1. Preface

   • Michel M. Ouellette

   OriginalPaper Pages: 1 - 2

2. Function, replication and structure of the mammalian telomere

   • Dominique Broccoli

   OriginalPaper Pages: 3 - 12

3. Telomerase dysfunction and dyskeratosis congenita

   • Amanda J. Walne
   • Inderjeet Dokal

   OriginalPaper Pages: 13 - 22

4. Regulation of hTERT transcription: a target of cellular and viral mechanisms for immortalization and carcinogenesis

   • Izumi Horikawa
   • Eriko Michishita
   • J. Carl Barrett

   OriginalPaper Pages: 23 - 32

5. Use of exogenous hTERT to immortalize primary human cells

   • Kwang M. Lee
   • Kyung H. Choi
   • Michel M. Ouellette

   OriginalPaper Pages: 33 - 38

6. The use of hTERT-immortalized cells in tissue engineering

   • Moustapha Kassem
   • Basem M. Abdallah
   • Jorge S. Burns

   OriginalPaper Pages: 39 - 46

7. Immortalized cells as experimental models to study cancer

   • Jesse S. Boehm
   • William C. Hahn

   OriginalPaper Pages: 47 - 59

8. Telomerase detection in the diagnosis and prognosis of cancer

   • Eiso Hiyama
   • Keiko Hiyama

   OriginalPaper Pages: 61 - 74

9. Targeting human telomerase for cancer therapeutics

   • Lionel Guittat
   • Patrizia Alberti
   • Jean-Louis Mergny

   Review Pages: 75 - 90

10. Telomerase as a tumor-associated antigen for cancer immunotherapy

    • Kunal P. Patel
    • Robert H. Vonderheide

    Review Pages: 91 - 99