1. Mass culture of mammalian cells as a national project

   • Isao Yamane

   BriefCommunication Pages: 1 - 2

2. Japanese animal cell biotechnology opens to the world

   • Hiroki Murakami

   BriefCommunication Pages: 3 - 4

3. Introduction

   • Hideo Sakamoto

   EditorialNotes Pages: 5 - 7

4. Establishment of vascular endothelial cell lines in a serum-free culture and the discovery of endothelin and a Vasoactive Intestinal Contractor (VIC)

   • Youji Mitsui
   • Kaname Saida
   • Mieko Kobayashi

   OriginalPaper Pages: 9 - 16

5. Optimization of cell culture conditions for production of biologically active proteins

   • Shinji Hosoi
   • Hiromasa Miyaji
   • Seiji Sato

   OriginalPaper Pages: 17 - 34

6. Development of a serum-free and heat-sterilizable medium and continuous high-density cell culture

   • Yoshiki Minamoto
   • Koji Ogawa
   • Koji Mitsugi

   OriginalPaper Pages: 35 - 51

7. Effective production of anti-tetanus toxoid and anti-HBsAg human monoclonal antibodies by serum-free culture of hybridomas

   • Kazuaki Kitano
   • Yuzo Ichimori
   • Kyozo Tsukamoto

   OriginalPaper Pages: 53 - 74

8. “Differentiation Induction” culture of human leukemic myeloid cells stimulates high production of macrophage differentiation inducing factor

   • Tsutomu Abe
   • Mitsuharu Ohno
   • Ryoji Kodaira

   OriginalPaper Pages: 75 - 93

9. Serum-free cultivation of anchorage-dependent cells on microcarrier: Effective production of human macrophage colony-stimulating factor

   • Sakae Satoh
   • Junji Kobayashi
   • Masaru Otani

   OriginalPaper Pages: 95 - 114