1. In Vitro and In Vivo Characterisation of PEG-Lipid-Based Micellar Complexes of Salmon Calcitonin for Pulmonary Delivery

   • Leonie Baginski
   • Oliviero L. Gobbo
   • Carsten Ehrhardt

   Research Paper 10 February 2012 Pages: 1425 - 1434

   

2. Sterically Stabilized Liposomes Incorporating the Novel Anticancer Agent Phospho-Ibuprofen (MDC-917): Preparation, Characterization, and In Vitro/In Vivo Evaluation

   • George Mattheolabakis
   • Ting Nie
   • Basil Rigas

   Research Paper 10 November 2011 Pages: 1435 - 1443

   

3. Use of Artificial Digestive Systems to Investigate the Biopharmaceutical Factors Influencing the Survival of Probiotic Yeast During Gastrointestinal Transit in Humans

   • Stéphanie Blanquet-Diot
   • Sylvain Denis
   • Monique Alric

   Research Paper 09 November 2011 Pages: 1444 - 1453

   

4. Tungsten-Induced Denaturation and Aggregation of Epoetin Alfa During Primary Packaging as a Cause of Immunogenicity

   • Andreas Seidl
   • Otmar Hainzl
   • Iain Macdougall

   Research Paper Open access 18 November 2011 Pages: 1454 - 1467

   

5. Polymeric Nanoparticles Affect the Intracellular Delivery, Antiretroviral Activity and Cytotoxicity of the Microbicide Drug Candidate Dapivirine

   • José das Neves
   • Johan Michiels
   • Bruno Sarmento

   Research Paper 10 November 2011 Pages: 1468 - 1484

   

6. Application of Dissolution/Permeation System for Evaluation of Formulation Effect on Oral Absorption of Poorly Water-Soluble Drugs in Drug Development

   • Makoto Kataoka
   • Kiyohiko Sugano
   • Shinji Yamashita

   Research Paper 02 December 2011 Pages: 1485 - 1494

   

7. Transferrin Adsorption onto PLGA Nanoparticles Governs Their Interaction with Biological Systems from Blood Circulation to Brain Cancer Cells

   • Jiang Chang
   • Archibald Paillard
   • Emmanuel Garcion

   Research Paper 14 December 2011 Pages: 1495 - 1505

   

8. Apigenin Attenuates Insulin-Like Growth Factor-I Signaling in an Autochthonous Mouse Prostate Cancer Model

   • Sanjeev Shukla
   • Gregory T. MacLennan
   • Sanjay Gupta

   Research Paper 03 December 2011 Pages: 1506 - 1517

   

9. Population Pharmacokinetic/Pharmacodynamic Model for the Sedative Effects of Flibanserin in Healthy Volunteers

   • Iñaki F. Trocóniz
   • Katja Boland
   • Alexander Staab

   Research Paper 05 January 2012 Pages: 1518 - 1529

   

10. Adaptive Optimal Design for Bridging Studies with an Application to Population Pharmacokinetic Studies

    • Lee Kien Foo
    • Stephen Duffull

    Research Paper 14 February 2012 Pages: 1530 - 1543

    

11. Accurate Prediction of Glucuronidation of Structurally Diverse Phenolics by Human UGT1A9 Using Combined Experimental and In Silico Approaches

    • Baojian Wu
    • Xiaoqiang Wang
    • Ming Hu

    Research Paper 03 February 2012 Pages: 1544 - 1561

    

12. Targeted Delivery of Proteins into the Central Nervous System Mediated by Rabies Virus Glycoprotein-Derived Peptide

    • Ailing Fu
    • Yilin Wang
    • Rumei Zhou

    Research Paper 10 January 2012 Pages: 1562 - 1569

    

13. A Bodyweight-Dependent Allometric Exponent for Scaling Clearance Across the Human Life-Span

    • Chenguang Wang
    • Mariska Y. M. Peeters
    • Catherijne A. J. Knibbe

    Research Paper Open access 28 January 2012 Pages: 1570 - 1581

    

14. PEG-Stabilized Micellar System with Positively Charged Polyester Core for Fast pH-Responsive Drug Release

    • Hua-Fen Wang
    • Hui-Zhen Jia
    • Ren-Xi Zhuo

    Research Paper 21 January 2012 Pages: 1582 - 1594

    

15. Tanshinones from Chinese Medicinal Herb Danshen (Salvia miltiorrhiza Bunge) Suppress Prostate Cancer Growth and Androgen Receptor Signaling

    • Yong Zhang
    • Suk-Hyun Won
    • Junxuan Lü

    Research Paper 27 January 2012 Pages: 1595 - 1608

    

16. Leveraging Physiological Data from Literature into a Pharmacokinetic Model to Support Informative Clinical Study Design in Pregnant Women

    • J. G. Coen van Hasselt
    • Bruce Green
    • Glynn A. Morrish

    Research Paper 13 January 2012 Pages: 1609 - 1617

    

17. Erythropoietin-Coated ZP-Microneedle Transdermal System: Preclinical Formulation, Stability, and Delivery

    • Elaine E. Peters
    • Mahmoud Ameri
    • Peter E. Daddona

    Research Paper 19 January 2012 Pages: 1618 - 1626

    

18. Efficient siRNA Delivery Using a Polyamidoamine Dendrimer with a Modified Pentaerythritol Core

    • Yue Zhang
    • Chenguang Zhou
    • Robert J. Lee

    Research Paper 25 January 2012 Pages: 1627 - 1636

    

19. Multi-Compartmental Nanoparticles-in-Emulsion Formulation for Macrophage-Specific Anti-Inflammatory Gene Delivery

    • Husain Attarwala
    • Mansoor Amiji

    Research Paper 27 January 2012 Pages: 1637 - 1649

    

20. A Nebulized Gelatin Nanoparticle-Based CpG Formulation is Effective in Immunotherapy of Allergic Horses

    • John Klier
    • Sebastian Fuchs
    • Conrad Coester

    Research Paper 03 February 2012 Pages: 1650 - 1657

    

21. Hepatocellular Necrosis, Fibrosis and Microsomal Activity Determine the Hepatic Pharmacokinetics of Basic Drugs in Right-Heart-Failure-Induced Liver Damage

    • Peng Li
    • Thomas A. Robertson
    • Michael S. Roberts

    Research Paper 01 February 2012 Pages: 1658 - 1669

    

22. Comparing MDI and DPI Aerosol Deposition Using In Vitro Experiments and a New Stochastic Individual Path (SIP) Model of the Conducting Airways

    • P. Worth Longest
    • Geng Tian
    • Michael Hindle

    Research Paper 31 January 2012 Pages: 1670 - 1688

    

23. Mechanistic Understanding of Protein-Silicone Oil Interactions

    • Jinjiang Li
    • Swathi Pinnamaneni
    • Xiaochun Zhang

    Research Paper 14 February 2012 Pages: 1689 - 1697

    

24. Human Pancreatic Polypeptide in a Phospholipid-Based Micellar Formulation

    • Amrita Banerjee
    • Hayat Onyuksel

    Research Paper 08 March 2012 Pages: 1698 - 1711

    

25. Erratum to: Human Pancreatic Polypeptide in a Phospholipid Based Micellar Formulation

    • Amrita Banerjee
    • Hayat Onyuksel

    Erratum 27 March 2012 Pages: 1712 - 1712

26. News

    News 03 April 2012 Pages: 1713 - 1715