Volume 46, Issue 1

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February 2023

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33 articles in this issue

Neuroinflammation in Alzheimer’s Disease: Current Progress in Molecular Signaling and Therapeutics
Sujata Thakur
Rishika Dhapola
Dibbanti HariKrishna Reddy
Review 20 August 2022 Pages: 1 - 17
Structure Composition and Intracellular Transport of Clathrin-Mediated Intestinal Transmembrane Tight Junction Protein
Yi-Yang Pan
Ying Deng
Guang-Sheng Du
Review 01 September 2022 Pages: 18 - 34
NLRP3 Inflammasome in Atherosclerosis: Putting Out the Fire of Inflammation
Bo-Zong Shao
Hai-Yan Xu
Guan-Ren Zhao
Review 11 August 2022 Pages: 35 - 46
The Role of Macrophages and Alveolar Epithelial Cells in the Development of ARDS
Huan Tao
Younian Xu
Shihai Zhang
Review 01 September 2022 Pages: 47 - 55
Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer’s Disease: a Review of Mechanism of Activation, Regulation, and Inhibition
Barkha Sharma
Garvit Satija
Mohammad Ahmed Khan
Review 25 August 2022 Pages: 56 - 87
Role of T Cells in the Pathogenesis of Rheumatoid Arthritis: Focus on Immunometabolism Dysfunctions
Maryam Masoumi
Samira Alesaeidi
Jafar Karami
Review 10 October 2022 Pages: 88 - 102
Investigation of TLR4 Antagonists for Prevention of Intestinal Inflammation
Janine S. Y. Tam
Janet K. Coller
Joanne M. Bowen
Original Article Open access 22 July 2022 Pages: 103 - 114
PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways
Longxiang Huang
Yuanjing Li
Yong Xia
Original Article 05 August 2022 Pages: 115 - 128
Hyperglycemia Aggravates Blood–Brain Barrier Disruption Following Diffuse Axonal Injury by Increasing the Levels of Inflammatory Mediators through the PPARγ/Caveolin-1/TLR4 Pathway
Xing Wei
Yaqing Zhou
Yonglin Zhao
Original Article 20 July 2022 Pages: 129 - 145
The Pathogenic Role of Oxidative Stress, Cytokine Expression, and Impaired Hematological Indices in Diabetic Cardiovascular Diseases
Howaida Saad
Hanan A. Soliman
Mohamed Y. Zaky
Original Article Open access 23 August 2022 Pages: 146 - 160
Circ_0088194 Regulates Proliferation, Migration, Apoptosis, and Inflammation by miR-30a-3p/ADAM10 Axis in Rheumatoid Arthritis Fibroblastic Synovial Cells
Lei Feng
Wenseng Jing
Bo Wang
Original Article 02 August 2022 Pages: 161 - 174
Morin Augmented Myocardial eNOS/cGMP/PKG Signaling Pathway and Abated Oxidative and Inflammo-apoptotic Responses in Diethyl Phthalate and Bisphenol-S Co-Exposed Male Albino Rats
Adewale Segun James
Ofem Effiom Eteng
Regina Ngozi Ugbaja
Original Article 28 July 2022 Pages: 175 - 189
Anti-inflammatory Effect of a Limonin Derivative In Vivo and Its Mechanisms in RAW264.7 Cells
Ning Wang
Xiao Chen
Guoqing Gong
Original Article 20 August 2022 Pages: 190 - 201
Macrophage-Derived TGF-β and VEGF Promote the Progression of Trauma-Induced Heterotopic Ossification
Bing Tu
Juehong Li
Cunyi Fan
Original Article 20 August 2022 Pages: 202 - 216
Convergence of Fructose-Induced NLRP3 Activation with Oxidative Stress and ER Stress Leading to Hepatic Steatosis
Sushmita Singh
Aditya Sharma
Akhilesh K. Tamrakar
Original Article 09 August 2022 Pages: 217 - 233
Silence of S1PR4 Represses the Activation of Fibroblast-like Synoviocytes by Regulating IL-17/STAT3 Signaling Pathway
Pengyu Zhang
Qiang Zhang
Zhenxia Shao
Original Article 06 September 2022 Pages: 234 - 243
Multiplex Assessment of Serum Chemokines CCL2, CCL5, CXCL1, CXCL10, and CXCL13 Following Traumatic Brain Injury
Yuwen Chen
Ying Wang
Su Liu
Original Article 15 August 2022 Pages: 244 - 255
Substance P Exacerbates the Inflammatory and Pro-osteoclastogenic Responses of Murine Osteoclasts and Osteoblasts to Staphylococcus aureus
M. Brittany Johnson
Samantha R. Suptela
Ian Marriott
Original Article 30 August 2022 Pages: 256 - 269
Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress
Wen Yang
Chunwang Jia
Lei Zhang
Original Article Open access 06 September 2022 Pages: 270 - 284
Plasma IL-36α and IL-36γ as Potential Biomarkers in Interstitial Lung Disease Associated with Rheumatoid Arthritis: a Pilot Study in the Chinese Population
Weishuai Zheng
Xingxing Hu
Zhenshun Cheng
Original Article 31 August 2022 Pages: 285 - 296
SARS-CoV-2 Variants Show a Gradual Declining Pathogenicity and Pro-Inflammatory Cytokine Stimulation, an Increasing Antigenic and Anti-Inflammatory Cytokine Induction, and Rising Structural Protein Instability: A Minimal Number Genome-Based Approach
Debmalya Barh
Sandeep Tiwari
Murtaza M. Tambuwala
Original Article 10 October 2022 Pages: 297 - 312
Diagnostic and Prognostic Value of Deregulated Circulating Long Non-coding RNA TUG1 in Elderly Patients with Severe Pneumonia
Kai Gong
Jiao Xu
Jianlei Tang
Original Article 15 September 2022 Pages: 313 - 321
The Influenza-Induced Pulmonary Inflammatory Exudate in Susceptible Tpl2-Deficient Mice Is Dictated by Type I IFN Signaling
Krishna Latha
Yesha Patel
Wendy T. Watford
Original Article 13 October 2022 Pages: 322 - 341
Mechanistic Approach for Protective Effect of ARA290, a Specific Ligand for the Erythropoietin/CD131 Heteroreceptor, against Cisplatin-Induced Nephrotoxicity, the Involvement of Apoptosis and Inflammation Pathways
Nasrin Ghassemi-Barghi
Zeynab Ehsanfar
Zahra Bayrami
Original Article 10 September 2022 Pages: 342 - 358
Transmembrane TNF-α as a Novel Biomarker for the Diagnosis of Cytokine Storms in a Mouse Model of Multiple Organ Failure
Peng Yang
Yimin Zeng
Ruping Zhang
Original Article Open access 14 September 2022 Pages: 359 - 369
MicroRNA-19a Inhibition Directly and Indirectly Ameliorates Th2 Airway Inflammation in Asthma by Targeting RUNX3
Shaojun He
Jingrun Zhou
Jiong Yang
Original Article 16 September 2022 Pages: 370 - 387
Omega-3 Effects on Ligature-Induced Periodontitis in Rats with Fructose-Induced Metabolic Syndrome
Maysa O. A. Oliveira
Álvaro R. Leonço
Maria M. Campos
Original Article 29 September 2022 Pages: 388 - 403
Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice
Zhuan Song
Ning Liu
Zhenlong Wu
Original Article 01 October 2022 Pages: 404 - 417
Pyruvate Dehydrogenase Kinase 2 Accelerates Endotoxin Shock by Promoting Mitogen-Activated Protein Kinase Activation
Chunxia Li
Jun Dai
Huabao Xiong
Original Article 29 September 2022 Pages: 418 - 431
Targeting Oxidative Stress Markers, Xanthine Oxidase, TNFRSF11A and Cathepsin L in Curcumin-Treated Collagen-Induced Arthritis: A Physiological and COSMO-RS Study
Seghira Bisset
Widad Sobhi
Yacine Benguerba
Original Article 13 October 2022 Pages: 432 - 452
Dimethyl Fumarate Attenuates Di-(2-Ethylhexyl) Phthalate-Induced Nephrotoxicity Through the Nrf2/HO-1 and NF-κB Signaling Pathways
Sorour Ashari
Navid Naghsh
Abouzar Bagheri
Original Article 05 October 2022 Pages: 453 - 467
Decreased Th1 Cells and Increased Th2 Cells in Peripheral Blood Are Associated with Idiopathic Inflammatory Myopathies Patients with Interstitial Lung Disease
Lu Cheng
Yanhong Li
Yi Liu
Original Article 20 October 2022 Pages: 468 - 479
Interleukin-33/ST2 Axis as Potential Biomarker and Therapeutic Target in Kawasaki Disease
Seigo Okada
Hiroki Yasudo
Shunji Hasegawa
Original Article 08 October 2022 Pages: 480 - 490

Volume 46, Issue 1

Neuroinflammation in Alzheimer’s Disease: Current Progress in Molecular Signaling and Therapeutics

Structure Composition and Intracellular Transport of Clathrin-Mediated Intestinal Transmembrane Tight Junction Protein

NLRP3 Inflammasome in Atherosclerosis: Putting Out the Fire of Inflammation

The Role of Macrophages and Alveolar Epithelial Cells in the Development of ARDS

Role of NLRP3 Inflammasome and Its Inhibitors as Emerging Therapeutic Drug Candidate for Alzheimer’s Disease: a Review of Mechanism of Activation, Regulation, and Inhibition

Role of T Cells in the Pathogenesis of Rheumatoid Arthritis: Focus on Immunometabolism Dysfunctions

Investigation of TLR4 Antagonists for Prevention of Intestinal Inflammation

PCSK9 Promotes Endothelial Dysfunction During Sepsis Via the TLR4/MyD88/NF-κB and NLRP3 Pathways

Hyperglycemia Aggravates Blood–Brain Barrier Disruption Following Diffuse Axonal Injury by Increasing the Levels of Inflammatory Mediators through the PPARγ/Caveolin-1/TLR4 Pathway

The Pathogenic Role of Oxidative Stress, Cytokine Expression, and Impaired Hematological Indices in Diabetic Cardiovascular Diseases

Circ_0088194 Regulates Proliferation, Migration, Apoptosis, and Inflammation by miR-30a-3p/ADAM10 Axis in Rheumatoid Arthritis Fibroblastic Synovial Cells

Morin Augmented Myocardial eNOS/cGMP/PKG Signaling Pathway and Abated Oxidative and Inflammo-apoptotic Responses in Diethyl Phthalate and Bisphenol-S Co-Exposed Male Albino Rats

Anti-inflammatory Effect of a Limonin Derivative In Vivo and Its Mechanisms in RAW264.7 Cells

Macrophage-Derived TGF-β and VEGF Promote the Progression of Trauma-Induced Heterotopic Ossification

Convergence of Fructose-Induced NLRP3 Activation with Oxidative Stress and ER Stress Leading to Hepatic Steatosis

Silence of S1PR4 Represses the Activation of Fibroblast-like Synoviocytes by Regulating IL-17/STAT3 Signaling Pathway

Multiplex Assessment of Serum Chemokines CCL2, CCL5, CXCL1, CXCL10, and CXCL13 Following Traumatic Brain Injury

Substance P Exacerbates the Inflammatory and Pro-osteoclastogenic Responses of Murine Osteoclasts and Osteoblasts to Staphylococcus aureus

Hypoxia-Inducible Factor-1α Protects Against Intervertebral Disc Degeneration Through Antagonizing Mitochondrial Oxidative Stress

Plasma IL-36α and IL-36γ as Potential Biomarkers in Interstitial Lung Disease Associated with Rheumatoid Arthritis: a Pilot Study in the Chinese Population

SARS-CoV-2 Variants Show a Gradual Declining Pathogenicity and Pro-Inflammatory Cytokine Stimulation, an Increasing Antigenic and Anti-Inflammatory Cytokine Induction, and Rising Structural Protein Instability: A Minimal Number Genome-Based Approach

Diagnostic and Prognostic Value of Deregulated Circulating Long Non-coding RNA TUG1 in Elderly Patients with Severe Pneumonia

The Influenza-Induced Pulmonary Inflammatory Exudate in Susceptible Tpl2-Deficient Mice Is Dictated by Type I IFN Signaling

Mechanistic Approach for Protective Effect of ARA290, a Specific Ligand for the Erythropoietin/CD131 Heteroreceptor, against Cisplatin-Induced Nephrotoxicity, the Involvement of Apoptosis and Inflammation Pathways

Transmembrane TNF-α as a Novel Biomarker for the Diagnosis of Cytokine Storms in a Mouse Model of Multiple Organ Failure

MicroRNA-19a Inhibition Directly and Indirectly Ameliorates Th2 Airway Inflammation in Asthma by Targeting RUNX3

Omega-3 Effects on Ligature-Induced Periodontitis in Rats with Fructose-Induced Metabolic Syndrome

Knockout of ICAT in Adipose Tissue Alleviates Fibro-inflammation in Obese Mice

Pyruvate Dehydrogenase Kinase 2 Accelerates Endotoxin Shock by Promoting Mitogen-Activated Protein Kinase Activation

Targeting Oxidative Stress Markers, Xanthine Oxidase, TNFRSF11A and Cathepsin L in Curcumin-Treated Collagen-Induced Arthritis: A Physiological and COSMO-RS Study

Dimethyl Fumarate Attenuates Di-(2-Ethylhexyl) Phthalate-Induced Nephrotoxicity Through the Nrf2/HO-1 and NF-κB Signaling Pathways

Decreased Th1 Cells and Increased Th2 Cells in Peripheral Blood Are Associated with Idiopathic Inflammatory Myopathies Patients with Interstitial Lung Disease

Interleukin-33/ST2 Axis as Potential Biomarker and Therapeutic Target in Kawasaki Disease

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