Molecular Mobility of Amorphous Pharmaceutical Solids Below Their Glass Transition Temperatures Bruno C. HancockSheri L. ShamblinGeorge Zografi OriginalPaper Pages: 799 - 806
Human Insulin Receptor Monoclonal Antibody Undergoes High Affinity Binding to Human Brain Capillaries in Vitro and Rapid Transcytosis Through the Blood–Brain Barrier in Vivo in the Primate William M. PardridgeYoung-Sook KangJing Yang OriginalPaper Pages: 807 - 816
Radiolabeling of Methylphosphonate and Phosphorothioate Oligonucleotides and Evaluation of Their Transport in Everted Rat Jejunum Sacs Jeffrey A. HughesAnna V. AvrutskayaR. L. Juliano OriginalPaper Pages: 817 - 824
The Fate of Plasmid DNA After Intravenous Injection in Mice: Involvement of Scavenger Receptors in Its Hepatic Uptake Kenji KawabataYoshinobu TakakuraMitsuru Hashida OriginalPaper Pages: 825 - 830
Development of an Efficient Single-Step Freeze-Drying Cycle for Protein Formulations Byeong S. ChangNorman L. Fischer OriginalPaper Pages: 831 - 837
Increased Stabilizing Effects of Amphiphilic Excipients on Freeze-Drying of Lactate Dehydrogenase (LDH) by Dispersion into Sugar Matrices Ken-ichi IzutsuSumie YoshiokaShigeo Kojima OriginalPaper Pages: 838 - 843
Comprehensive Pharmacokinetics of Urinary Human Follicle Stimulating Hormone in Healthy Female Volunteers J.-Y. le CotonnecH. C. PorchetM. Rowland OriginalPaper Pages: 844 - 850
Gamma Irradiation Effects on Molecular Weight and in Vitro Degradation of Poly(D,L-Lactide-CO-Glycolide) Microparticles Angela G. HausbergerRichard A. KenleyPatrick P. DeLuca OriginalPaper Pages: 851 - 856
Controlled Release of a Contraceptive Steroid from Biodegradable and Injectable Gel Formulations: In Vitro Evaluation Zhi-Hui GaoAtul J. ShuklaWilliam R. Crowley OriginalPaper Pages: 857 - 863
Controlled Release of Contraceptive Steroids from Biodegradable and Injectable Gel Formulations: In Vivo Evaluation Zhi-hui GaoWilliam R. CrowleyJames F. Reger OriginalPaper Pages: 864 - 868
Soft Drugs 18. Oral and Rectal Delivery of Loteprednol Etabonate, a Novel Soft Corticosteroid, in Rats—for Safer Treatment of Gastrointestinal Inflammation Nicholas BodorTeruo MurakamiWhei-Mei Wu OriginalPaper Pages: 869 - 874
Soft Drugs 19. Pharmacokinetics, Metabolism and Excretion of a Novel Soft Corticosteroid, Loteprednol Etabonate, in Rats Nicholas BodorWhei-Mei WuSteven Engel OriginalPaper Pages: 875 - 879
Evaluation of Intestinal Absorption into the Portal System in Enterohepatic Circulation by Measuring the Difference in Portal–Venous Blood Concentrations of Diclofenac Kenji TabataKiyoshi YamaokaTerumichi Nakagawa OriginalPaper Pages: 880 - 883
Regiospecific Intestinal Absorption of the HIV Protease Inhibitor L-735,524 in Beagle Dogs Gloria Y. KweiLinda B. NovakJuinn H. Lin OriginalPaper Pages: 884 - 888
Method to Estimate the Rate and Extent of Intestinal Absorption in Conscious Rats Using an Absorption Probe and Portal Blood Sampling Daniel J. HoffmanTerese SeifertHugh N. Nellans OriginalPaper Pages: 889 - 894
Interspecies Scaling of Tebufelone Pharmacokinetic Data and Application to Preclinical Toxicology Charles A. CruzeGary R. KelmMichael P. Meredith OriginalPaper Pages: 895 - 901
Effect of Corticosteroid Binding Globulin on the Pharmacokinetics of Prednisolone in Rats Hui C. KoRichard R. AlmonWilliam J. Jusko OriginalPaper Pages: 902 - 904
Pharmacokinetic Analysis and Antiepileptic Activity of N-Valproyl Derivatives of GABA and Glycine Salim HadadMeir Bialer OriginalPaper Pages: 905 - 910
Comparative Brain Exposure to (-)-Carbovir After (-)-Carbovir or (-)-6-Aminocarbovir Intravenous Infusion in Rats Yan-Dong WenRory P. RemmelCheryl L. Zimmerman OriginalPaper Pages: 911 - 915
Effect of Liposomal and Free Bisphosphonates on the IL-1β, IL-6 and TNFα Secretion from RAW 264 Cells in Vitro Niina PennanenSeppo LapinjokiJukka Mönkkönen OriginalPaper Pages: 916 - 922
The Effect of Moisture on the Mechanical and Powder Flow Properties of Microcrystalline Cellulose Gregory E. AmidonMichael E. Houghton OriginalPaper Pages: 923 - 929
5-Bromomethyl Fluorescein (5-BMF) for Derivatization of Carboxyl Containing Analytes for Use with Laser-Induced Fluorescence Detection Partha S. MukherjeeKapila H. DeSilvaH. Thomas Karnes OriginalPaper Pages: 930 - 936
Without Extrapolation, Cmax/AUC is an Effective Metric in Investigations of Bioequivalence Laszlo TothfalusiLaszlo Endrenyi Note Pages: 937 - 942