Applications of the Ion-Pair Concept to Hydrophilic Substances with Special Emphasis on Peptides David Quintanar-GuerreroEric AllémannErie Doelker ReviewPaper Pages: 119 - 127
Drug Equilibration Across the Blood—Brain Barrier-Pharmacokinetic Considerations Based on the Microdialysis Method Margareta Hammarlund-UdenaesLennart K. PaalzowElizabeth C. M. de Lange OriginalPaper Pages: 128 - 134
The Pharmacists' Implementation of Pharmaceutical Care (PIPC) Model Folakemi T. OdedinaCharles D. HeplerDavid Miller OriginalPaper Pages: 135 - 144
The Association of Prescription Status, Patient Age, Patient Gender, and Patient Question Asking Behavior with the Content of Pharmacist−Patient Communication Jon C. SchommerJoseph B. Wiederholt OriginalPaper Pages: 145 - 151
The Use of Human Hepatocytes to Select Compounds Based on Their Expected Hepatic Extraction Ratios in Humans Th. LavéS. DupinPh. Coassolo OriginalPaper Pages: 152 - 155
Using Computer Simulated Results of a Bulk Drug Substance Assay to Determine Acceptance Criteria for Method Validation Richard D. Bunnell OriginalPaper Pages: 156 - 163
Effect of Size and Charge on the Passive Diffusion of Peptides Across Caco-2 Cell Monolayers via the Paracellular Pathway Giovanni M. PaulettiFranklin W. OkumuRonald T. Borchardt OriginalPaper Pages: 164 - 168
Effect of Restricted Conformational Flexibility on the Permeation of Model Hexapeptides Across Caco-2 Cell Monolayers Franklin W. OkumuGiovanni M. PaulettiRonald T. Borchardt OriginalPaper Pages: 169 - 175
Use of the Intestinal Bile Acid Transporter for the Uptake of Cholic Acid Conjugates with HIV-1 Protease Inhibitory Activity Matts KågedahlPeter W. SwaanSvein Øie OriginalPaper Pages: 176 - 180
Development and in Vitro Evaluation of Systems to Protect Peptide Drugs from Aminopeptidase N Andreas Bernkop-SchnürchMichaela K. Marschütz OriginalPaper Pages: 181 - 185
Activation of Signal Transduction Kinases by Tamoxifen Jauh-Lin DuhRong YuA.-N. Tony Kong OriginalPaper Pages: 186 - 189
Self-Assembling DNA-Lipid Particles for Gene Transfer Yuan-Peng ZhangDorothy L. ReimerMarcel B. Bally OriginalPaper Pages: 190 - 196
Binding of Prednisolone and Its Ester Prodrugs in the Skin Tomohiro HikimaKakuji Tojo OriginalPaper Pages: 197 - 202
Characterization of Pulmonary Alveolar Esterases of the Primate Cercopithecus pygerythrus Henry M. J. LengJames A. Syce OriginalPaper Pages: 203 - 207
The Equivalent Bronchodilator Effects of Salbutamol Formulated in Chlorofluorocarbon and Hydrofluoroalkane-134a Metered Dose Inhalers on the Histamine-Induced Pulmonary Response in Dogs Mari Nogami-ItohIkuhisa YakuoKunihiko Takeyama OriginalPaper Pages: 208 - 212
Pharmacokinetics and Antiepileptic Activity of Valproyl Hydroxamic Acid Derivatives Micha LeviBoris YagenMeir Bialer OriginalPaper Pages: 213 - 217
Formulation of a Charcoal Suspension for Intratumor Injection. Part 1: Study of the Nature, Granulometry, and Concentration L. Bonhomme-FaivreM. C. MathieuM. Seiller OriginalPaper Pages: 218 - 223
The Role of Liver and Kidney on the Pharmacokinetics of a Recombinant Amino Terminal Fragment of Bactericidal/Permeability-Increasing Protein in Rats Robert J. BauerKenneth DerAda H. C. Kung OriginalPaper Pages: 224 - 229
A Model with Separate Hepato-Portal Compartment ("First-Pass" Model): Fitting to Plasma Concentration-Time Profiles in Humans Vladimir PiotrovskijAchiel Van Peer OriginalPaper Pages: 230 - 237
Gly-L-Phe Transport and Metabolism Across Primary Cultured Rabbit Tracheal Epithelial Cell Monolayers Fumiyoshi YamashitaKwang-Jin KimVincent H. L. Lee Note Pages: 238 - 240
Pharmacodynamic Evaluation of Mitomycin C Analog BMS-181174 for Potential use in Intravesical Bladder Cancer Therapy Wan-Ching YenJessie L.-S. Au Note Pages: 241 - 245
Effects of Peptide Structure on Transport Properties of Seven Thyrotropin Releasing Hormone (TRH) Analogues in a Human Intestinal Cell Line (Caco-2) Ute WernerThomas KisselWerner Stüber Note Pages: 246 - 250
Bioavailability of Phenytoin and Anticonvulsant Activity after Oral Administration of Phenytoin-bis-hydroxyisobutyrate to Rats Gerhard K. E. ScribaDidier M. Lambert Note Pages: 251 - 253
In Memoriam: Dr. Harry Boddé, Associate Professor, Division of Pharmaceutical Technology, Leiden/Amsterdam Center for Drug Research (LACDR), Leiden University, The Netherlands D.D. Breimer Legacy Pages: 258 - 259