An Interview with a Distinguished Pharmaceutical Scientist: George Zografi To whom correspondence should be addressed at University of Wisconsin—Madison, 425 N. Charter Street, Madison, Wisconsin 53706. George Zografi Legacy Pages: 973 - 975
Phase Behavioral Effects on Particle Formation Processes Using Supercritical Fluids Srinivas PalakodatyPeter York ReviewPaper Pages: 976 - 985
Comparison of the Anticancer Effect of Free and HPMA Copolymer-Bound Adriamycin in Human Ovarian Carcinoma Cells Tamara MinkoPavla KopečkováJindřich Kopeček OriginalPaper Pages: 986 - 996
A Novel Podophyllotoxin-Derived Compound GL331 Is More Potent than Its Congener VP-16 in Killing Refractory Cancer Cells Tze-Sing HuangChun-Chung LeeJacqueline Whang-Peng OriginalPaper Pages: 997 - 1002
Pharmacokinetic Features and Metabolism of Calphostin C, A Naturally Occurring Perylenequinone with Antileukemic Activity Chun-Lin ChenHung-Liang TaiFatih M. Uckun OriginalPaper Pages: 1003 - 1009
Biorecognition of HPMA Copolymer-Adriamycin Conjugates by Lymphocytes Mediated by Synthetic Receptor Binding Epitopes Vladimir OmelyanenkoPavla KopečkováJindřich Kopeček OriginalPaper Pages: 1010 - 1019
Intracellular Compartmentalization of DNA Fragments in Cultured Airway Epithelial Cells Mediated by Cationic Lipids Adam R. HolmesAustin F. DohrmanDieter C. Gruenert OriginalPaper Pages: 1020 - 1025
Structural Requirements for Alkylglycoside-Type Renal Targeting Vector Kokichi SuzukiTakashi AndoYuichi Sugiyama OriginalPaper Pages: 1026 - 1034
Inhibition of Intestinal Metabolism of the Antiviral Ester Prodrug bis(POC)-PMPA by Nature-Identical Fruit Extracts as a Strategy to Enhance Its Oral Absorption: An In Vitro Study Jan Van GelderPieter AnnaertPatrick Augustijns OriginalPaper Pages: 1035 - 1040
Development of Anti-Influenza Virus Drugs I: Improvement of Oral Absorption and In Vivo Anti-Influenza Activity of Stachyflin and Its Derivatives Shigenori YagiJunko OnoNaofumi Hashimoto OriginalPaper Pages: 1041 - 1046
Lipophilization of Somatostatin Analog RC-160 Improves Its Bioactivity and Stability P. DasguptaA. T. SinghR. Mukherjee OriginalPaper Pages: 1047 - 1053
Thermodynamic In Vitro Studies as a Method to Investigate the Pharmacodynamic Behavior of Adenosine A1 Receptor Ligands Alessandro DalpiazAngelo ScatturinPier Andrea Borea OriginalPaper Pages: 1054 - 1058
Anti-GAD Monoclonal Antibody Delays the Onset of Diabetes Mellitus in NOD Mice Virginie MenardHarvey JacobsSung Wan Kim OriginalPaper Pages: 1059 - 1066
Cyclosporine Transfer from Low- and High-Density Lipoproteins Is Partially Influenced by Lipid Transfer Protein I Triglyceride Transfer Activity Kishor M. WasanRamaswamy SubramanianP. Haydn Pritchard OriginalPaper Pages: 1067 - 1073
Carbomer Inhibits Tryptic Proteolysis of Luteinizing Hormone-Releasing Hormone and N-α-Benzoyl-L-Arginine Ethyl Ester by Binding the Enzyme Greg F. WalkerRobin LedgerIan G. Tucker OriginalPaper Pages: 1074 - 1080
Glucuronidation Kinetics of R,S-Ketoprofen in Adjuvant-Induced Arthritic Rats Christine J. MeunierRoger K. Verbeeck OriginalPaper Pages: 1081 - 1086
Regional Differences in Quinine Absorption from the Undisturbed Human Colon Assessed Using a Timed Release Delivery System John M. HebdenClive G. WilsonAlan C. Perkins OriginalPaper Pages: 1087 - 1092
Improved Lipid Lowering Activity of Bezafibrate Following Continuous Gastrointestinal Administration: Pharmacodynamic Rationale for Sustained Release Preparation of the Drug Amnon HoffmanYossef LomnickyMichael Friedman OriginalPaper Pages: 1093 - 1097
Influence of Particle Size, Air Flow, and Inhaler Device on the Dispersion of Mannitol Powders as Aerosols Nora Y. K. ChewHak-Kim Chan OriginalPaper Pages: 1098 - 1103
Solute Absorption from the Airways of the Isolated Rat Lung. V. Charge Effects on the Absorption of Copolymers of N(2-hydroxyethyl)-DL-Aspartamide with DL-Aspartic Acid or Dimethylaminopropyl-DL-Aspartamide John Z. SunPeter R. ByronFrantisek Rypacek OriginalPaper Pages: 1104 - 1108
Confocal Raman-Spectroscopy: Analytical Approach to Solid Dispersions and Mapping of Drugs Jörg BreitenbachWolfgang SchrofJörg Neumann OriginalPaper Pages: 1109 - 1113
Biodegradable Nanoparticles Containing Doxorubicin-PLGA Conjugate for Sustained Release Hyuk Sang YooJong Eun OhTae Gwan Park OriginalPaper Pages: 1114 - 1118
The Effects of Absorbed Water on the Properties of Amorphous Mixtures Containing Sucrose Sheri L. ShamblinGeorge Zografi OriginalPaper Pages: 1119 - 1124
Complex Formation Between The Anionic Polymer (PAA) and a Cationic Drug (Procaine HC1): Characterization by Microcalorimetric Studies Thirumala GovenderTouraj EhtezaziStanley S. Davis OriginalPaper Pages: 1125 - 1131
Effects of Arbekacin and Vancomycin on Release of Lactate Dehydrogenase and Fragmentation of DNA in LLC-PK1 Kidney Epithelial Cells Tsutomu NakamuraToshiyuki KokuryoKen-Ichi Inui BriefCommunication Pages: 1132 - 1135
Development of an Unconventional In Vitro Drug Release Test Method for a Bile Acid Sequestrant, DMP 504, Tablet Lei-Shu WuTimothy J. McCormickMunir A. Hussain BriefCommunication Pages: 1136 - 1139
The Production of Uniformly Sized Polymer Microspheres Brian Amsden BriefCommunication Pages: 1140 - 1143
Truncated Area Under the Curve as a Measure of Relative Extent of Bioavailability: Evaluation Using Experimental Data and Monte Carlo Simulations Andre J. JacksonLarry A. Ouderkirk Letter to the Editor Pages: 1144 - 1146