Applications of cell culture for the improvement of human health Barry C. Buckland Introduction Pages: 1 - 2
Cultural and physiological factors affecting expression of recombinant proteins J. B. GriffithsA. J. Racher OriginalPaper Pages: 3 - 9
Selecting and designing cell lines for improved physiological characteristics J. R. BirchR. C. BorastonR. P. Field OriginalPaper Pages: 11 - 16
Applications of improved stoichiometric model in medium design and fed-batch cultivation of animal cells in bioreactor Liangzhi XieDaniel I. C. Wang OriginalPaper Pages: 17 - 29
Diverse effects of essential (n−6 andn−3) fatty acids on cultured cells Stephanos I. GrammatikosPapasani V. SubbaiahWilliam M. Miller OriginalPaper Pages: 31 - 50
Enhancement effects of BSA and linoleic acid on hybridoma cell growth and antibody production Masaki KobayashiSatoru KatoKen-ichi Suga OriginalPaper Pages: 51 - 56
Growth rate suppression of cultured mammalian cells enhances protein productivity Kazunari TakahashiSatoshi TeredaEiji Suzuki OriginalPaper Pages: 57 - 64
Growth and interferon-γ production in batch culture of CHO cells V. LeelavatcharamasA. N. EmeryM. Al-Rubeai OriginalPaper Pages: 65 - 71
Metabolic and kinetic studies of hybridomas in exponentially fed-batch cultures using T-flasks Ana E. HigaredaLourival D. PossaniOctavio T. Ramírez OriginalPaper Pages: 73 - 86
Adaptation of mammalian cells to non-ammoniagenic media Michael ButlerAndrew Christie OriginalPaper Pages: 87 - 94
Effect of endogenous proteins on growth and antibody productivity in hybridoma batch cultures Patrick J. FarrellNicolas KalogerakisLeo A. Behie OriginalPaper Pages: 95 - 102
Extracellular insulin degrading activity creates instability in a CHO-based batch-refeed continuous process Denis DrapeauYen-Tung LuanS. Robert Adamson OriginalPaper Pages: 103 - 109
Low temperature cultivation — A step towards process optimisation Ralf WeidemannAndreas LudwigGerlinde Kretzmer OriginalPaper Pages: 111 - 116
Induction of apoptosis in oxygen-deprived cultures of hybridoma cells Sylvain MercilleBernard Massie OriginalPaper Pages: 117 - 128
Maximization of recombinant protein yield in the insect cell/baculovirus system by one-time addition of nutrients to high-density batch cultures C. BédardA. KamenB. Massie OriginalPaper Pages: 129 - 138
Recombinant protein expression in aDrosophila cell line: comparison with the baculovirus system A. R. BernardT. A. KostA. Mills OriginalPaper Pages: 139 - 144
Scale-up of the adenovirus expression system for the production of recombinant protein in human 293S cells Alain GarnierJohanne CôtéBernard Massie OriginalPaper Pages: 145 - 155
Relationship between oxygen uptake rate and time of infection of Sf9 insect cells infected with a recombinant baculovirus T. K. Kathy WongLars K. NielsenSteven Reid OriginalPaper Pages: 157 - 167
Optimization of vaccine production for animal health W. NoeR. BuxW. Werz OriginalPaper Pages: 169 - 176
Evaluation of monitoring approaches and effects of culture conditions on recombinant protein production in baculovirus-infected insect cells William T. HenslerSpiros N. Agathos OriginalPaper Pages: 177 - 186
The analysis of protein pharmaceuticals: Near future advances C. Russell Middaugh OriginalPaper Pages: 187 - 194
The effect of protein synthesis inhibitors on the glycosylation site occupancy of recombinant human prolactin Marc ShelikoffA. J. SinskeyGregory Stephanopoulos OriginalPaper Pages: 195 - 208
Effect of lipid supplements on the production and glycosylation of recombinant interferon-γ expressed in CHO cells Nigel JenkinsPaula CastroAlan Bull OriginalPaper Pages: 209 - 215
Role of environmental conditions on the expression levels, glycoform pattern and levels of sialyltransferase for hFSH produced by recombinant CHO cells W. ChotigeatY. WatanapokasinP. P. Gray OriginalPaper Pages: 217 - 221
Glycosylation and functional activity of anti-D secreted by two human lymphoblastoid cell lines Diane CantJohn BarfordAndrew Gooley OriginalPaper Pages: 223 - 228
Interaction of cell culture with downstream purification: a case study Wolf BertholdRalph Kempken OriginalPaper Pages: 229 - 242
Evaluation of membranes for use in on-line cell separation during mammalian cell perfusion processes Heino BüntemeyerChristoph BöhmeJürgen Lehmann OriginalPaper Pages: 243 - 251
Vortex flow filtration of mammalian and insect cells Steven J. HawrylikDavid J. WasilkoS. Edward Lee OriginalPaper Pages: 253 - 258
Automated imunoanalysis systems for monitoring mammalian cell cultivation processes Birgitt SchulzeCornelia MiddendorfMichael Howaldt OriginalPaper Pages: 259 - 269
A direct computer control concept for mammalian cell fermentation processes Heino BüntemeyerRainer MarzahlJürgen Lehmann OriginalPaper Pages: 271 - 279
Automated monitoring of cell concentration and viability using an image analysis system Fumio MaruhashiSei MurakamiKenji Baba OriginalPaper Pages: 281 - 289
Software sensors for the monitoring of perfusion cultures: Evaluation of the hybridoma density and the medium composition from glucose concentration measurements François PelletierChristian FonteixJean-Marc Engasser OriginalPaper Pages: 291 - 299
Design of a bubble-swawm bioreactor for animal cell culture F. GudermannD. LütkemeyerJ. Lehmann OriginalPaper Pages: 301 - 309
Quantitative investigations of cell-bubble interactions using a foam fractionation technique W. S. TanY. L. Chen OriginalPaper Pages: 321 - 328
Prediction of mechanical damage to animal cells in turbulence C. R. ThomasM. Al-RubeaiZ. Zhang OriginalPaper Pages: 329 - 335
Repeated-batch cultures of Baby Hamster Kidney cell aggregates in stirred vessels J. L. MoreiraA. S. FelicianoM. J. T. Carrondo OriginalPaper Pages: 337 - 349
Towards the development of a bioartificial pancreas: Immunoisolation and NMR monitoring of mouse insulinomas A. SambanisK. K. PapasI. Constantinidis OriginalPaper Pages: 351 - 363
Overview of a quality assurance/quality control compliance program consistent with FDA regulations and policies for somatic cell and gene therapies: a four year experience Gary C. du MoulinZorina PitkinDylan Hamilton OriginalPaper Pages: 365 - 372