1. Polymer Architecture and Drug Delivery

   • Li Yan Qiu
   • You Han Bae

   Review Paper 11 January 2006 Pages: 1 - 30

   

2. Varying the Unsaturation in N⁴,N⁹-Dioctadecanoyl Spermines: Nonviral Lipopolyamine Vectors for More Efficient Plasmid DNA Formulation

   • Osama A. A. Ahmed
   • Charareh Pourzand
   • Ian S. Blagbrough

   Feature Article 31 December 2006 Pages: 31 - 40

   

3. Prediction of Milk/Plasma Drug Concentration (M/P) Ratio Using Support Vector Machine (SVM) Method

   • Chunyan Zhao
   • Haixia Zhang
   • Botao Fan

   Research Paper 30 November 2006 Pages: 41 - 48

   

4. Biochemical and Physiological Properties of a Novel Series of Long-Acting Insulin Analogs Obtained by Acylation with Cholic Acid Derivatives

   • Ib Jonassen
   • Svend Havelund
   • Jan Markussen

   Research Paper 21 December 2006 Pages: 49 - 55

   

5. Evaluation of Human Liver Slices and Reporter Gene Assays as Systems for Predicting the Cytochrome P450 Induction Potential of Drugs in Vivo in Humans

   • Kajsa P. Persson
   • Susanne Ekehed
   • Tommy B. Andersson

   Research Paper 22 November 2006 Pages: 56 - 69

   

6. Evaluation of Cancer-Preventive Activity and Structure–Activity Relationships of 3-Demethylubiquinone Q₂, Isolated from the Ascidian Aplidium glabrum, and its Synthetic Analogs

   • Sergey N. Fedorov
   • Oleg S. Radchenko
   • Zigang Dong

   Research Paper 05 December 2006 Pages: 70 - 81

   

7. Smad3 Specific Inhibitor, Naringenin, Decreases the Expression of Extracellular Matrix Induced by TGF-β1 in Cultured Rat Hepatic Stellate Cells

   • Xingjun Liu
   • Wei Wang
   • Minwei Wang

   Research Paper 14 December 2006 Pages: 82 - 89

   

8. R(+)-Methanandamide Elicits a Cyclooxygenase-2-Dependent Mitochondrial Apoptosis Signaling Pathway in Human Neuroglioma Cells

   • Karin Eichele
   • Ulrike Weinzierl
   • Burkhard Hinz

   Research Paper 08 November 2006 Pages: 90 - 94

   

9. Pharmacokinetics/Pharmacodynamics of Nondepleting Anti-CD4 Monoclonal Antibody (TRX1) in Healthy Human Volunteers

   • Chee M. Ng
   • Eric Stefanich
   • Louis Vaickus

   Research Paper 30 November 2006 Pages: 95 - 103

   

10. Microinfusion Using Hollow Microneedles

    • Wijaya Martanto
    • Jason S. Moore
    • Mark R. Prausnitz

    Research Paper 30 November 2006 Pages: 104 - 113

    

11. Transdermal Delivery of Heparin Using Pulsed Current Iontophoresis

    • Stefania Pacini
    • Tiziana Punzi
    • Marco Ruggiero

    Research Paper 21 December 2006 Pages: 114 - 120

    

12. New Cyclodextrin Hydrogels Cross-Linked with Diglycidylethers with a High Drug Loading and Controlled Release Ability

    • Carmen Rodriguez-Tenreiro
    • Carmen Alvarez-Lorenzo
    • Juan J. Torres-Labandeira

    Research Paper 07 December 2006 Pages: 121 - 130

    

13. Substrate Specificity and Mechanism of the Intestinal Clonidine Uptake by Caco-2 Cells

    • Wiebke Fischer
    • Linda Metzner
    • Matthias Brandsch

    Research Paper 13 December 2006 Pages: 131 - 137

    

14. Inhaled Insulin is Better Absorbed When Administered as a Dry Powder Compared to Solution in the Presence or Absence of Alkylglycosides

    • Alamdar Hussain
    • Quamrul H. Majumder
    • Fakhrul Ahsan

    Research Paper 07 December 2006 Pages: 138 - 147

    

15. Kinetics of Insulin Adsorption at the Oil–Water Interface and Diffusion Properties of Adsorbed Layers Monitored Using Fluorescence Correlation Spectroscopy

    • Jesper Donsmark
    • Lene Jorgensen
    • Christian Rischel

    Research Paper 30 November 2006 Pages: 148 - 155

    

16. Analytical Studies on the Prediction of Photosensitive/Phototoxic Potential of Pharmaceutical Substances

    • Satomi Onoue
    • Yoshiko Tsuda

    Research Paper 30 November 2006 Pages: 156 - 164

    

17. Characterization of the Human Upper Gastrointestinal Contents Under Conditions Simulating Bioavailability/Bioequivalence Studies

    • Lida Kalantzi
    • Konstantinos Goumas
    • Christos Reppas

    Research Paper 01 December 2006 Pages: 165 - 176

    

18. Preparation of Polymeric Submicron Particle-Containing Microparticles Using a 4-Fluid Nozzle Spray Drier

    • Tetsuya Ozeki
    • Shuji Beppu
    • Hiroaki Okada

    Research Paper 08 November 2006 Pages: 177 - 183

    

19. Design of Estradiol Loaded PLGA Nanoparticulate Formulations: A Potential Oral Delivery System for Hormone Therapy

    • S. Hariharan
    • V. Bhardwaj
    • M. N. V. Ravi Kumar

    Research Paper 08 November 2006 Pages: 184 - 195

    

20. Nanoparticles of Poorly Water-Soluble Drugs Prepared by Supercritical Fluid Extraction of Emulsions

    • Boris Y. Shekunov
    • Pratibhash Chattopadhyay
    • Robert Huff

    Research Paper 30 November 2006 Pages: 196 - 204

    

21. Thermoresponsive Gelatin/Monomethoxy Poly(Ethylene Glycol)–Poly(d,l-lactide) Hydrogels: Formulation, Characterization, and Antibacterial Drug Delivery

    • Hu Yang
    • Weiyuan John Kao

    Research Paper 08 November 2006 Pages: 205 - 214

    

22. Effect of Polymer Blending on the Release of Ganciclovir from PLGA Microspheres

    • Sridhar Duvvuri
    • Kumar Gaurav Janoria
    • Ashim K. Mitra

    Research Paper 06 December 2006 Pages: 215 - 223

    

23. AAPS Update

    OriginalPaper 13 January 2006 Pages: 224 - 225