1. Introduction. From target to market A report of the 17th ESACT Meeting Tylösand, Sweden, June 10–14, 2001

   • Elke Lüllau
   • Elisabeth Lindner-Olsson

   Editorial Introduction Pages: 1 - 1

2. Chemical genomics: massively parallel technologies for rapid lead identification and target validation

   • Uli Hacksell
   • Norman Nash
   • Mark R. Brann

   OriginalPaper Pages: 3 - 10

3. Over-expression of protein kinase Bα enhances recombinant protein expression in transient systems

   • Elham Ettehadieh
   • Sharon Wong-Madden
   • Arvia E. Morris

   OriginalPaper Pages: 11 - 14

4. 100-liter transient transfection

   • Philippe Girard
   • Madiha Derouazi
   • Florian M. Wurm

   OriginalPaper Pages: 15 - 21

5. Increased production of a secreted glycoprotein in engineered CHO cells through amplification of a transcription factor

   • Venkata R. M. Mangalampalli
   • Mark C. Mowry
   • Dhinakar S. Kompala

   OriginalPaper Pages: 23 - 35

6. Rapid expression of recombinant proteins in modified CHO cells using the baculovirus system

   • Luciano Ramos
   • Lisa A. Kopec
   • James F. Kane

   OriginalPaper Pages: 37 - 41

7. The use of UCOE vectors in combination with a preadapted serum free, suspension cell line allows for rapid production of large quantities of protein

   • Trish Benton
   • Tim Chen
   • Christopher Bebbington

   OriginalPaper Pages: 43 - 46

8. Serum-free production of a chimeric E-selectin-IgG protein from 1 to 100 l scale: Repeated batch cultivation versus continuous spin filter perfusion

   • Andreas Werner
   • Dirk Lütkemeyer
   • Johannes Müthing

   OriginalPaper Pages: 47 - 56

9. S-phase synchronized CHO cells show elevated transfection efficiency and expression using CaPi

   • Frédéric Grosjean
   • Pascal Batard
   • Florian M. Wurm

   OriginalPaper Pages: 57 - 62

10. The roles of a process development group in biopharmaceutical process startup

    • Charles F. Goochee

    OriginalPaper Pages: 63 - 76

11. Optimisation of protein expression and establishment of the Wave Bioreactor for Baculovirus/insect cell culture

    • Wilfried Weber
    • Eric Weber
    • Klaus Memmert

    OriginalPaper Pages: 77 - 85

12. Rapid titration of adenoviral infectivity by flow cytometry in batch culture of infected HEK293 cells

    • Vincent Gueret
    • Juan A. Negrete-Virgen
    • Mohamed Al-Rubeai

    OriginalPaper Pages: 87 - 97

13. A new seed-train expansion method for recombinant mammalian cell lines

    • Rüdiger Heidemann
    • Mokhtar Mered
    • Konstantin Konstantinov

    OriginalPaper Pages: 99 - 108

14. Process development for functional membrane receptor production in mammalian cells

    • Christel Fenge
    • Irma Jansson
    • Michael Wood

    OriginalPaper Pages: 109 - 117

15. New technologies for automated cell counting based on optical image analysis `The Cellscreen'

    • Marlies Brinkmann
    • Dirk Lütkemeyer
    • Jürgen Lehmann

    OriginalPaper Pages: 119 - 127

16. In-situ microscopy: Online process monitoring of mammalian cell cultures

    • Klaus Joeris
    • Jan-Gerd Frerichs
    • Thomas Scheper

    OriginalPaper Pages: 129 - 134

17. Bioprocess development for the cultivation of human T-lymphocytes in a clinical scale

    • H. Bohnenkamp
    • U. Hilbert
    • T. Noll

    OriginalPaper Pages: 135 - 145

18. Real-time RT-PCR detection of retroviral contaminations of cells and cell lines

    • Katja Müller
    • Manfred Wirth

    OriginalPaper Pages: 147 - 153

19. Induction of a T helper cell response against the tumor-associated antigen HER2 using monocyte-derived dendritic cells

    • J. Metzger
    • N. Nicklisch
    • H. Bernhard

    OriginalPaper Pages: 155 - 164

20. Announcement.18th ESACT MEETING May 11–15, 2003Granada, Spain

    Announcement Pages: 165 - 165