1. Foreword

   • Marten Wikström

   Foreword Pages: 3 - 5

2. Crystal Structure of Bovine Heart Cytochrome c Oxidase at 2.8 Å Resolution

   • Shinya Yoshikawa
   • Kyoko Shinzawa-Itoh
   • Tomitake Tsukihara

   OriginalPaper Pages: 7 - 14

3. From NO to OO: Nitric Oxide and Dioxygen in Bacterial Respiration

   • Janneke Hendriks
   • Ulrich Gohlke
   • Matti Saraste

   OriginalPaper Pages: 15 - 24

4. Regulation of Energy Transduction and Electron Transfer in Cytochrome c Oxidase by Adenine Nucleotides

   • Bernhard Kadenbach
   • Jörg Napiwotzki
   • Maik Hüttemann

   OriginalPaper Pages: 25 - 33

5. Pathways for Electron Tunneling in Cytochrome c Oxidase

   • Jeffrey J. Regan
   • Benjamin E. Ramirez
   • Bo G. Malmström

   OriginalPaper Pages: 35 - 39

6. Investigating the Mechanism of Electron Transfer to the Binuclear Center in Cu-Heme Oxidases

   • M. Brunori
   • A. Giuffré
   • P. Sarti

   OriginalPaper Pages: 41 - 45

7. Determination and Novel Features of the Absolute Absorption Spectra of the Heme a Moieties in Cytochrome c Oxidase

   • Yutaka Orii

   OriginalPaper Pages: 47 - 53

8. The Dinuclear Center of Cytochrome bo ₃ from Escherichia coli

   • Nicholas J. Watmough
   • Myles R. Cheesman
   • Andrew J. Thomson

   OriginalPaper Pages: 55 - 62

9. Reactivity of Nitric Oxide with Cytochrome c Oxidase: Interactions with the Binuclear Centre and Mechanism of Inhibition

   • Jaume Torres
   • Chris E. Cooper
   • Michael T. Wilson

   OriginalPaper Pages: 63 - 69

10. Time-Resolved Resonance Raman Investigation of Oxygen Reduction Mechanism of Bovine Cytochrome c Oxidase

    • Teizo Kitagawa
    • Takashi Ogura

    OriginalPaper Pages: 71 - 79

11. The Role of Electrostatic Interactions for Cytochrome c Oxidase Function

    • Aimo Kannt
    • C. Roy D. Lancaster
    • Hartmut Michel

    OriginalPaper Pages: 81 - 87

12. Cytochrome c Oxidase (Heme aa ₃) from Paracoccus denitrificans: Analysis of Mutations in Putative Proton Channels of Subunit I

    • Ute Pfitzner
    • Annette Odenwald
    • Oliver-Matthias H. Richter

    OriginalPaper Pages: 89 - 97

13. Pathways of Proton Transfer in Cytochrome c Oxidase

    • Peter Brzezinski
    • Pia Ädelroth

    OriginalPaper Pages: 99 - 107

14. Redox Bohr Effects (Cooperative Coupling) and the Role of Heme a in the Proton Pump of Cytochrome c Oxidase

    • Sergio Papa
    • Nazzareno Capitanio

    OriginalPaper Pages: 109 - 119

15. Cytochrome c Oxidase as a Proton-Pumping Peroxidase: Reaction Cycle and Electrogenic Mechanism

    • Alexander A. Konstantinov

    OriginalPaper Pages: 121 - 130

16. Protonmotive Mechanism of Heme-Copper Oxidases

    • P. R. Rich
    • S. Jünemann
    • B. Meunier

    OriginalPaper Pages: 131 - 138

17. On the Mechanism of Proton Translocation by Respiratory Enzyme

    • Mårten Wikström
    • Joel E. Morgan
    • Michael I. Verkhovsky

    OriginalPaper Pages: 139 - 145