1. Method Validation and Measurement of Biomarkers in Nonclinical and Clinical Samples in Drug Development: A Conference Report

   • Jean W. Lee
   • Russ S. Weiner
   • John A. Wagner

   Conference Report 07 April 2005 Pages: 499 - 511

2. In Vitro and Pharmacophore-Based Discovery of Novel hPEPT1 Inhibitors

   • Sean Ekins
   • Jeffrey S. Johnston
   • Peter W. Swaan

   Rapid Communications 07 April 2005 Pages: 512 - 517

3. Micrometer-Scale Particle Sizing by Laser Diffraction: Critical Impact of the Imaginary Component of Refractive Index

   • Alice Beekman
   • Daxian Shan
   • Merrill Goldenberg

   Rapid Communications 07 April 2005 Pages: 518 - 522

4. Data Supplementation: A Pharmacokinetic/Pharmacodynamic Knowledge Creation Approach for Characterizing an Unexplored Region of the Response Surface

   • Ene I. Ette
   • Hui-May Chu
   • Christopher J. Godfrey

   Research Papers 07 April 2005 Pages: 523 - 531

5. A Population Pharmacokinetic Model for Montelukast Disposition in Adults and Children

   • Rohini Ramakrishnan
   • Elizabeth Migoya
   • Barbara Knorr

   Research Papers 07 April 2005 Pages: 532 - 540

6. Covariate Detection in Population Pharmacokinetics Using Partially Linear Mixed Effects Models

   • Peter L. Bonate

   Research Papers 07 April 2005 Pages: 541 - 549

7. Transdermal Delivery of Human Growth Hormone Through RF-Microchannels

   • Galit Levin
   • Amikam Gershonowitz
   • Moshe Phillip

   Research Papers 07 April 2005 Pages: 550 - 555

8. Nipecotic Acid: Systemic Availability and Brain Delivery After Nasal Administration of Nipecotic Acid and n-Butyl Nipecotate to Rats

   • Hongna Wang
   • Anwar A. Hussain
   • Peter J. Wedlund

   Research Papers 07 April 2005 Pages: 556 - 562

9. Local Delivery of Vancomycin for the Prophylaxis of Prosthetic Device-Related Infections

   • Dakshina M. Chilukuri
   • Jaymin C. Shah

   Research Papers 07 April 2005 Pages: 563 - 572

10. Lyophilized Paclitaxel Magnetoliposomes as a Potential Drug Delivery System for Breast Carcinoma via Parenteral Administration: In Vitro and in Vivo Studies

    • J. Q. Zhang
    • Z. R. Zhang
    • X. L. Qiu

    Research Papers 07 April 2005 Pages: 573 - 583

11. Development and Characterization of Bioadhesive Vaginal Films of Sodium Polystyrene Sulfonate (PSS), a Novel Contraceptive Antimicrobial Agent

    • Sanjay Garg
    • Kavita Vermani
    • Lourens J. D. Zaneveld

    Research Papers 07 April 2005 Pages: 584 - 595

12. Pharmacokinetics and Tissue Retention of (Gd-DTPA)-Cystamine Copolymers, a Biodegradable Macromolecular Magnetic Resonance Imaging Contrast Agent

    • Xinghe Wang
    • Yi Feng
    • Zheng-Rong Lu

    Research Papers 07 April 2005 Pages: 596 - 602

13. Pharmacodynamic Assessment of the Benztropine Analogues AHN-1055 and AHN-2005 Using Intracerebral Microdialysis to Evaluate Brain Dopamine Levels and Pharmacokinetic/Pharmacodynamic Modeling

    • Sangeeta Raje
    • Jennifer Cornish
    • Natalie D. Eddington

    Research Papers 07 April 2005 Pages: 603 - 612

14. Lack of Improvement of Oral Absorption of ME3277 by Prodrug Formation Is Ascribed to the Intestinal Efflux Mediated by Breast Cancer Resistant Protein (BCRP/ABCG2)

    • Chihiro Kondo
    • Reiko Onuki
    • Yuichi Sugiyama

    Research Papers 07 April 2005 Pages: 613 - 618

15. Differential Contributions of rOat1 (Slc22a6) and rOat3 (Slc22a8) to the in Vivo Renal Uptake of Uremic Toxins in Rats

    • Tsuneo Deguchi
    • Yousuke Kouno
    • Masaki Otagiri

    Research Papers 07 April 2005 Pages: 619 - 627

16. Investigation of Solubility and Dissolution of a Free Base and Two Different Salt Forms as a Function of pH

    • Shoufeng Li
    • SuiMing Wong
    • Abu T. M. Serajuddin

    Research Papers 07 April 2005 Pages: 628 - 635

17. A Natural Compound (Ginsenoside Re) Isolated from Panax ginseng as a Novel Angiogenic Agent for Tissue Regeneration

    • Ya-Chun Huang
    • Chiung-Tong Chen
    • Hsing-Wen Sung

    Research Papers 07 April 2005 Pages: 636 - 646

18. Molecular Cloning and Functional Analyses of OAT1 and OAT3 from Cynomolgus Monkey Kidney

    • Harunobu Tahara
    • Masayuki Shono
    • Yuichi Sugiyama

    Research Papers 07 April 2005 Pages: 647 - 660

19. Treatment of Hyperbilirubinemia in Eisai Hyperbilirubinemic Rat by Transfecting Human MRP2/ABCC2 Gene

    • Masakazu Hirouchi
    • Hiroshi Suzuki
    • Yuichi Sugiyama

    Research Papers 07 April 2005 Pages: 661 - 666

20. High-Performance Frontal Analysis of the Binding of Thyroxine Enantiomers to Human Serum Albumin Binding of Thyroxine Enantiomers to Human Serum Albumin Kimura

    • Tomoko Kimura
    • Keiko Nakanishi
    • Katsumi Matsuzaki

    Research Papers 07 April 2005 Pages: 667 - 675

21. Development of Novel Nonaqueous Ethylcellulose Gel Matrices: Rheological and Mechanical Characterization

    • P. W. S. Heng
    • L. W. Chan
    • K. T. Chow

    Research Papers 07 April 2005 Pages: 676 - 684

22. Freeze-Drying Process Design by Manometric Temperature Measurement: Design of a Smart Freeze-Dryer

    • Xiaolin (Charlie) Tang
    • Steven L. Nail
    • Michael J. Pikal

    Research Papers 07 April 2005 Pages: 685 - 700

23. AAPS Update

    Conference 07 April 2005 Pages: 701 - 702