Evidence that a Novel Chalcone Derivative, Compound 27, Acts on the Epithelium Via the PI3K/AKT/Nrf2-Keap1 Signaling Pathway, to Mitigate LPS-Induced Acute Lung Injury in Mice Liqin ZhouYuting LinChaolei Chen RESEARCH 24 May 2024
TIGIT Regulates T Cell Inflammation in Airway Inflammatory Diseases Junyi KeShu HuangMinchao Duan REVIEW 23 May 2024
Aspalathin, a Primary Rooibos Flavonoid, Alleviates Mast Cell-Mediated Allergic Inflammation by the Inhibition of FcεRI Signaling Pathway Yeyoung KimSoyoung LeeSang-Hyun Kim RESEARCH 23 May 2024
PD-1 Inhibitor Aggravate Irradiation-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads Signaling Pathway via GSDMD-Mediated Pyroptosis Bibo WuShasha ZhaoShengfa Su RESEARCH 21 May 2024
Angiotensin II Type 2 Receptor Inhibits M1 Polarization and Apoptosis of Alveolar Macrophage and Protects Against Mechanical Ventilation-Induced Lung Injury Xuyang ZhengZhiguang XuLanfang Tang RESEARCH 20 May 2024
RBPJ Knockdown Promotes M2 Macrophage Polarization Through Mitochondrial ROS-mediated Notch1-Jagged1-Hes1 Signaling Pathway in Uveitis Ruyi QuYuan PengDadong Guo RESEARCH 18 May 2024
Resatorvid (TAK-242) Ameliorates Ulcerative Colitis by Modulating Macrophage Polarization and T Helper Cell Balance via TLR4/JAK2/STAT3 Signaling Pathway Xiaoling HuangRong LinFeng Gao RESEARCH 18 May 2024
4-Octyl Itaconate Attenuates Neuroinflammation in Experimental Autoimmune Encephalomyelitis Via Regulating Microglia Ning ZhaoMing YiLi Yang RESEARCH 18 May 2024
Peripheral Blood Lymphocyte Subsets and Heterogeneity of B Cell Subsets in Patients of Idiopathic Inflammatory Myositis with Different Myositis-specific Autoantibodies Zhou PanMengdi LiYusheng Zhang RESEARCH 16 May 2024
Mass Spectrometry-Based Proteomics Analysis Unveils PTPRS Inhibits Proliferation and Inflammatory Response of Keratinocytes in Psoriasis Xuyu ZhengCui ZhouKun Huang RESEARCH 13 May 2024
Silencing DDX3 Attenuates Interleukin-1β-Induced Intervertebral Disc Degeneration Through Inhibiting Pyroptosis Hongfa ZhongMingheng LiMouzhang Huang RESEARCH 13 May 2024
Oroxylin A-induced Trained Immunity Promotes LC3-associated Phagocytosis in Macrophage in Protecting Mice Against Sepsis Lijie YinZiqian BingYayi Hou RESEARCH 13 May 2024
Acacetin Attenuates Sepsis-induced Acute Lung Injury via NLRC3-NF-κB Pathway Yingchou XiaoBo ZhangYing Luo RESEARCH 13 May 2024
Regulation of Alternative Splicing of Lipid Metabolism Genes in Sepsis-Induced Liver Damage by RNA-Binding Proteins Buzukela AbuduainiZhang JiyuanSong Yunlin RESEARCH Open access 09 May 2024
Iron Overload–Dependent Ferroptosis Aggravates LPS-Induced Acute Lung Injury by Impairing Mitochondrial Function Xiaocen WangTingting WeiYuanlin Song RESEARCH 09 May 2024
Dual Regulation of Nicotine on NLRP3 Inflammasome in Macrophages with the Involvement of Lysosomal Destabilization, ROS and α7nAChR Xiaqing WuYushan TianQingyuan Hu RESEARCH 08 May 2024
Gypenoside XLIX Activates the Sirt1/Nrf2 Signaling Pathway to Inhibit NLRP3 Inflammasome Activation to Alleviate Septic Acute Lung Injury Kaixin PingRongrong YangJingquan Dong RESEARCH 08 May 2024
Esaxerenone Inhibits Interferon-γ Induced Pyroptosis of Macrophages in the Lungs of Aldosterone-treated Mice Jingyue ChangXiaomeng GaoYi Chang RESEARCH 07 May 2024
TRPV1 Regulates Proinflammatory Properties of M1 Macrophages in Periodontitis Via NRF2 Yiyang LiXiaotong GuoZhengmei Lin RESEARCH 03 May 2024
Targeted Demethylation of FOXP3-TSDR Enhances the Suppressive Capacity of STAT6-deficient Inducible T Regulatory Cells Rubén D. Arroyo-OlarteJuan C. Flores-CastelánSonia Leon-Cabrera RESEARCH Open access 03 May 2024
Retraction Note: Geniposide Attenuates LPS-Induced Injury via Up-Regulation of miR-145 in H9c2 Cells Qiang SuJunjing YaoCunjian Sheng Retraction Note 01 May 2024
The Role of Macrophage Death in Periodontitis: A Review Wen LuoChengying DuHongyan Wang REVIEW 01 May 2024
Inflammatory Protein Signatures as Predictive Disease-Specific Markers for Non-Alcoholic Steatohepatitis (NASH) Nadella MounikaSuraj Bhausaheb MungaseRamu Adela RESEARCH 27 April 2024
Integrated Single Cell Analysis Reveals An Atlas of Tumor Associated Macrophages in Hepatocellular Carcinoma Xinqiang LiRuixia LiJinzhen Cai RESEARCH 26 April 2024
STING Agonist cGAMP Attenuates Sleep Deprivation-Induced Neuroinflammation and Cognitive Deficits via TREM2 Up-Regulation Yue WangWen NiuLei Ma RESEARCH 26 April 2024
Bacillus Calmette-Guérin (BCG)-Induced Protection in Brain Disorders Khiany MathiasRichard Simon MachadoFabricia Petronilho REVIEW 26 April 2024
Sinapic Acid Mitigates Pentylenetetrazol-induced Acute Seizures By Modulating the NLRP3 Inflammasome and Regulating Calcium/calcineurin Signaling: In Vivo and In Silico Approaches Shimaa O. AliHeba R. GhaiadNoha A. Mehana RESEARCH Open access 25 April 2024
Exosomes From Human Umbilical Cord Stem Cells Suppress Macrophage-to-myofibroblast Transition, Alleviating Renal Fibrosis Qitong GuoPing LiDeying Zhang RESEARCH 25 April 2024
Exploring Pyroptosis-related Signature Genes and Potential Drugs in Ulcerative Colitis by Transcriptome Data and Animal Experimental Validation Yang ZhaoYiming MaQingsheng Liu RESEARCH 24 April 2024
Investigation of Metabolic and Inflammatory Disorder in the Aging FGF21 Knockout Mouse Lu-Qiong CaiXiu-Chun LiXiao-Ying Huang RESEARCH Open access 24 April 2024
Melatonin Attenuates Imiquimod-Induced Psoriasis-Like Inflammation and Restores the Th17/Treg Immune Balance Zhanting ShenJinqiu JiangXiaoyan Luo RESEARCH 24 April 2024
The Role of Immunocyte Infiltration Regulatory Network Based on hdWGCNA and Single-Cell Bioinformatics Analysis in Intervertebral Disc Degeneration Tuo ShaoQichang GaoZhange Yu RESEARCH 17 April 2024
ROS-Induced Gingival Fibroblast Senescence: Implications in Exacerbating Inflammatory Responses in Periodontal Disease Shuling GuoLiangliang FuHaibin Xia RESEARCH 17 April 2024
TRIM38 Induced in Respiratory Syncytial Virus-infected Cells Downregulates Type I Interferon Expression by Competing with TRIM25 to Bind RIG-I Qingqing SunXiao HanCuiqing Ma RESEARCH 17 April 2024
Mesenchymal Stem Cells Regulate Microglial Polarization via Inhibition of the HMGB1/TLR4 Signaling Pathway in Diabetic Retinopathy Jun TongGenhong YaoZhenggao Xie RESEARCH 16 April 2024
Succinic Acid Ameliorates Concanavalin A-Induced Hepatitis by Altering the Inflammatory Microenvironment and Expression of BCL-2 Family Proteins Ying CaiZhiyuan ChenYifan Lian RESEARCH 13 April 2024
CARMA3 Drives NF-κB Activation and Promotes Intervertebral Disc Degeneration: Involvement of CARMA3-BCL10-MALT1 Signalosome Yadong LiuGuiqi ZhangDongfang Yang RESEARCH 12 April 2024
The Expression of MAFB Gene in Circulating Monocytes Is Related to Chronic Inflammatory Status in T2DM Patients Wanliang ZhangWenyun ChenLing Li RESEARCH 11 April 2024
Palmatine Alleviates Particulate Matter-Induced Acute Lung Injury by Inhibiting Pyroptosis via Activating the Nrf2-Related Pathway Hao ZuoWanting ZhouChengshui Chen RESEARCH Open access 10 April 2024
RP105 Attenuates Ischemia/Reperfusion-Induced Oxidative Stress in the Myocardium via Activation of the Lyn/Syk/STAT3 Signaling Pathway Jian YangYuhong ZhaiJing Zhang RESEARCH 03 April 2024
Mast Cells are Dependent on Glucose Transporter 1 (GLUT1) and GLUT3 for IgE-mediated Activation Mirjana GrujicMd Abdul AlimGunnar Pejler RESEARCH Open access 03 April 2024
VCP Inhibition Augments NLRP3 Inflammasome Activation Ankita SharmaDhruva D. DhavaleConrad C. Weihl RESEARCH 02 April 2024
Type I/II Immune Balance Contributes to the Protective Effect of AIF-1 on Hepatic Immunopathology Induced by Schistosoma japonicum in a Transgenic Mouse Model Jiahui LeiYujie FengFei Guan RESEARCH 30 March 2024
Therapeutic Effect of Levetiracetam Against Thioacetamide-Induced Hepatic Encephalopathy Through Inhibition of Oxidative Stress and Downregulation of NF-κB, NLRP3, iNOS/NO, Pro-Inflammatory Cytokines and Apoptosis Keyvan AmirshahrokhiMahsa Imani RESEARCH 26 March 2024
The Role of H3K27me3-Mediated Th17 Differentiation in Ankylosing Spondylitis Yuening ChenWanlin LiuHongxiao Liu RESEARCH 22 March 2024
AMPK/MTOR/TP53 Signaling Pathway Regulation by Calcitonin Gene-Related Peptide Reduces Oxygen-Induced Lung Damage in Neonatal Rats through Autophagy Promotion Shaohua WangZhengzhuang ZouJian Deng RESEARCH 19 March 2024
Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells Chunnian RenQuan WangDawei He RESEARCH 18 March 2024
An Advanced Intrahepatic Cholangiocarcinoma Patient Benefits from Personalized Immunotherapy Sihui ZhuChenxi LiuBaorui Liu RESEARCH 16 March 2024
Immunomodulatory and Anti-Inflammatory Effects of Vitamin A and Tryptophan on Monocyte-Derived Dendritic Cells Stimulated with Gliadin in Celiac Disease Patients Fatemeh AsgariAbdolrahim NikzamirMohammad Rostami-Nejad RESEARCH 16 March 2024