Interview with a Distinguished Pharmaceutical Scientist: Bernard Testa Bernard Testa Legacy Pages: 593 - 596
Soluble Self-Assembled Block Copolymers for Drug Delivery Glen S. KwonTeruo Okano Commentary Pages: 597 - 600
Monolayers of Human Alveolar Epithelial Cells in Primary Culture for Pulmonary Absorption and Transport Studies Katharina J. ElbertUlrich F. SchäferClaus-Michael Lehr OriginalPaper Pages: 601 - 608
Competitive Inhibition of Glycylsarcosine Transport by Enalapril in Rabbit Renal Brush Border Membrane Vesicles: Interaction of ACE Inhibitors with High-Affinity H+/Peptide Symporter Chun-Jung LinWiyada AkarawutDavid E. Smith OriginalPaper Pages: 609 - 615
The pH-Partition Profile of the Anti-Ischemic Drug Trimetazidine May Explain Its Reduction of Intracellular Acidosis Frédéric ReymondGuillaume SteyaertBernard Testa OriginalPaper Pages: 616 - 624
Interplay Between CYP3A-Mediated Metabolism and Polarized Efflux of Terfenadine and Its Metabolites in Intestinal Epithelial Caco-2 (TC7) Cell Monolayers Shamsi D. RaeissiIsmael J. HidalgoPer Artursson OriginalPaper Pages: 625 - 632
The Nitric Oxide Donor SIN-1 Is Free of Tolerance and Maintains Its Cyclic GMP Stimulatory Potency in Nitrate-Tolerant LLC-PK1 Cells Burkhard HinzHenning Schröder OriginalPaper Pages: 633 - 636
Brain Penetration and In Vivo Recovery of NMDA Receptor Antagonists Amantadine and Memantine: A Quantitative Microdialysis Study Mayke B. HesselinkBert G. De BoerWojciech Danysz OriginalPaper Pages: 637 - 642
Immobilized Artificial Membrane (lAM)-HPLC for Partition Studies of Neutral and Ionized Acids and Bases in Comparison with the Liposomal Partition System Cornelia OttigerHeidi Wunderli-Allenspach OriginalPaper Pages: 643 - 650
NMR Studies of Retinoid-Protein Interactions: The Conformation of [13C]-β-Ionones Bound to β-Lactoglobulin B Robert W. Curley Jr.Appavu K. SundaramJohn L. Markley OriginalPaper Pages: 651 - 659
Development of a Mathematical Model for the Water Distribution in Freeze-Dried Solids Hak-Kim ChanKwok-Leung Au-YeungIgor Gonda OriginalPaper Pages: 660 - 665
Magnetic Resonance Imaging (MRI) as a Method to Investigate Movement of Water During the Extrusion of Pastes Gil TomerJohn Michael NewtonPaul Kinchesh OriginalPaper Pages: 666 - 671
Determination of the Viscosity of an Amorphous Drug Using Thermomechanical Analysis (TMA) Bruno C. HancockYves DupuisRoch Thibert OriginalPaper Pages: 672 - 675
Preparation of Biodegradable Microparticles Using Solution-Enhanced Dispersion by Supercritical Fluids (SEDS) Raouf GhaderiPer ArturssonJohan Carlfors OriginalPaper Pages: 676 - 681
A Novel System Based on a Poloxamer/ PLGA Blend as a Tetanus Toxoid Delivery Vehicle María TobíoJessica NolleyMaría José Alonso OriginalPaper Pages: 682 - 688
Interaction of Naproxen with Alpha-Cyclodextrin and Its Noncyclic Analog Maltohexaose Giampiero BettinettiMilena SorrentiFabrizio Melani OriginalPaper Pages: 689 - 694
Characterization of Recombinant Cytokine Fragments Using Isotachophoresis-Capillary Zone Electrophoresis, Reversed-Phase High Performance Liquid Chromatography, and Mass Spectrometry J. GyslerB. HelkJ. van der Greef OriginalPaper Pages: 695 - 701
A Central Composite Design to Investigate the Thermal Stabilization of Lysozyme Sébastien BranchuRobert T. ForbesHåkan Nyqvist OriginalPaper Pages: 702 - 708
The Effect of Collinearity on Parameter Estimates in Nonlinear Mixed Effect Models Peter L. Bonate OriginalPaper Pages: 709 - 717
Meal Composition Effects on the Oral Bioavailability of Indinavir in HIV-Infected Patients Peggy L. CarverDavid FleisherCheng Li OriginalPaper Pages: 718 - 724
Production and Characterization of 22 Monoclonal Antibodies Directed Against S 20499, a New Potent 5-HT1A Chiral Agonist: Influence of the Hapten Structure on Specificity and Stereorecognition Pierre GotEric RaimbaudJean-Michel Scherrmann OriginalPaper Pages: 725 - 735
Microdialysis Evaluation of the Ocular Pharmacokinetics of Propranolol in the Conscious Rabbit Kay D. RittenhouseRobert L. Peiffer Jr.Gary M. Pollack OriginalPaper Pages: 736 - 742
Noninvasive Assessment of Tumor Hypoxia with 99mTc Labeled Metronidazole David J. YangSeyfettin IlganDonald A. Podoloff OriginalPaper Pages: 743 - 750
Body Distribution of Camptothecin Solid Lipid Nanoparticles After Oral Administration Shicheng YangJiabi ZhuChangzheng Yang OriginalPaper Pages: 751 - 757
Electrorepulsion Versus Electroosmosis: Effect of pH on the lontophoretic Flux of 5-Fluorouracil Virginia MerinoAlicia LópezRichard H. Guy OriginalPaper Pages: 758 - 761
Preparation and Characterization of Carmustine Loaded Polyanhydride Wafers for Treating Brain Tumors Abraham J. DombZvi H. IsraelAlfonso Bentolila BriefCommunication Pages: 762 - 765
The Human Keratinocyte Cell Line HaCaT: An In Vitro Cell Culture Model for Keratinocyte Testosterone Metabolism Ralf AltenburgerThomas Kissel BriefCommunication Pages: 766 - 771
Analyzing Rich Data Using Different Methods Provided by NONMEM: Pharmacokinetics of Telmisartan Following Intravenous Infusion to Healthy Volunteers Gudrun Ch. WallensteinJoachim StangierThomas M. Ludden BriefCommunication Pages: 772 - 776