Genomics and Drugs: Finding the Optimal Drug for the Right Patient Wolfgang Sadée Commentary Pages: 959 - 963
MDCK Cell Cultures as an Epithelial In Vitro Model: Cytoskeleton and Tight Junctions as Indicators for the Definition of Age-Related Stages by Confocal Microscopy Barbara Rothen-RutishauserStefanie D. KrämerHeidi Wunderli-Allenspach OriginalPaper Pages: 964 - 971
Predicting Drug Absorption from Molecular Surface Properties Based on Molecular Dynamics Simulations Lene Hjorth KrarupInge Thøger ChristensenSven Frokjaer OriginalPaper Pages: 972 - 978
Dipeptide Uptake and Transport Characteristics in Rabbit Tracheal Epithelial Cell Layers Cultured at an Air Interface Fumiyoshi YamashitaKwang-Jin KimVincent H. L. Lee OriginalPaper Pages: 979 - 983
lontophoretic Permselectivity of Mammalian Skin: Characterization of Hairless Mouse and Porcine Membrane Models Asteria Luzardo-AlvarezMónica Rodríguez-FernándezM. Begoña Delgado-Charro OriginalPaper Pages: 984 - 987
In Vitro Cutaneous Disposition of a Topical Diclofenac Lotion in Human Skin: Effect of a Multi-Dose Regimen Philip G. HewittNicholas PobleteJ. Zev Shainhouse OriginalPaper Pages: 988 - 992
Inhibition of P-Glycoprotein: Rapid Assessment of Its Implication in Blood-Brain Barrier Integrity and Drug Transport to the Brain by an In Vitro Model of the Blood-Brain Barrier Laurence FenartValeric Buée-ScherrerMarie-Pierre Dehouck OriginalPaper Pages: 993 - 1000
Radioligand-Binding Assay Employing P-Glycoprotein-Overexpressing Cells: Testing Drug Affinities to the Secretory Intestinal Multidrug Transporter Stephan DöppenschmittHildegard Spahn-LangguthPeter Langguth OriginalPaper Pages: 1001 - 1006
Effect of Coadministered Uridine on Intestinal First-Pass Metabolism of 5′-Deoxy-5-Fluorouridine in Conscious Rats—An Evaluation by Method of Portal-Systemic Concentration Difference Yoneichi SawaiKiyoshi YamaokaTerumichi Nakagawa OriginalPaper Pages: 1007 - 1011
Evaluation of a Targeted Prodrug Strategy to Enhance Oral Absorption of Poorly Water-Soluble Compounds O. Helen ChanHeidi L. SchmidBarbra H. Stewart OriginalPaper Pages: 1012 - 1018
Low Swelling, Crosslinked Guar and Its Potential Use as Colon-Specific Drug Carrier Irit Gliko-KabirBoris YagenAbraham Rubinstein OriginalPaper Pages: 1019 - 1025
The Effect of Cross-Linking on the In Vivo Disintegration of Hard Gelatin Capsules J. BrownN. MaditD. Cadé OriginalPaper Pages: 1026 - 1030
Lectin-Mediated Drug Targeting: Preparation, Binding Characteristics, and Antiproliferative Activity of Wheat Germ Agglutinin Conjugated Doxorubicin on Caco-2 Cells Michael WirthAndrea FuchsFranz Gabor OriginalPaper Pages: 1031 - 1037
Liposphere Local Anesthetic Timed-Release for Perineural Site Application David B. MastersAbraham J. Domb OriginalPaper Pages: 1038 - 1045
Long-Circulating Nanopartides Bearing Heparin or Dextran Covalently Bound to Poly(Methyl Methacrylate) Catherine PassiraniGillian BarrattDenis Labarre OriginalPaper Pages: 1046 - 1050
Combined Poly(isobutylcyanoacrylate) and Cyclodextrins Nanoparticles for Enhancing the Encapsulation of Lipophilic Drugs Airton Monza da SilveiraGilles PonchelDominique Duchêne OriginalPaper Pages: 1051 - 1055
Preparation and Characterization of Nanocapsules from Preformed Polymers by a New Process Based on Emulsification-Diffusion Technique David Quintanar-GuerreroEric AllémannHatem Fessi OriginalPaper Pages: 1056 - 1062
Effects of Nitro-L-Arginine on Blood Pressure and Cardiac Index in Anesthetized Rats: A Pharmacokinetic-Pharmacodynamic Analysis Mohammad A. Tabrizi-FardHo-Leung Fung OriginalPaper Pages: 1063 - 1068
Development of a New Quantitative Approach for the Isobolographic Assessment of the Convulsant Interaction Between Pefloxacin and Theophylline in Rats Laurence M. LevasseurAnnie DelonWilliam Couet OriginalPaper Pages: 1069 - 1076
Evaluation of a Cmin and a Normalized Cmin Method for the Confirmation of Steady-State in Bioequivalence Studies André J. Jackson OriginalPaper Pages: 1077 - 1084
Lack of In Vivo/In Vitro Correlations for 50 mg and 250 mg Primidone Tablets Marvin C. MeyerArthur B. StraughnLarry J. Lesko OriginalPaper Pages: 1085 - 1089
Stability of Nonaqueous Suspension Formulations of Plasma Derived Factor IX and Recombinant Human Alpha Interferon at Elevated Temperatures Victoria M. KneppAnna MuchnikLarisa Kalashnikova OriginalPaper Pages: 1090 - 1095
Chemical Pathways of Peptide Degradation: IX. Metal-Catalyzed Oxidation of Histidine in Model Peptides Mehrnaz KhossraviRonald T. Borchardt OriginalPaper Pages: 1096 - 1102
Improving Stability and Release Kinetics of Microencapsulated Tetanus Toxoid by Co-Encapsulation of Additives Pål JohansenYing MenBruno Gander OriginalPaper Pages: 1103 - 1110
Enhanced Immunogenicity of Microencapsulated Tetanus Toxoid with Stabilizing Agents Régine AudranYing MenGiampietro Corradin OriginalPaper Pages: 1111 - 1116
Characterisation of the Glass Transition of an Amorphous Drug Using Modulated DSC Paul G. RoyallDuncan Q. M. CraigChristopher Doherty OriginalPaper Pages: 1117 - 1121
Compression Behavior of Orthorhombic Paracetamol Etienne JoirisPiera Di MartinoJean-Claude Guyot OriginalPaper Pages: 1122 - 1130
Viscoelastic Properties of Bioadhesive, Chlorhexidine-Containing Semi-Solids for Topical Application to the Oropharynx David S. JonesA. David WoolfsonAndrew F. Brown OriginalPaper Pages: 1131 - 1136
Effect of Hydrogen Peroxide on the Viscosity of a Hydroxyethylcellulose-Based Gel Terry DahlGong-Xin HeGlenn Samuels BriefCommunication Pages: 1137 - 1140
Quantification and Imaging of Mannitol Transport Through Caco-2 Cell Monolayers Using a Positron-Emitting Tracer Lucia LazorovaJohan GråsjöBengt Långström BriefCommunication Pages: 1141 - 1144
Nucleoside Transport in Isolated Human and Rhesus Choroid Plexus Tissue Slices Carla B. WashingtonKathleen M. GiacominiClaire M. Brett BriefCommunication Pages: 1145 - 1147