Solid-State Nuclear Magnetic Resonance Spectroscopy: Theory and Pharmaceutical Applications David E. Bugay ReviewPaper Pages: 317 - 327
Solid-State Diode Laser-Induced Fluorescence Detection in High-Performance Liquid Chromatography Sadayappan V. RahavendranH. Thomas Karnes ReviewPaper Pages: 328 - 334
In Vivo Microdialysis Sampling in the Bile, Blood, and Liver of Rats to Study the Disposition of Phenol Dennis O. ScottCraig E. Lunte OriginalPaper Pages: 335 - 342
Antitumor Agents 126. Novel 4β-Substituted Anilino Derivatives of 3′,4′ -O, O-Didemethylpodophyllotoxin as Potent Inhibitors of Human DNA Topoisomerase II Zhe-Qing WangYa-Ching ShenKuo-Hsiung Lee OriginalPaper Pages: 343 - 350
Low-Substituted Hydroxypropylcellulose as a Sustained-Drug Release Matrix Base or Disintegrant Depending on Its Particle Size and Loading in Formulation Yoshiaki KawashimaHirofumi TakeuchiKeiko Kawahara OriginalPaper Pages: 351 - 355
Drug Release Mechanism from a Microcrystalline Cellulose Pellet System Robert E. O'ConnorJoseph B. Schwartz OriginalPaper Pages: 356 - 361
The Preparation and Characterization of Poly(lactide-co-glycolide) Microparticles. II. The Entrapment of a Model Protein Using a (Water-in-Oil)-in-Water Emulsion Solvent Evaporation Technique Hayley JefferyStanley S. DavisDerek T. O'Hagan OriginalPaper Pages: 362 - 368
Tissue Response to Bioerodible, Subcutaneous Drug Implants: A Possible Determinant of Drug Absorption Kinetics F. D. AndersonD. F. ArcherW. H. Wilborn OriginalPaper Pages: 369 - 380
Electrochemical Characterization of Human Skin by Impedance Spectroscopy: The Effect of Penetration Enhancers Kyösti KontturiLasse MurtomäkiArto Urtti OriginalPaper Pages: 381 - 385
Poly(ε-Caprolactone) Nanocapsules in Carteolol Ophthalmic Delivery Laurent Marchal-HeusslerDaniel SirbatPhilippe Maincent OriginalPaper Pages: 386 - 390
Polyanhydride Mierospheres that Display Near-Constant Release of Water-Soluble Model Drug Compounds Yasuhiko TabataRobert Langer OriginalPaper Pages: 391 - 399
Peptide Carrier-Mediated Transport in Intestinal Brush Border Membrane Vesicles of Rats and Rabbits: Cephradine Uptake and Inhibition Hiroaki YuasaGordon L. AmidonDavid Fleisher OriginalPaper Pages: 400 - 404
An Investigation into the Mechanical and Transport Properties of Aqueous Latex Films: A New Hypothesis for the Film-Forming Mechanism of Aqueous Dispersion System Jian-Hwa GuoRichard E. RobertsonGordon L. Amidon OriginalPaper Pages: 405 - 410
Viscoelasticity of Anionic Polymers and Their Mucociliary Transport on the Frog Palate Shun Y. LinGordon L. AmidonArthur H. Goldberg OriginalPaper Pages: 411 - 417
Disposition of Azole Antifungal Agents. I. Nonlinearities in Ketoconazole Clearance and Binding in Rat Liver Diane MatthewBeverley BrennanJ. Brian Houston OriginalPaper Pages: 418 - 422
Interaction of Nucleoside Analogues with the Sodium–Nucleoside Transport System in Brush Border Membrane Vesicles from Human Kidney Claire M. BrettCarla B. WashingtonKathleen M. Giacomini OriginalPaper Pages: 423 - 426
Pharmacokinetics of a Novel Antiarrhythmic Drug, Actisomide Chyung S. CookLeonard F. RozekAziz Karim OriginalPaper Pages: 427 - 433
Comparison of the Hepatic Uptake Clearances of Fifteen Drugs with a Wide Range of Membrane Permeabilities in Isolated Rat Hepatocytes and Perfused Rat Livers Seiji MiyauchiYasufumi SawadaYuichi Sugiyama OriginalPaper Pages: 434 - 440
Rapid Determination of Methadone in Plasma, Cerebrospinal Fluid, and Urine by Gas Chromatography and Its Application to Routine Drug Monitoring Norbert SchmidtReinhard SittlGerd Geisslinger OriginalPaper Pages: 441 - 444
Stabilization of Oxygen-Sensitive Formulations via a Secondary Oxygen Scavenger Carol L. MayersDennis R. Jenke OriginalPaper Pages: 445 - 448
Three Approaches to the Analysis of Trace Formaldehyde in Bulk and Dosage Form Pharmaceuticals Gerald J. ManiusLan-Fun Li WenDavid Palling OriginalPaper Pages: 449 - 453
Axial Ratio Measurements for Early Detection of Crystal Growth in Suspension-Type Metered Dose Inhalers Elaine M. PhillipsPeter R. ByronRichard N. Dalby Note Pages: 454 - 456
Loading of Bovine Serum Albumin into Hydrogels by an Electrophoretic Process and Its Potential Application to Protein Drugs Waleed S. W. ShalabyAnna A. AbdallahKinam Park Note Pages: 457 - 460
Molecular Cloning of Two cDNAs Encoding the Mouse Bilirubin/Phenol Family of UDP-Glucuronosyltransferases (mUGT Br/p) Ah-Ng Tony KongMeihui MaLinding Yang Note Pages: 461 - 465
Feasibility of Developing a Neural Network for Prediction of Human Pharmacokinetic Parameters from Animal Data Ajaz S. HussainRobert D. JohnsonWolfgang A. Ritschel Note Pages: 466 - 469
Formation of a Chromophoric Complex Between Alendronate and Copper(II) Ions Dražen OstovićChristine StelmachBecky Hulshizer Note Pages: 470 - 472