Therapeutic efficacy of 188Re-liposome in a C26 murine colon carcinoma solid tumor model Ya-Jen ChangChin-Wei HsuTe-Wei Lee PRECLINICAL STUDIES 09 December 2012 Pages: 801 - 811
Functional and molecular characterization of kinin B1 and B2 receptors in human bladder cancer: implication of the PI3Kγ pathway V. SgnaolinT. C. B. PereiraM. M. Campos PRECLINICAL STUDIES 07 December 2012 Pages: 812 - 822
Sonic hedgehog antagonists induce cell death in acute myeloid leukemia cells with the presence of lipopolysaccharides, tumor necrosis factor-α, or interferons Frank Leigh LuChing-Chia YuJean Lu PRECLINICAL STUDIES 13 December 2012 Pages: 823 - 832
LY2801653 is an orally bioavailable multi-kinase inhibitor with potent activity against MET, MST1R, and other oncoproteins, and displays anti-tumor activities in mouse xenograft models S. Betty YanVictoria L. PeekRichard A. Walgren PRECLINICAL STUDIES Open access 29 December 2012 Pages: 833 - 844
Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancer Peter M. WilsonMelissa J. LaBonteRobert D. Ladner PRECLINICAL STUDIES 09 January 2013 Pages: 845 - 857
Tetra-O-methyl nordihydroguaiaretic acid, an inhibitor of Sp1-mediated survivin transcription, induces apoptosis and acts synergistically with chemo-radiotherapy in glioblastoma cells Angel Mauricio Castro-GameroKleiton Silva BorgesLuiz Gonzaga Tone PRECLINICAL STUDIES 09 January 2013 Pages: 858 - 870
Preclinical antitumor activity of a nanoparticulate SN38 Mazin F. Al-kasspoolesStephen K. WilliamsonKatherine F. Roby PRECLINICAL STUDIES 09 January 2013 Pages: 871 - 880
Monitoring the effects of bevacizumab beyond progression in a murine colorectal cancer model: a functional imaging approach L. HeijmenC. J. A. PuntH. W. M. van Laarhoven PRECLINICAL STUDIES 17 January 2013 Pages: 881 - 890
Phase Ib trial of the oral angiogenesis inhibitor pazopanib administered concurrently with erlotinib Grace K. DyJeffrey R. InfanteHoward A. Burris III PHASE I STUDIES 08 November 2012 Pages: 891 - 899
A phase I, open-label, single-arm study for QT assessment of eribulin mesylate in patients with advanced solid tumors Thierry LesimpleJulien EdelineLarisa Reyderman PHASE I STUDIES 11 November 2012 Pages: 900 - 909
A phase I study of intravenous aflibercept with FOLFIRI in Japanese patients with previously treated metastatic colorectal cancer Takayuki YoshinoKentaro YamazakiAtsushi Ohtsu PHASE I STUDIES Open access 20 November 2012 Pages: 910 - 917
A phase 1 study of gemcitabine combined with dasatinib in patients with advanced solid tumors David S. HongJennifer Hsing ChoeRazelle Kurzrock PHASE I STUDIES 20 November 2012 Pages: 918 - 926
Phase Ib trial of the oral angiogenesis inhibitor pazopanib administered concurrently with pemetrexed in patients with advanced solid tumors Jeffrey R. InfanteSilvia NovelloAlex A. Adjei PHASE I STUDIES 22 November 2012 Pages: 927 - 936
Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma Andrew PoklepovicLeena YouseffianJohn D. Roberts PHASE I STUDIES 13 January 2013 Pages: 937 - 942
A phase I study of sorafenib, oxaliplatin and 2 days of high dose capecitabine in advanced pancreatic and biliary tract cancer: a Wisconsin oncology network study Noelle K. LoConteKyle D. HolenSam J. Lubner PHASE I STUDIES 21 December 2012 Pages: 943 - 948
Evaluation of the pharmacodynamics and pharmacokinetics of the PARP inhibitor olaparib: a Phase I multicentre trial in patients scheduled for elective breast cancer surgery Nigel BundredJanis GardovskisJ. Michael Dixon PHASE I STUDIES 13 January 2013 Pages: 949 - 958
Phase I study of oral CP-4126, a gemcitabine derivative, in patients with advanced solid tumors F. E. StuurmanE. E. VoestA. Hendlisz PHASE I STUDIES 24 January 2013 Pages: 959 - 966
A phase I trial of KX2-391, a novel non-ATP competitive substrate-pocket- directed SRC inhibitor, in patients with advanced malignancies Aung NaingRoger CohenAlex A. Adjei PHASE I STUDIES 30 January 2013 Pages: 967 - 973
A phase I dose-escalation study of intravenous panobinostat in patients with lymphoma and solid tumors Sunil SharmaJoachim BeckH. Miles Prince PHASE I STUDIES 02 February 2013 Pages: 974 - 985
First-in-human phase 1/2a trial of CRLX101, a cyclodextrin-containing polymer-camptothecin nanopharmaceutical in patients with advanced solid tumor malignancies Glen J. WeissJoseph ChaoYun Yen PHASE II STUDIES 09 February 2013 Pages: 986 - 1000
Phase II study to assess the efficacy, safety and tolerability of the mitotic spindle kinesin inhibitor AZD4877 in patients with recurrent advanced urothelial cancer Robert JonesJacqueline VukyGary Hudes PHASE II STUDIES 18 January 2013 Pages: 1001 - 1007
A phase II study of cediranib (AZD 2171) in treatment naive patients with progressive unresectable recurrent or metastatic renal cell carcinoma. A trial of the PMH phase 2 consortium Srikala S. SridharMary J. MackenzieMalcolm J. Moore PHASE II STUDIES 26 January 2013 Pages: 1008 - 1015
A phase 2 multicenter study of tivantinib (ARQ 197) monotherapy in patients with relapsed or refractory germ cell tumors Darren R. FeldmanLawrence H. EinhornRobert J. Motzer PHASE II STUDIES 17 February 2013 Pages: 1016 - 1022
Safety and pharmacokinetics of the antisense oligonucleotide (ASO) LY2181308 as a single-agent or in combination with idarubicin and cytarabine in patients with refractory or relapsed acute myeloid leukemia (AML) Harry P. ErbaHamid SayarMichael Andreeff PHASE II STUDIES 10 February 2013 Pages: 1023 - 1034
Maintenance single-agent bevacizumab or observation after first-line chemotherapy in patients with metastatic colorectal cancer: a multicenter retrospective study Luca MoscettiFabrizio NelliEnzo M. Ruggeri PHASE II STUDIES 17 February 2013 Pages: 1035 - 1043
A randomized, double-blind, placebo-controlled, Phase II study with and without enzastaurin in combination with docetaxel-based chemotherapy in patients with castration-resistant metastatic prostate cancer Robert DreicerJorge GarciaDerek Raghavan PHASE II STUDIES 24 February 2013 Pages: 1044 - 1050
Potential factors correlating to the PMDA’s decision to waive Japanese Phase 2 and 3 studies for oncology drugs New Drug Application in Japan Keitaro NakajimaKoji ChibaToshio Suwa PHASE III STUDIES 19 December 2012 Pages: 1051 - 1055
Effect of selection of QTc formula on eligibility of cancer patients for phase I clinical trials Mitesh J. BoradArundhati D. SomanDaniel D. Von Hoff SHORT REPORT 16 December 2012 Pages: 1056 - 1065
Opioid growth factor (OGF) for hepatoblastoma: a novel non-toxic treatment Moshe RogosnitzkyMilton J. FinegoldIan S. Zagon SHORT REPORT 30 December 2012 Pages: 1066 - 1070
Ipilimumab associated hepatitis: imaging and clinicopathologic findings Kyung Won KimNikhil H. RamaiyaNageatte Ibrahim SHORT REPORT 14 February 2013 Pages: 1071 - 1077
Risk of hand-foot skin reaction with the novel multikinase inhibitor regorafenib: a meta-analysis Viswanath Reddy BelumShenhong WuMario E. Lacouture REVIEW 23 May 2013 Pages: 1078 - 1086
Cardiac glycosides in cancer therapy: from preclinical investigations towards clinical trials M. SlingerlandC. CerellaH. Gelderblom REVIEW 10 June 2013 Pages: 1087 - 1094
Erratum to: Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma Andrew PoklepovicLeena E. YoussefianJohn D. Roberts Erratum 06 July 2013 Pages: 1095 - 1095