Volume 39, Issue 10 | Neurochemical Research

Search all Neurochemical Research articles

Volume 39, Issue 10

October 2014

Special Issue in Honor of Povl Krogsgaard-Larsen

Issue Editors:

HANS BRÄUNER-OSBORNE,
ARNE SCHOUSBOE

17 articles in this issue

Introduction to Special Issue in Honor of Professor Povl Krogsgaard-Larsen
Hans Bräuner-Osborne
Arne Schousboe
Preface 26 August 2014 Pages: 1845 - 1846
Povl Krogsgaard-Larsen: A Giant in Medicinal Chemistry Research
Klaus P. Bøgesø
Commentary 18 September 2014 Pages: 1847 - 1849
The Receptor Concept in 3D: From Hypothesis and Metaphor to GPCR–Ligand Structures
Albert J. Kooistra
Chris de Graaf
Henk Timmerman
Overview 08 August 2014 Pages: 1850 - 1861
mGluR5: Exploration of Orthosteric and Allosteric Ligand Binding Pockets and Their Applications to Drug Discovery
Christina Mølck
Kasper Harpsøe
Hans Bräuner-Osborne
Overview 04 February 2014 Pages: 1862 - 1875
Group III Metabotropic Glutamate Receptors: Pharmacology, Physiology and Therapeutic Potential
Marion S. Mercier
David Lodge
Overview 22 August 2014 Pages: 1876 - 1894
Analogues of 3-Hydroxyisoxazole-Containing Glutamate Receptor Ligands Based on the 3-Hydroxypyrazole-Moiety: Design, Synthesis and Pharmacological Characterization
Lars Jørgensen
Birgitte Nielsen
Rasmus P. Clausen
Original Paper 22 May 2014 Pages: 1895 - 1905
Inhibition of AMPA Receptors by Polyamine Toxins is Regulated by Agonist Efficacy and Stargazin
Mette H. Poulsen
Simon Lucas
Anders S. Kristensen
Original Paper 22 February 2014 Pages: 1906 - 1913
Multi-target Design Strategies in the Context of Alzheimer’s Disease: Acetylcholinesterase Inhibition and NMDA Receptor Antagonism as the Driving Forces
Michela Rosini
Elena Simoni
Carlo Melchiorre
Overview 04 February 2014 Pages: 1914 - 1923
Analysis of γ-Aminobutyric Acid (GABA) Type A Receptor Subtypes Using Isosteric and Allosteric Ligands
Richard W. Olsen
Overview 12 July 2014 Pages: 1924 - 1941
Muscimol as an Ionotropic GABA Receptor Agonist
Graham A. R. Johnston
Overview 29 January 2014 Pages: 1942 - 1947
GABA Pharmacology: The Search for Analgesics
Kenneth E. McCarson
S. J. Enna
Overview 15 February 2014 Pages: 1948 - 1963
Probing for Improved Potency and In Vivo Bioavailability of Excitatory Amino Acid Transporter Subtype 1 Inhibitors UCPH-101 and UCPH-102: Design, Synthesis and Pharmacological Evaluation of Substituted 7-Biphenyl Analogs
Mette N. Erichsen
Jeanette Hansen
Lennart Bunch
Original Paper 28 February 2014 Pages: 1964 - 1979
The GABA Synapse as a Target for Antiepileptic Drugs: A Historical Overview Focused on GABA Transporters
Arne Schousboe
Karsten K. Madsen
H. Steve White
Overview 14 March 2014 Pages: 1980 - 1987
Pharmacological Identification of a Guanidine-Containing β-Alanine Analogue with Low Micromolar Potency and Selectivity for the Betaine/GABA Transporter 1 (BGT1)
Anas Al-Khawaja
Jette G. Petersen
Petrine Wellendorph
Original Paper 23 May 2014 Pages: 1988 - 1996
Revision of the Classical Dopamine D₂ Agonist Pharmacophore Based on an Integrated Medicinal Chemistry, Homology Modelling and Computational Docking Approach
N. Krogsgaard-Larsen
K. Harpsøe
T. Balle
Original Paper 24 July 2014 Pages: 1997 - 2007
On the Discovery and Development of Pimavanserin: A Novel Drug Candidate for Parkinson’s Psychosis
Uli Hacksell
Ethan S. Burstein
Hilde Williams
Overview Open access 30 March 2014 Pages: 2008 - 2017
Correlating the Metabolic Stability of Psychedelic 5-HT_2A Agonists with Anecdotal Reports of Human Oral Bioavailability
Sebastian Leth-Petersen
Christoffer Bundgaard
Jesper Langgaard Kristensen
Original Paper 12 February 2014 Pages: 2018 - 2023