Maximisation of perfusion systems and process comparison with batch-type cultures J. B. GriffithsD. LoobyA. J. Racher OriginalPaper Pages: 3 - 9
An engineering analysis of rotating sieves for hybridoma cell retention ins stirred tank bioreactors Eric FavreThomas Thaler OriginalPaper Pages: 11 - 19
Avoiding rapid growth at high cell densities: A potentially important optimisation criterion for hybridoma cultures L. K. NielsenW. NiloperbowoP. F. Greenfield OriginalPaper Pages: 21 - 27
Design and performance of a trickle-bed bioreactor with immobilized hybridoma cells H. A. PhillipsJ. M. ScharerM. Moo-Young OriginalPaper Pages: 29 - 40
Modified CelliGen-packed bed bioreactors for hybridoma cell cultures Guozheng WangWenying ZhangAvinoam Kadouri OriginalPaper Pages: 41 - 49
The membrane dialysis bioreactor with integrated radial-flow fixed bed —a new approach for continuous cultivation of animal cells Armin BohmannRalf PörtnerHerbert Märkl OriginalPaper Pages: 51 - 57
Optimal medium use for continuous high density perfusion processes Heino BüntemeyerClaus WalleriusJürgen Lehmann OriginalPaper Pages: 59 - 67
Novel cell lines derived from transgenic mice expressing recombinant human proteins Frédéric PerraudWilfried DalemansAndrea Pavirani OriginalPaper Pages: 69 - 75
Expression of human α1 antitrypsin in transgenic sheep A. CarverG. WrightI. Garner OriginalPaper Pages: 77 - 84
Specific monoclonal antibody productivity and the cell cycle-comparisons of batch, continuous and perfusion cultures Mohamed Al-RubeaiA. N. EmeryD. C. Jan OriginalPaper Pages: 85 - 97
The role of laminin in attachment, growth, and differentiation of cultured cells: a brief review Mats Paulsson ReviewPaper Pages: 99 - 106
Differentiation of myoblasts and CNS cells grown either separately or as co-cultures on microcarriers A. ShaharS. ReuvenyA. Shainberg OriginalPaper Pages: 107 - 115
Fragmented DNA and apoptotic bodies document the programmed way of cell death in hybridoma cultures František FraněkTomáš VomastekJana Dolníková OriginalPaper Pages: 117 - 123
Physiology of myeloma cells grown in glucose-limited chemostat cultures P. R. LeveringJ. A. M. van HeijstC. M. G. Sünnen OriginalPaper Pages: 125 - 130
Enhancing monoclonal antibodies and hybridoma cell lines Sally S. Seaver OriginalPaper Pages: 131 - 139
Recombinant protein production in insect cell cultures infected with a temperature-sensitive baculovirus Jianyong WuGlenn A. KingMattheus F. A. Goosen OriginalPaper Pages: 141 - 147
Modelling the growth and protein production by insect cells following infection by a recombinant baculovirus in suspension culture J. PowerP. F. GreenfieldS. Reid OriginalPaper Pages: 149 - 155
Expression of plasminogen activator and plasminogen activator inhibitor mRNA in human fibroblasts grown on different substrates James VaraniRobert G. SitrinWilliam Hillegas OriginalPaper Pages: 157 - 162
The organotypic culture of human skin keratinocytes and fibroblasts to achieve form and function Nancy L. ParenteauPatrick BilboMireille Rosenberg OriginalPaper Pages: 163 - 171
Evaluation of a microcarrier process for large-scale cultivation of attenuated hepatitis A B. H. JunkerF. WuB. C. Buckland OriginalPaper Pages: 173 - 187
Experimental approaches to guarantee minimal risk of potential virus in purified monoclonal antibodies W. BertholdJ. WalterW. Werz OriginalPaper Pages: 189 - 201
Regulatory considerations when developing biological products Robert W. KozakCharles N. DurforCurtis L. Scribner OriginalPaper Pages: 203 - 210
DNA fingerprinting—a valuable new technique for the characterisation of cell lines Glyn StaceyBryan BoltonBryan Griffiths OriginalPaper Pages: 211 - 216
Monitoring hybridoma metabolism in continuous suspension culture at the intracellular level Georg SchmidThoralf Keller OriginalPaper Pages: 217 - 229
Process development for the production of recombinant antibodies using the glutamine synthetase (GS) system M. E. BrownG. RennerT. Hassell OriginalPaper Pages: 231 - 236
Effect of amplification ofdhfr andlac Z genes on growth and β-galactosidase expression in suspension cultures of recombinant CHO cells Man Bock GuJeffrey A. KernDhinakar S. Kompala OriginalPaper Pages: 237 - 245
Flow cytometry and two-dimensional electrophoresis (2-DE) for system evaluation of long term continuous perfused animal cell cultures in macroporous beads M. ReiterN. BorthH. Katinger OriginalPaper Pages: 247 - 253
