1. Strategies for Indirect Computer-Aided Drug Design

   • Gilda H. Loew
   • Hugo O. Villar
   • Ibon Alkorta

   ReviewPaper Pages: 475 - 486

2. Controlled Delivery Systems for Proteins Using Polyanhydride Microspheres

   • Yasuhiko Tabata
   • Sunitha Gutta
   • Robert Langer

   OriginalPaper Pages: 487 - 496

3. A New Method for Estimating Dermal Absorption from Chemical Exposure. 1. General Approach

   • Robert L. Cleek
   • Annette L. Bunge

   OriginalPaper Pages: 497 - 506

4. Immunotargeting of Liposomes Containing Lipophilic Antitumor Prodrugs

   • Atsuhide Mori
   • Stephen J. Kennel
   • Leaf Huang

   OriginalPaper Pages: 507 - 514

5. Synthesis and Testing of New Antileukemic Schiff Bases of N-Hydroxy-N′ - Aminoguanidine Against CCRF-CEM/0 Human Leukemia Cells in Vitro and Synergism Studies with Cytarabine (Ara-C)

   • Phanesh B. Koneru
   • Eric J. Lien
   • Vassilios I. Avramis

   OriginalPaper Pages: 515 - 520

6. Taxol and Related Taxanes. I. Taxanes of Taxus brevifolia Bark

   • Koppaka V. Rao

   OriginalPaper Pages: 521 - 524

7. Aqueous Ethylcellulose Dispersion of Ethylcellulose. I. Evaluation of Coating Process Variables

   • Nilesh H. Parikh
   • Stuart C. Porter
   • Bhagwan D. Rohera

   OriginalPaper Pages: 525 - 534

8. A Method for the Early Evaluation of the Effects of Storage and Additives on the Stability of Parenteral Fat Emulsions

   • Jianmin Li
   • Karin D. Caldwell
   • Bradley D. Anderson

   OriginalPaper Pages: 535 - 541

9. The Influence of Thermal Treatment on the Physical-Mechanical and Dissolution Properties of Tablets Containing Poly(DL-Lactic Acid)

   • Marcelo O. Omelczuk
   • James W. McGinity

   OriginalPaper Pages: 542 - 548

10. Uptake of Phosphatidylserine Liposomes by Rat Peyer's Patches Following Intraluminal Administration

    • Hitoshi Tomizawa
    • Yukihiko Aramaki
    • Seishi Tsuchiya

    OriginalPaper Pages: 549 - 552

11. In Vitro Nasal Transport Across Ovine Mucosa: Effects of Ammonium Glycyrrhizinate on Electrical Properties and Permeability of Growth Hormone Releasing Peptide, Mannitol, and Lucifer Yellow

    • Patricia M. Reardon
    • Caroline H. Gochoco
    • Philip L. Smith

    OriginalPaper Pages: 553 - 561

12. Development of Activity Assays for High-Volume Evaluation of Human Immunodeficiency Virus (HIV) Protease Inhibitors in Rat Serum: Results with Ditekiren

    • Karen F. Wilkinson
    • Bob D. Rush
    • Paul K. Tomich

    OriginalPaper Pages: 562 - 566

13. Pharmacokinetics of Recombinant Human Interferon-β_ser in Healthy Volunteers and Its Effect on Serum Neopterin

    • Janie Chiang
    • Carol A. Gloff
    • Gary J. Williams

    OriginalPaper Pages: 567 - 572

14. Decreased Cellular Toxicity of Neomycin in a Clonal Cell Line Isolated from LLC-PK₁

    • Ryohei Hori
    • Masahiro Okuda
    • Mikihisa Takano

    OriginalPaper Pages: 573 - 576

15. Physicochemical Stability of Phenobarbital Polymorphs at Various Levels of Humidity and Temperature

    • Makoto Otsuka
    • Mika Onoe
    • Yoshihisa Matsuda

    OriginalPaper Pages: 577 - 582

16. An in Vitro Study of Diamorphine Permeation Through Premature Human Neonatal Skin

    • David A. Barrett
    • Nicholas Rutter
    • Stanley S. Davis

    OriginalPaper Pages: 583 - 587

17. In Vivo/in Vitro Correlation of Experimental Sustained-Release Theophylline Formulations

    • Kah-Hay Yuen
    • Arvind A. Desmukh
    • John M. Newton

    OriginalPaper Pages: 588 - 592

18. Comparison of the Pharmacokinetics and Pharmacodynamics of the Aldose Reductase Inhibitors, AL03152 (RS), AL03802 (R), and AL03803 (S)

    • Young Han Park
    • Philip R. Mayer
    • John T. Slattery

    OriginalPaper Pages: 593 - 597

19. Pharmacokinetic Monitoring in Subcutaneous Tissue Using in Vivo Capillary Ultrafiltration Probes

    • Michael C. Linhares
    • Peter T. Kissinger

    OriginalPaper Pages: 598 - 602

20. Clinical Pharmacokinetics and Relative Bioavailability of Oral Procaterol

    • Michael A. Eldon
    • Michele M. Battle
    • Wayne A. Colburn

    OriginalPaper Pages: 603 - 605

21. Distinction Between the Depletion of Opsonins and the Saturation of Uptake in the Dose-Dependent Hepatic Uptake of Liposomes

    • Hideyoshi Harashima
    • Kazuya Sakata
    • Hiroshi Kiwada

    OriginalPaper Pages: 606 - 610

22. Formycin B Elimination from the Cerebrospinal Fluid of the Rat

    • Xiaochun Wu
    • Andrew C. Hui
    • Kathleen M. Giacomini

    OriginalPaper Pages: 611 - 615

23. The Determination of Diffusion Coefficients in Semisolids by Fourier Transform Infrared (FT-IR) Spectroscopy

    • Dale Eric Wurster
    • Varaporn Buraphacheep
    • Jatin M. Patel

    OriginalPaper Pages: 616 - 620

24. Optimization of Conditions for Preparing 2- to 5-Micron-Range Gelatin Microparticles by Using Chilled Dehydration Agents

    • Levent Öner
    • Michael J. Groves

    Note Pages: 621 - 626

25. Molecular Cloning of the Alcohol/Hydroxysteroid Form (mST _a1) of Sulfotransferase from Mouse Liver

    • Ah-Ng Tony Kong
    • Deling Tao
    • Linding Yang

    Note Pages: 627 - 630

26. Micellar Solubilization of Clofazimine Analogues in Aqueous Solutions of Ionic and Nonionic Surfactants

    • Khairi M. S. Fahelelbom
    • Richard F. Timoney
    • Owen I. Corrigan

    Note Pages: 631 - 634

27. BOOK REVIEWS

    BookReview Pages: 635 - 635

28. Letters to the Editor

    • Russell O. Potts
    • Richard H. Guy
    • Alien R. Hilgers

    Letter to the Editor Pages: 635 - 637

29. Association News and Announcements

    Announcement Pages: 638 - 638