1. Polyethylene Glycol-Conjugated Copolymers for Plasmid DNA Delivery

   • Minhyung Lee
   • Sung Wan Kim

   ReviewPaper 01 January 2005 Pages: 1 - 10

2. Predicting Drug Disposition via Application of BCS: Transport/Absorption/ Elimination Interplay and Development of a Biopharmaceutics Drug Disposition Classification System

   • Chi-Yuan Wu
   • Leslie Z. Benet

   OriginalPaper 01 January 2005 Pages: 11 - 23

3. Polymeric Micelles Based on Amphiphilic Scorpion-like Macromolecules: Novel Carriers for Water-Insoluble Drugs

   • Jelena Djordjevic
   • Maryan Barch
   • Kathryn E. Uhrich

   OriginalPaper 01 January 2005 Pages: 24 - 32

4. Concentration Determination of a Recombinant Vaccine Antigen Adsorbed onto an Alum Adjuvant by Chemiluminescent Nitrogen Detection

   • John V. Amari
   • Philip Levesque
   • Uditha deAlwis

   OriginalPaper 01 January 2005 Pages: 33 - 37

5. In Vitro and ex Vivo Intestinal Tissue Models to Measure Mucoadhesion of Poly (Methacrylate) and N-Trimethylated Chitosan Polymers

   • Simon Keely
   • Atvinder Rullay
   • David J. Brayden

   OriginalPaper 01 January 2005 Pages: 38 - 49

6. Vitamin D₃–Based Conjugates for Topical Treatment of Psoriasis: Synthesis, Antiproliferative Activity, and Cutaneous Penetration Studies

   • Shimon Ben-Shabat
   • Rachel Benisty
   • Amnon C. Sintov

   OriginalPaper 01 January 2005 Pages: 50 - 57

7. Pharmacokinetics and Pharmacodynamics of PEGylated IFN-β 1a Following Subcutaneous Administration in Monkeys

   • Donald E. Mager
   • Berend Neuteboom
   • William J. Jusko

   OriginalPaper 01 January 2005 Pages: 58 - 61

8. Selective Downregulation of Hepatic Cytochrome P450 Expression and Activity in a Rat Model of Inflammatory Pain

   • Denis Projean
   • Sophie Dautrey
   • Julie Ducharme

   OriginalPaper 01 January 2005 Pages: 62 - 70

9. Comparative Effects of Fibrates on Drug Metabolizing Enzymes in Human Hepatocytes

   • Thomayant Prueksaritanont
   • Karen M. Richards
   • Edward J. Carlini

   OriginalPaper 01 January 2005 Pages: 71 - 78

10. Stereoselective Taurine Conjugation of (R)-Benoxaprofen Enantiomer in Rats: In Vivo and in Vitro Studies Using Rat Hepatic Mitochondria and Microsomes

    • Kiminori Mohri
    • Kenji Okada
    • Leslie Z. Benet

    OriginalPaper 01 January 2005 Pages: 79 - 85

11. Functional Evidence for P-glycoprotein at the Nose-Brain Barrier

    • Candace L. Graff
    • Gary M. Pollack

    OriginalPaper 01 January 2005 Pages: 86 - 93

12. Estimation of Transdermal Permeation Parameters in Non-stationary Diffusion Experiments. Application to Pre-treatment Studies with Terpenes

    • A. Boix
    • C. Peraire
    • J. Domenech

    OriginalPaper 01 January 2005 Pages: 94 - 102

13. Prediction of Human Drug Clearance from in Vitro and Preclinical Data Using Physiologically Based and Empirical Approaches

    • Kiyomi Ito
    • J. Brian Houston

    OriginalPaper 01 January 2005 Pages: 103 - 112

14. A Fluorometric Screening Assay for Drug Efflux Transporter Activity in the Blood-Brain Barrier

    • Corbin J. Bachmeier
    • Donald W. Miller

    OriginalPaper 01 January 2005 Pages: 113 - 121

15. Antibodies as Drug Carriers III: Design of Oligonucleotides with Enhanced Binding Affinity for Immunoglobulin G

    • Enzo Palma
    • David G. Klapper
    • M. J. Cho

    OriginalPaper 01 January 2005 Pages: 122 - 127

16. The Effect of Inert Atmospheric Packaging on Oxidative Degradation in Formulated Granules

    • Rajiv Mahajan
    • Allen Templeton
    • Rey T. Chern

    OriginalPaper 01 January 2005 Pages: 128 - 140

17. Effects of Excipients on the Hydrogen Peroxide-Induced Oxidation of Methionine Residues in Granulocyte Colony-Stimulating Factor

    • Jin Yin
    • Jhih-Wei Chu
    • Bernhardt L. Trout

    OriginalPaper 01 January 2005 Pages: 141 - 147

18. How Much Particle Surface Corrugation Is Sufficient to Improve Aerosol Performance of Powders?

    • Nora Y. K. Chew
    • Patricia Tang
    • Judy A. Raper

    OriginalPaper 01 January 2005 Pages: 148 - 152

19. Crystallization of Cephalothin Sodium During Lyophilization from tert-Butyl Alcohol—Water Cosolvent System

    • Chitra Telang
    • Raj Suryanarayanan

    OriginalPaper 01 January 2005 Pages: 153 - 160

20. Mensuration and Cleaning of the Jets in Andersen Cascade Impactors

    • Mårten Svensson
    • Gunilla Pettersson
    • Lars Asking

    OriginalPaper 01 January 2005 Pages: 161 - 165

21. Suitability of the Upper Airway Models Obtained from MRI Studies in Simulating Drug Lung Deposition from Inhalers

    • T. Ehtezazi
    • K. W. Southern
    • C. O’Callaghan

    OriginalPaper 01 January 2005 Pages: 166 - 170

22. AAPS Update

    Announcement 01 January 2005 Pages: 171 - 172