WHAT IS THE CURRENT NIGMS SCORING EXPERIMENT? HOW DOES IT WORK? WHAT IS IT ATTEMPTING TO ACCOMPLISH? Rochelle M. Long News Pages: 1560 - 1560
Lipid Microemulsions for Improving Drug Dissolution and Oral Absorption: Physical and Biopharmaceutical Aspects Panayiotis P. Constantinides ReviewPaper Pages: 1561 - 1572
Does Fluid Flow Across the Intestinal Mucosa Affect Quantitative Oral Drug Absorption? Is It Time for a Reevaluation? Hans Lennernäs ReviewPaper Pages: 1573 - 1582
Stabilization of the Hydrophilic Sphere of lobitridol, an lodinated Contrast Agent, as Revealed by Experimental and Computational Investigations Dominique MeyerMarie-Hélène FouchetBernard Testa OriginalPaper Pages: 1583 - 1591
Pharmacokinetics and Anticonvulsant Effect of a New Hypnotic, CL 284,846, in Rats Jacques GaudreaultFrance VarinGary M. Pollack OriginalPaper Pages: 1592 - 1597
Human MCAF Gene Transfer Enhances the Metastatic Capacity of a Mouse Cachectic Adenocarcinoma Cell Line in Vivo Emi NakashimaNaofumi MukaidaKouji Matsushima OriginalPaper Pages: 1598 - 1604
The Electrical Characteristics of Human Skin in Vivo Yogeshvar N. KaliaRichard H. Guy OriginalPaper Pages: 1605 - 1613
Apparent pKa of the Fatty Acids Within Ordered Mixtures of Model Human Stratum Corneum Lipids Renate LieckfeldtJosé VillalaínGeoffrey Lee OriginalPaper Pages: 1614 - 1617
Effect of PGML Excipient Mixture in a Transdermal System on the in Vitro Transport of Estradiol Across Skin Gretchen D. IrionMichael D. GarrisonWilliam Abraham OriginalPaper Pages: 1618 - 1622
Iontophoresis Enhances the Transport of Acyclovir Through Nude Mouse Skin by Electrorepulsion and Electroosmosis Nadia Maria VolpatoPatrizia SantiPaolo Colombo OriginalPaper Pages: 1623 - 1627
A Predictive Algorithm for Skin Permeability: The Effects of Molecular Size and Hydrogen Bond Activity Russell O. PottsRichard H. Guy OriginalPaper Pages: 1628 - 1633
Evaluation of Bioequivalence of Highly Variable Drugs Using Monte Carlo Simulations. I. Estimation of Rate of Absorption for Single and Multiple Dose Trials Using Cmax Ahmed A. El-TahtawyAndré J. JacksonThomas M. Ludden OriginalPaper Pages: 1634 - 1641
Effect of Omeprazole on Diazepam Disposition in the Rat: in Vitro and in Vivo Studies K. ZomorodiJ. B. Houston OriginalPaper Pages: 1642 - 1646
Effects of Gender, Pregnancy, and Anesthesia on the Pharmacokinetics of Zidovudine in Rats Christine S.-H. HuangF. Douglas BoudinotStuart Feldman OriginalPaper Pages: 1647 - 1651
The Problem of Racemization in the Stereospecific Assay and Pharmacokinetic Evaluation of Ketorolac in Human and Rats Majid VakilyBrian CorriganFakhreddin Jamali OriginalPaper Pages: 1652 - 1657
Inhibition of Pulmonary Surfactant Biophysical Activity by Cationic Polyamino Acids Paul M. BummerShewan AzizMark N. Gillespie OriginalPaper Pages: 1658 - 1663
The Application of Crystal Soaking Technique to Study the Effect of Zinc and Cresol on Insulinotropin Crystals Grown from a Saline Solution Yesook KimAnne M. Haren OriginalPaper Pages: 1664 - 1670
Estimation of Recombinant Bovine Somatotropin Solubility by Excluded-Volume Interaction with Polyethylene Glycols Cynthia L. StevensonMichael J. Hageman OriginalPaper Pages: 1671 - 1676
Loading Effect on Particle Size Measurements by Inertial Sampling of Albuterol Metered Dose Inhalers Moheb M. NasrJames F. Allgire OriginalPaper Pages: 1677 - 1681
Nebulization of Fluids of Different Physicochemical Properties with Air-Jet and Ultrasonic Nebulizers Orla N. M. McCallionKevin M. G. TaylorAnthony J. Taylor OriginalPaper Pages: 1682 - 1688
A Microcalorimetric Investigation of the Interaction of Surfactants with Crystalline and Partially Crystalline Salbutamol Sulphate in a Model Inhalation Aerosol System Peter M. BlackettGraham Buckton OriginalPaper Pages: 1689 - 1693
Structure of Disintegrating Pellets with Regard to Fractal Geometry Martin SchröderPeter Kleinebudde OriginalPaper Pages: 1694 - 1700
Thermophysical Properties of Some Pharmaceutical Excipients Compressed in Tablets Jarkko KetolainenL'udovit KubičárPetteri Paronen OriginalPaper Pages: 1701 - 1707
Photoinstability of Some Tyrphostin Drugs: Chemical Consequences of Crystallinity Narendra KumarVincent WindischHerman L. Ammon OriginalPaper Pages: 1708 - 1715
Absorption and Presystemic Metabolism of Nefazodone Administered at Different Regions in the Gastrointestinal Tract of Humans Punit H. MaratheDaniel E. SalazarRashmi H. Barbhaiya OriginalPaper Pages: 1716 - 1721
The Site of Absorption in the Small Intestine Determines Diltiazem Bioavailability in the Rabbit Walid HomsyGilles CailléPatrick du Souich OriginalPaper Pages: 1722 - 1726
Proton-Cotransport of Pravastatin Across Intestinal Brush-Border Membrane Ikumi TamaiHitomi TakanagaAkira Tsuji OriginalPaper Pages: 1727 - 1732
Sucrose Urinary Excretion in the Rat Measured Using a Simple Assay: A Model of Gastroduodenal Permeability Neal M. DaviesBrian W. CorriganFakhreddin Jamali OriginalPaper Pages: 1733 - 1736
Contribution of Parenchymal and Non-Parenchymal Liver Cells to the Clearance of Hepatocyte Growth Factor From the Circulation in Rats Ke-Xin LiuYukio KatoYuichi Sugiyama OriginalPaper Pages: 1737 - 1740
Evaluation of the Uptake of Pravastatin by Perfused Rat Liver and Primary Cultured Rat Hepatocytes Michi IshigamiTaro TokuiYuichi Sugiyama OriginalPaper Pages: 1741 - 1745
Kinetic Analysis of Hepatobiliary Transport for Conjugated Metabolites in the Perfused Liver of Mutant Rats (EHBR) with Hereditary Conjugated Hyperbilirubinemia Osamu TakenakaToru HorieYuichi Sugiyama OriginalPaper Pages: 1746 - 1755
Hepatoprotective Activity of Xanthones and Xanthonolignoids Against tert-Butylhydroperoxide-Induced Toxicity in Isolated Rat Hepatocytes—Comparison with Silybin Eduarda R. FernandasFélix D. CarvalhoOtto R. Gottlieb OriginalPaper Pages: 1756 - 1760
Gamma-Irradiation of Non-Frozen, Frozen, and Freeze-Dried Liposomes Nicolaas J. ZuidamStephen S. L. LeeDaan J. A. Crommelin OriginalPaper Pages: 1761 - 1768
Enhanced Therapeutic Effect of Cytidine-5′ -Diphosphate Choline when Associated with GM1 Containing Small Liposomes as Demonstrated in a Rat Ischemia Model Massimo FrestaErnst WehrliGiovanni Puglisi OriginalPaper Pages: 1769 - 1774
Antibody Dependent, Complement Mediated Liver Uptake of Liposomes Containing GM1 Dexi LiuYoung K. SongFeng Liu OriginalPaper Pages: 1775 - 1780
Drug Release From Hydrocolloid Embeddings with High or Low Susceptibility to Hydrodynamic Stress Wolfram D. LindnerBernhard C. Lippold OriginalPaper Pages: 1781 - 1785
The Release of 5-Fluorouracil from a Swellable Matrix of a Triblock Copolymer of ε-Caprolactone and Ethylene Oxide Luigi G. A. MartiniJohn H. CollettDavid Attwood OriginalPaper Pages: 1786 - 1790
Ocular Availability of Gentamicin in Small Animals After Topical Administration of a Conventional Eye Drop Solution and a Novel Long Acting Bioadhesive Ophthalmic Drug Insert Florian GurtlerVassilios KaltsatosRobert Gurny OriginalPaper Pages: 1791 - 1795
Biodegradable Delivery System for a Birth Control Vaccine: Immunogenicity Studies in Rats and Monkeys Manmohan SinghOm SinghG. P. Talwar OriginalPaper Pages: 1796 - 1800
Transport of Peptidomimetic Renin Inhibitors Across Monolayers of a Human Intestinal Cell Line (Caco-2): Evidence for Self-Enhancement of Paracellular Transport Route Elke WalterThomas KisselPeter Raddatz Note Pages: 1801 - 1805
Reconversion of Fosphenytoin in the Presence of Intestinal Alkaline Phosphatase Christopher N. TenHoorBarbra H. Stewart Note Pages: 1806 - 1809
A Novel Isolation Method of a Stable Crystalline Salt of a Cyclic RGD Peptide Zwitterion Michael B. MaurinMunir A. Hussain Note Pages: 1810 - 1812
Ionic Strength Dependence of Dissolution for Eudragit S-100 Coated Pellets Tugrul T. KararliCarol F. KirchhoffJames E. Truelove Note Pages: 1813 - 1816
