Optimizing the Science of Drug Development: Opportunities for Better Candidate Selection and Accelerated Evaluation in Humans Lawrence J LeskoMalcolm RowlandTerrence F Blaschke OriginalPaper Pages: 1335 - 1344
Protein Kinases as Therapeutic Targets Rajagopalan SridharOlivia Hanson-PaintonDenise R. Cooper OriginalPaper Pages: 1345 - 1353
Synergistic Effect of Enhancers for Transdermal Drug Delivery Samir Mitragotri ReviewPaper Pages: 1354 - 1359
Generation of Micro-Particles of Proteins for Aerosol Delivery Using High Pressure Modified Carbon Dioxide Rana T BustamiHak-Kim ChanNeil R Foster OriginalPaper Pages: 1360 - 1366
Formation and Isolation of Spherical Fine Protein Microparticles Through Lyophilization of Protein-Poly(ethylene Glycol) Aqueous Mixture Takahiro MoritaYuji HorikiriHiroyuki Yoshino OriginalPaper Pages: 1367 - 1373
Protein Spray-Freeze Drying. Effect of Atomization Conditions on Particle Size and Stability Henry R CostantinoLaleh FirouzabadianMark A Tracy OriginalPaper Pages: 1374 - 1382
Use of Artificial Neural Networks to Predict Drug Dissolution Profiles and Evaluation of Network Performance Using Similarity Factor Kok Khiang PehChee Peng LimKean Hock Khoh OriginalPaper Pages: 1384 - 1389
An Increased Throughput Method for the Determination of Partition Coefficients Laure HitzelAlan P WattKaren L Locker OriginalPaper Pages: 1389 - 1395
Application of High Performance Liquid Chromatography Coupled with Ultraviolet Spectroscopy and Electrospray Mass Spectrometry to the Characterisation of Ellagitannins From Terminalia Macroptera Roots Olga SilvaElsa T GomesKurt Hostettmann OriginalPaper Pages: 1396 - 1401
Dextran-Methylprednisolone Succinate as a Prodrug of Methylprednisolone: Immunosuppressive Effects After In Vivo Administration to Rats Reza MehvarDean A Hoganson OriginalPaper Pages: 1402 - 1407
In Vivo Study of the Effect of Valpromide and Valnoctamide in the Pilocarpine Rat Model of Focal Epilepsy Hilde LindekensIlse SmoldersYvette Michotte OriginalPaper Pages: 1408 - 1413
Does Epidermal Turnover Reduce Percutaneous Penetration? Micaela B ReddyRichard H GuyAnnette L Bunge OriginalPaper Pages: 1414 - 1419
The in Vitro Cell Association of Invasin Coated Polylactide-Co-glycolide Nanoparticles Gordon F DawsonGavin W Halbert OriginalPaper Pages: 1420 - 1425
Absorption and Disposition of a Selective Aldosterone Receptor Antagonist, Eplerenone, in the Dog Chyung S CookLiming ZhangJuDee S Fischer OriginalPaper Pages: 1426 - 1431
The Role of Metabolites in Bioequivalency Assessment. III. Highly Variable Drugs with Linear Kinetics and First-Pass Effect Andre J Jackson OriginalPaper Pages: 1432 - 1436
Physical Characterization of Large Porous Particles for Inhalation Rajiv GuptaR VanbeverDA Edwards OriginalPaper Pages: 1437 - 1438
Book Reviews. Particle-Lung Infections, Lung Biology in Health and Disease Series, Volume 143. Peter Gehr and Joachim Heyder, Eds. Marcel Dekker, Inc., 270 Madison Avenue, New York, NY 1006-0602, http://www.dekker.com, 2000. xxi, 802 pp., illustrations. $225.00. Design and Analysis of Bioavailability and Bioequivalence Studies, Second Edition Revised and Expanded. Shein-Chung Chow and Jen-Pei Liu, Eds. Marcel Dekker, Inc., 270 Madison Avenue, New York, NY 1006-0602, 1999. 584 pp., illustrations. $195.00. Supervised and Unsupervised Pattern Recognition. Feature Extraction and Computational Intelligence. Evangelia Micheli-Tzanakou. CRC Press LLC., 2000 Corporate Blvd., N.W., Boca Raton, FL 33431, 2000. xxii, 371 pp., illustrations. $99.95. Vaccine Adjuvants. Preparation Methods and Research Protocols.Derek T. O'Hagan, Ed. Humana Press, 999 Riverview Drive, Suite 208, Totowa, NJ 07512, http://www.humanapress.com, 2000. x, 342 pp., illustrations. $99.50. Solid-State Chemistry of Drugs, Second Edition.Stephen R. Byrn, Ralph R. Pfeiffer, and Joseph G. Stowell, Eds. SSCI, Inc., 3065 Kent Avenue, West Lafayette, IN 47906-1076, http://ssci-inc.com 1999. xvii, 574 pp., illustrations. $165.00. Anthony HickeyAjaz S HussainKinam Park OriginalPaper Pages: 1439 - 1442