1. Antiplatelet Drug Resistance and Drug-Drug Interactions: Role of Cytochrome P450 3A4

   • Wei C. Lau
   • Paul A. Gurbel

   Expert Review 24 October 2006 Pages: 2691 - 2708

   

2. A Review of Poloxamer 407 Pharmaceutical and Pharmacological Characteristics

   • Gilles Dumortier
   • Jean Louis Grossiord
   • Jean Claude Chaumeil

   Review Article 11 November 2006 Pages: 2709 - 2728

   

3. Design for Optimized Topical Delivery: Prodrugs and a Paradigm Change

   • Kenneth B. Sloan
   • Scott C. Wasdo
   • Jarkko Rautio

   Review Article 16 November 2006 Pages: 2729 - 2747

   

4. Performance of an Iterative Two-Stage Bayesian Technique for Population Pharmacokinetic Analysis of Rich Data Sets

   • Johannes H. Proost
   • Douglas J. Eleveld

   Research Paper 07 November 2006 Pages: 2748 - 2759

   

5. Fractal Michaelis-Menten Kinetics Under Steady State Conditions: Application to Mibefradil

   • Rebeccah E. Marsh
   • Jack A. Tuszyński

   Research Paper 25 October 2006 Pages: 2760 - 2767

   

6. Mechanisms Responsible for Poor Oral Bioavailability of Paeoniflorin: Role of Intestinal Disposition and Interactions with Sinomenine

   • Zhong Qiu Liu
   • Zhi Hong Jiang
   • Ming Hu

   Research Paper 25 October 2006 Pages: 2768 - 2780

   

7. Pharmacokinetics and Disposition of Memantine in the Arterially Perfused Bovine Eye

   • Martin J. Koeberle
   • Patrick M. Hughes
   • Clive G. Wilson

   Research Paper 14 November 2006 Pages: 2781 - 2798

   

8. Transition Metal-Mediated Liposomal Encapsulation of Irinotecan (CPT-11) Stabilizes the Drug in the Therapeutically Active Lactone Conformation

   • Euan Ramsay
   • Jehan Alnajim
   • Marcel Bally

   Research Paper 25 October 2006 Pages: 2799 - 2808

   

9. Development of 5-FU and Doxorubicin-Loaded Cationic Liposomes against Human Pancreatic Cancer: Implications for Tumor Vascular Targeting

   • Ashish V. Kalra
   • Robert B. Campbell

   Research Paper 26 October 2006 Pages: 2809 - 2817

   

10. Transport of Poly(Amidoamine) Dendrimers across Caco-2 Cell Monolayers: Influence of Size, Charge and Fluorescent Labeling

    • Kelly M. Kitchens
    • Rohit B. Kolhatkar
    • Hamidreza Ghandehari

    Research Paper 09 November 2006 Pages: 2818 - 2826

    

11. New Safe Method for Preparation of Sarin-Exposed Human Erythrocytes Acetylcholinesterase Using Non-Toxic and Stable Sarin Analogue Isopropyl p-Nitrophenyl Methylphosphonate and its Application to Evaluation of Nerve Agent Antidotes

    • Hikoto Ohta
    • Takeshi Ohmori
    • Takehiko Takatori

    Research Paper 10 November 2006 Pages: 2827 - 2833

    

12. AAPS Update

    Announcement 16 November 2006 Pages: 2834 - 2835