Antigene, Ribozyme and Aptamer Nucleic Acid Drugs: Progress and Prospects Robert A. StullFrancis C. Szoka, Jr ReviewPaper Pages: 465 - 483
Thermal Analysis of the Tertiary Butyl Alcohol-Water System and Its Implications on Freeze-Drying Kasra KasraianPatrick P. DeLuca OriginalPaper Pages: 484 - 490
The Effect of Tertiary Butyl Alcohol on the Resistance of the Dry Product Layer During Primary Drying Kasra KasraianPatrick P. DeLuca OriginalPaper Pages: 491 - 495
Physico-Mechanical Characterization of the Extrusion-Spheronization Process. Part II: Rheological Determinants for Successful Extrusion and Spheronization Rajen D. ShahMohan KabadiLarry L. Augsburger OriginalPaper Pages: 496 - 507
Monosialoganglioside GMl Shortens the Blood Circulation Time of Liposomes in Rats Dexi LiuFeng LiuYoung K. Song OriginalPaper Pages: 508 - 512
Insulin-Degrading Enzyme in a Human Colon Adenocarcinoma Cell Line (Caco-2) Jane P. F. BaiMatt J. P. HsuW. Thomas Shier OriginalPaper Pages: 513 - 517
Is the Beneficial Effect of Calcium Channel Blockers Against Cyclosporine A Toxicity Related to a Restoration of ATP Synthesis? Marie D. SalducciAnne M. Chauvet-MongesAimé D. Crevat OriginalPaper Pages: 518 - 522
Characterization of Drug Transport Through Tight-Junctional Pathway in Caco-2 Monolayer: Comparison with Isolated Rat Jejunum and Colon Yoshihiro TanakaYoko TakiShinji Yamashita OriginalPaper Pages: 523 - 528
Ocular Absorption and Irritation of Pilocarpine Prodrug Is Modified with Buffer, Polymer, and Cyclodextrin in the Eyedrop Pekka SuhonenTomi JärvinenArto Urtti OriginalPaper Pages: 529 - 533
Evaluation of Poly(isobutylcyanoacrylate) Nanoparticles for Mucoadhesive Ocular Drug Delivery. I. Effect of Formulation Variables on Physicochemical Characteristics of Nanoparticles Sudip K. DasIan G. TuckerNandita Ganguly OriginalPaper Pages: 534 - 540
Measurement of Rapid Release Kinetics for Drug Delivery Uwe PliquettMark R. PrausnitzJames C. Weaver OriginalPaper Pages: 549 - 555
Effect of Humidity-Dependent Changes in Crystal Structure on the Solid-State Fluorescence Properties of a New HMG-CoA Reductase Inhibitor Harry G. BrittainSunanda A. RanadiveAbu T. M. Serajuddin OriginalPaper Pages: 556 - 559
Effects of Inclusion Complexation on the Transepithelial Transport of a Lipophilic Substance in Vitro M. J. ChoF. J. ChenDennis L. Huczek OriginalPaper Pages: 560 - 564
Development of a Human Nasal Epithelial Cell Culture Model and Its Suitability for Transport and Metabolism Studies Under in Vitro Conditions Ute WernerThomas Kissel OriginalPaper Pages: 565 - 571
Use of ATR-FTIR Spectroscopy to Study the Diffusion of Ethanol Through Glycerogelatin Films A. Margarida L. TralhãoAdam C. WatkinsonN. Anthony Armstrong OriginalPaper Pages: 572 - 575
In Vitro Evaluation of Polymerized Liposomes as an Oral Drug Delivery System Jun'ichi OkadaSmadar CohenRobert Langer OriginalPaper Pages: 576 - 582
QSAR Analysis of Skin Permeability of Various Drugs in Man as Compared to in Vivo and in Vitro Studies in Rodents Eric J. LienHua Gaot OriginalPaper Pages: 583 - 587
The in Vitro Characterization and Biostability of 99mTc-Dextran and Its Accumulation Within the Inflamed Paws of Adjuvant-Induced Arthritic Rats Ian W. KellawayLisa SealePaul S. J. Spencer OriginalPaper Pages: 588 - 593
Relationship Between the Phasic Period of Interdigestive Migrating Contraction and the Systemic Bioavailability of Acetaminophen in Dogs Kazuyoshi SagaraHiroaki MizutaKeiichiro Haga OriginalPaper Pages: 594 - 598
Isothermal and Nonisothermal Decomposition of Famotidine in Aqueous Solution Gunjan H. JunnarkarSalomon Stavchansky OriginalPaper Pages: 599 - 604
Transport Mechanism of Ceftibuten, a Dianionic Cephem, in Rat Renal Brush-Border Membrane Imad NaasaniMitsuru SugawaraKatsumi Miyazaki OriginalPaper Pages: 605 - 608
Metabolism of Diltiazem in Hepatic and Extrahepatic Tissues of Rabbits: In Vitro Studies Walid HomsyMarc LefebvrePatrick du Souich OriginalPaper Pages: 609 - 614
A Cellular Automata Model of the Hydrophobia Effect Lemont B. KierChao-Kun ChengPierre-Alain Carrupt OriginalPaper Pages: 615 - 620
A Solution Conformation Analysis of Forocidins I and Isoforocidins I Using NMR and Molecular Modeling Kumar RamuSachin ShringarpureJohn S. Williamson Note Pages: 621 - 629
Amoebicidal in Vitro Activity Shown by Some Metronidazole Analogues: Biological Response-Reduction Potential Correlation Ma. Elena CamposMarco MerazHéctor Salgado-Zamora Note Pages: 630 - 633
Solution Properties of Two Fluoroquinolone Antibacterials Richard J. Prankerd Letter to the Editor Pages: 634 - 635