1. Particle Engineering for Pulmonary Drug Delivery

   • Albert H. L. Chow
   • Henry H. Y. Tong
   • Boris Y. Shekunov

   Expert Review 24 January 2007 Pages: 411 - 437

   

2. Lipid-based Nanoparticles for Nucleic Acid Delivery

   • Weijun Li
   • Francis C. Szoka Jr.

   Expert Review 25 January 2007 Pages: 438 - 449

   

3. Organic Anion Transporters of the SLC22 Family: Biopharmaceutical, Physiological, and Pathological Roles

   • Ahsan N. Rizwan
   • Gerhard Burckhardt

   Expert Review 24 January 2007 Pages: 450 - 470

   

4. Best Practices for Managing Quality and Safety of Foreign Particles in Orally Inhaled and Nasal Drug Products, and an Evaluation of Clinical Relevance

   • James Blanchard
   • James Coleman
   • Ronald Wolff

   Commentary 25 January 2007 Pages: 471 - 479

   

5. Predicting the Oxidative Metabolism of Statins: An Application of the MetaSite® Algorithm

   • Giulia Caron
   • Giuseppe Ermondi
   • Bernard Testa

   Research Paper 26 January 2007 Pages: 480 - 501

   

6. Interplay of Secondary Structure and Charge on the Diffusion of a Polypeptide through Negatively Charged Aqueous Pores

   • Montakarn Chittchang
   • Ashim K. Mitra
   • Thomas P. Johnston

   Research Paper 24 January 2007 Pages: 502 - 511

   

7. Characterization of the Physiological Spaces and Distribution of Tolbutamide in the Perfused Rat Pancreas

   • Kent John Fanning
   • Michael S. Roberts

   Research Paper 25 January 2007 Pages: 512 - 520

   

8. Enhanced Release of Indomethacin from PVP/Stearic Acid Microcapsules Prepared Coupling Co-freeze-drying and Ultrasound Assisted Spray-congealing Process

   • Cristina Cavallari
   • Barbara Luppi
   • Adamo Fini

   Research Paper 25 January 2007 Pages: 521 - 529

   

9. Solubility-Excipient Classification Gradient Maps

   • Alex Avdeef
   • Stefanie Bendels
   • Manfred Kansy

   Research Paper 24 January 2007 Pages: 530 - 545

   

10. Intestinal Absorption of Miltefosine: Contribution of Passive Paracellular Transport

    • Cécile Ménez
    • Marion Buyse
    • Gillian Barratt

    Research Paper 25 January 2007 Pages: 546 - 554

    

11. Paclitaxel-2′-Ethylcarbonate Prodrug Can Circumvent P-glycoprotein-mediated Cellular Efflux to Increase Drug Cytotoxicity

    • Tadatoshi Tanino
    • Akihiro Nawa
    • Masahiro Iwaki

    Research Paper 24 January 2007 Pages: 555 - 565

    

12. Targeting 15d-Prostaglandin J₂ to Hepatic Stellate Cells: Two Options Evaluated

    • Werner I. Hagens
    • Adriana Mattos
    • Leonie Beljaars

    Research Paper Open access 24 January 2007 Pages: 566 - 574

    

13. Transport of Nicotinate and Structurally Related Compounds by Human SMCT1 (SLC5A8) and Its Relevance to Drug Transport in the Mammalian Intestinal Tract

    • Elangovan Gopal
    • Seiji Miyauchi
    • Vadivel Ganapathy

    Research Paper 24 January 2007 Pages: 575 - 584

    

14. Comparative Evaluation of Ibuprofen/β-Cyclodextrin Complexes Obtained by Supercritical Carbon Dioxide and Other Conventional Methods

    • Khaled Hussein
    • Michael Türk
    • Martin A. Wahl

    Research Paper 27 January 2007 Pages: 585 - 592

    

15. Glycine Crystallization in Frozen and Freeze-dried Systems: Effect of pH and Buffer Concentration

    • Dushyant B. Varshney
    • Satyendra Kumar
    • Raj Suryanarayanan

    Research Paper 24 January 2007 Pages: 593 - 604

    

16. Assessment of Performance of Manufacturing Procedures in a Unit for Production of Investigational Anticancer Agents, Using a Mixed Effects Analysis

    • S. C. van der Schoot
    • B. Nuijen
    • J. H. Beijnen

    Research Paper Open access 24 January 2007 Pages: 605 - 612

    

17. AAPS Update

    Announcement 31 January 2007 Pages: 613 - 614