News From the National Institute of General Medical Sciences (NIGMS) Rochelle M. Long News Pages: 165 - 166
Bioequivalence of Topical Dermatological Dosage Forms-Methods of Evaluation of Bioequivalence Vinod P. ShahGordon L. FlynnRoger L. Williams Legacy Pages: 167 - 171
DNA Methylation as a Target for Drug Design Christina M. BenderJean-Marc ZinggPeter A. Jones ReviewPaper Pages: 175 - 187
Hydrophobic Ion Pairing: Altering the Solubility Properties of Biomolecules Jeffrey D. MeyerMark C. Manning ReviewPaper Pages: 188 - 193
Characterization of Frozen Aqueous Solutions by Low Temperature X-ray Powder Diffractometry Raghu K. CavaturRaj Suryanarayanan OriginalPaper Pages: 194 - 199
Interleukin-1 Receptor (IL-1R) Liquid Formulation Development Using Differential Scanning Calorimetry Richard L. Remmele Jr.Nancy S. NightlingerWayne R. Gombotz OriginalPaper Pages: 200 - 208
pH-Metric logP 10. Determination of Liposomal Membrane-Water Partition Coefficients of lonizable Drugs A. AvdeefK. J. BoxK. Y. Tam OriginalPaper Pages: 209 - 215
The Role of the Drug/Excipient Particle Size Ratio in the Percolation Model for Tablets Mónica MillánIsidore CaraballoAntonio María Rabasco OriginalPaper Pages: 216 - 220
Reduced Systemic Availability of an Antiarrhythmic Drug, Bidisomide, with Meal Co-administration: Relationship with Region-Dependent Intestinal Absorption Li-Heng PaoSimon Yuji ZhouDavid Fleisher OriginalPaper Pages: 221 - 227
Risedronate Gastrointestinal Absorption Is Independent of Site and Rate of Administration David Y. MitchellRachelle A. EusebioPirow J. Bekker OriginalPaper Pages: 228 - 232
Drug Marker Absorption in Relation to Pellet Size, Gastric Motility and Viscous Meals in Humans Julie K. RhieYayoi HayashiGordon L. Amidon OriginalPaper Pages: 233 - 238
Comparison of the Disposition of Ester Prodrugs of the Antiviral Agent 9-(2-phosphonylmethoxyethyl)adenine [PMEA] in Caco-2 Monolayers P. AnnaertG. GosselinP. Augustijns OriginalPaper Pages: 239 - 245
Permeation of Unfolded Basic Fibroblast Growth Factor (bFGF) Across Rabbit Buccal Mucosa—Does Unfolding of bFGF Enhance Transport? Thomas P. JohnstonAtiq RahmanAshim K. Mitra OriginalPaper Pages: 246 - 253
Effects of Non-Covalent Self-Association on the Subcutaneous Absorption of a Therapeutic Peptide Dean K. ClodfelterAllen H. PekarMark L. Brader OriginalPaper Pages: 254 - 262
Synthesis and In Vitro Evaluation of Chitosan-EDTA-Protease-Inhibitor Conjugates Which Might Be Useful in Oral Delivery of Peptides and Proteins Andreas Bernkop-SchnürchAndreas Scerbe-Saiko OriginalPaper Pages: 263 - 269
Stealth PLA-PEG Nanoparticles as Protein Carriers for Nasal Administration M. TobíoR. GrefM. J. Alonso OriginalPaper Pages: 270 - 275
Why Rate of Absorption Inferences in Single Dose Bioequivalence Studies are Often Inappropriate Rodney P. BassonAtalanta GhoshDaniel C. Howey OriginalPaper Pages: 276 - 279
Analysis of Chromameter Results Obtained from Corticosteroid-Induced Skin Blanching. I: Manipulation of Data Eric W. SmithJohn M. HaighRoderick B. Walker OriginalPaper Pages: 280 - 285
Dihydroorotate Dehydrogenase Inhibitors: Quantitative Structure-activity Relationship Analysis Shijun RenSharon K. WuEric J. Lien OriginalPaper Pages: 286 - 295
Biochemical Characterization of a Glucocorticoid-Induced Membrane Protein (RM3/1) in Human Monocytes and Its Application as Model System for Ranking Glucocorticoid Potency Petra HöggerUta ErpensteinClemens Sorg OriginalPaper Pages: 296 - 302
Pharmacological Activity and Membrane Interactions of Antiarrhythmics: 4D-QSAR/QSPR Analysis Christian D. P. KleinA. J. Hopfinger OriginalPaper Pages: 303 - 311
Influence of Surface Properties at Biodegradable Microsphere Surfaces: Effects on Plasma Protein Adsorption and Phagocytosis F. X. LacasseM. C. FilionP. Hildgen OriginalPaper Pages: 312 - 317
Modification of the Copolymers Poloxamer 407 and Poloxamine 908 can Affect the Physical and Biological Properties of Surface Modified Nanospheres Jonathan C. NealS. StolnikLisbeth Illum OriginalPaper Pages: 318 - 324
Efficacy and Pharmacokinetics of Site-Specific Cefazolin Delivery Using Biodegradable Implants in the Prevention of Post-operative Wound Infections Saleh AllababidiJaymin C. Shah OriginalPaper Pages: 325 - 333
DQAsomes: A Novel Potential Drug and Gene Delivery System Made from Dequalinium™ Volkmar WeissigJürgen LaschJeffrey Hughes OriginalPaper Pages: 334 - 337
Development and Utility of Anti-PepTl Anti-Peptide Polyclonal Antibodies Sujit K. BasuJie ShenHermann v. Grafenstein BriefCommunication Pages: 338 - 342
Reaction of Acyl Glucuronides with Insulin In Vitro: Identification of an Imine Mechanism by Electrospray lonization Mass Spectrometry J. H. LiuC. D. MarquezP. C. Smith BriefCommunication Pages: 343 - 346
Use of the Stable Isotopes Technique to Evaluate the Bioavailability of a Pharmaceutical Form of Magnesium in Man Henri BenechAlain PruvostJean-Marc Grognet BriefCommunication Pages: 347 - 351
A Cross-Section Device To Improve Visualization of Fluorescent Probe Penetration into the Skin by Confocal Laser Scanning Microscopy Marly E. M. J. MeuwissenJan JanssenJoke A. Bouwstra BriefCommunication Pages: 352 - 356
A Large-Scale Process to Produce Microencapsulated Proteins Paul HerbertKeith MurphyScott D. Putney BriefCommunication Pages: 357 - 361