1. Novel strategies for cancer therapy

   • Gregg L. Semenza

   Editorial 16 January 2016 Pages: 119 - 120

2. Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets

   • Matthias Drosten
   • Mariano Barbacid

   Review 03 November 2015 Pages: 121 - 135

   

3. Glycogen metabolism has a key role in the cancer microenvironment and provides new targets for cancer therapy

   • Christos E. Zois
   • Adrian L. Harris

   Review Open access 17 February 2016 Pages: 137 - 154

   

4. Hypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H⁺ symporters

   • Ibtissam Marchiq
   • Jacques Pouysségur

   Review Open access 24 June 2015 Pages: 155 - 171

   

5. Regulation and function of SIRT1 in rheumatoid arthritis synovial fibroblasts

   • Anna Engler
   • Clare Tange
   • Caroline Ospelt

   Original Article 23 August 2015 Pages: 173 - 182

   

6. Inhibition of AMPK through Lyn-Syk-Akt enhances FcεRI signal pathways for allergic response

   • Kai-Chun Lin
   • Duen-Yi Huang
   • Wan-Wan Lin

   Original Article 16 September 2015 Pages: 183 - 194

   

7. Isoliquiritigenin prevents the progression of psoriasis-like symptoms by inhibiting NF-κB and proinflammatory cytokines

   • Yangping Wu
   • Xiangzheng Chen
   • Jinliang Yang

   Original Article 18 September 2015 Pages: 195 - 206

   

8. Vaccination against type 1 angiotensin receptor prevents streptozotocin-induced diabetic nephropathy

   • Dan Ding
   • Yimei Du
   • Xiao Chen

   Original Article Open access 26 September 2015 Pages: 207 - 218

   

9. Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation

   • Ismael Secundino
   • Anel Lizcano
   • Victor Nizet

   Original Article 28 September 2015 Pages: 219 - 233

   

10. Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington’s disease models

    • Joshua L. Smalley
    • Carlo Breda
    • Flaviano Giorgini

    Original Article Open access 02 October 2015 Pages: 235 - 245