EltonMichael J. Pikal OriginalPaper Pages: 195 - 201
Effect of Testosterone Suppression on the Pharmacokinetics of a Potent GnRH Receptor Antagonist Eugenia A. IatsimirskaiaMargaret L. GregoryJohn M. May OriginalPaper Pages: 202 - 208
Ignoring Pharmacokinetics May Lead to Isoboles Misinterpretation: Illustration with the Norfloxacin-Theophylline Convulsant Interaction in Rats Miren CadartSandrine MarchandWilliam Couet OriginalPaper Pages: 209 - 214