1. Preface: A Tribute to Prof. John B. Clark

   • Anna Maria Giuffrida-Stella

   Preface Pages: 481 - 482

2. Mitochondrial Disease: A Historical, Biochemical, and London Perspective

   • John M. Land
   • John A. Morgan-Hughes
   • Simon J. R. Heales

   OriginalPaper Pages: 483 - 491

3. Mitochondrial Dysfunction in Neurodegenerative Diseases Associated with Copper Imbalance

   • Luisa Rossi
   • Marco F. Lombardo
   • Giuseppe Rotilio

   OriginalPaper Pages: 493 - 504

4. Neuropathological Aspects of Mitochondrial DNA Disease

   • Joanne Betts
   • Robert N. Lightowlers
   • Douglass M. Turnbull

   OriginalPaper Pages: 505 - 511

5. Neurodegeneration or Neuroprotection: The Pivotal Role of Astrocytes

   • Simon J. R. Heales
   • Amanda A. J. Lam
   • John M. Land

   OriginalPaper Pages: 513 - 519

6. Mitochondrial Function in Apoptotic Neuronal Cell Death

   • Samantha L. Budd Haeberlein

   OriginalPaper Pages: 521 - 530

7. The Energetics of Huntington's Disease

   • Susan E. Browne
   • M. Flint Beal

   OriginalPaper Pages: 531 - 546

8. Respiratory Complex I in Brain Development and Genetic Disease

   • Sergio Papa
   • Vittoria Petruzzella
   • Filippo Maria Santorelli

   OriginalPaper Pages: 547 - 560

9. Role of Oxidative Damage in Friedreich's Ataxia

   • J. L. Bradley
   • S. Homayoun
   • J. M. Cooper

   OriginalPaper Pages: 561 - 567

10. Initiation of Neuronal Damage by Complex I Deficiency and Oxidative Stress in Parkinson's Disease

    • Laszlo Tretter
    • Ildiko Sipos
    • Vera Adam-Vizi

    OriginalPaper Pages: 569 - 577

11. Peroxynitrite Mediates Nitric Oxide–Induced Blood–Brain Barrier Damage

    • Kian H. Tan
    • Sian Harrington
    • Roger D. Hurst

    OriginalPaper Pages: 579 - 587

12. Mitochondrial Disease: Mutations and Mechanisms

    • Matthew McKenzie
    • Danae Liolitsa
    • Michael G. Hanna

    OriginalPaper Pages: 589 - 600

13. Astrocyte Mitochondrial Mechanisms of Ischemic Brain Injury and Neuroprotection

    • Linda Bambrick
    • Tibor Kristian
    • Gary Fiskum

    OriginalPaper Pages: 601 - 608

14. Increased Mitochondrial Permeability in Response to Intrastriatal N-Methyl-d-Aspartate: Detection Based on Accumulation of Radiolabel from [³H]Deoxyglucose

    • Emad Zaidan
    • Michael Nilsson
    • Neil R. Sims

    OriginalPaper Pages: 609 - 616

15. Redox Control of Signal Transduction, Gene Expression and Cellular Senescence

    • Franca Esposito
    • Rosario Ammendola
    • Filiberto Cimino

    OriginalPaper Pages: 617 - 628

16. Substantial Linkage Disequilibrium Across the Dihydrolipoyl Succinyltransferase Gene Region Without Alzheimer's Disease Association

    • Abraham M. Brown
    • Derek Gordon
    • John P. Blass

    OriginalPaper Pages: 629 - 635

17. Toxicity of Amyloid β Peptide: Tales of Calcium, Mitochondria, and Oxidative Stress

    • Laura Canevari
    • Andrey Y. Abramov
    • Michael R. Duchen

    OriginalPaper Pages: 637 - 650

18. Mitochondrial Heterogeneity Within and Between Different Cell Types

    • Hsueh-Meei Huang
    • Corinne Fowler
    • Gary E. Gibson

    OriginalPaper Pages: 651 - 658