Hirudin ameliorates diabetic nephropathy by inhibiting Gsdmd-mediated pyroptosis Jiarui HanZhenkui ZuoXinxin Pang Original Article 02 July 2021 Pages: 573 - 589
MiR-199a-5p-containing macrophage-derived extracellular vesicles inhibit SMARCA4 and alleviate atherosclerosis by reducing endothelial cell pyroptosis Weijie LiangJun ChenQiang Jie Original Article 05 August 2022 Pages: 591 - 605
TRIM64 promotes ox-LDL-induced foam cell formation, pyroptosis, and inflammation in THP-1-derived macrophages by activating a feedback loop with NF-κB via IκBα ubiquitination Chao ZhuWei ChenXiaoliang Cong Original Article Open access 14 October 2022 Pages: 607 - 620
Syringaresinol protects against diabetic nephropathy by inhibiting pyroptosis via NRF2-mediated antioxidant pathway Guangru LiChang LiuLiang Yang RESEARCH 14 January 2023 Pages: 621 - 639
Diesel exhaust exposure alters the expression of networks implicated in neurodegeneration in zebrafish brains M. Saeid JamiHiromi MurataJeff M. Bronstein Original Article Open access 31 May 2021 Pages: 641 - 655
Prenatal dexamethasone exposure induces anxiety- and depressive-like behavior of male offspring rats through intrauterine programming of the activation of NRG1-ErbB4 signaling in hippocampal PV interneurons Shuai ZhangShuwei HuDan Xu Original Article 29 June 2021 Pages: 657 - 678
CaMKII and CaV3.2 T-type calcium channel mediate Connexin-43-dependent inflammation by activating astrocytes in vincristine-induced neuropathic pain Gui-zhou LiYa-hui HuYun-man Li Original Article 20 July 2021 Pages: 679 - 702
microRNA-149-5p mediates the PM2.5-induced inflammatory response by targeting TAB2 via MAPK and NF-κB signaling pathways in vivo and in vitro Qiuyue LiSiling LiLin Tian Original Article 31 July 2021 Pages: 703 - 717
FK506-binding protein 2 (FKBP13) inhibit Bax-induced apoptosis in Saccharomyces cerevisiae (yeast) Damilare D. AkintadeBhabatosh Chaudhuri Original Article Open access 03 August 2021 Pages: 719 - 728
Induction of Sestrin2 by pterostilbene suppresses ethanol-triggered hepatocyte senescence by degrading CCN1 via p62-dependent selective autophagy Yiming JiangYing ZhouChunfeng Lu Original Article 17 August 2021 Pages: 729 - 749
Neuroprotective properties of queen bee acid by autophagy induction Guadalupe Martínez-ChacónMarta Paredes-BarqueroMireia Niso-Santano Original Article Open access 27 August 2021 Pages: 751 - 770
Integrated lipidomic and transcriptomic analysis reveals clarithromycin-induced alteration of glycerophospholipid metabolism in the cerebral cortex of mice Xiaojie WangLiang WangXiaobo Cen Original Article 30 August 2021 Pages: 771 - 793
Exploring the ATR-CHK1 pathway in the response of doxorubicin-induced DNA damages in acute lymphoblastic leukemia cells Andrea Ghelli Luserna Di RoràMartina GhettiGiorgia Simonetti Original Article Open access 14 September 2021 Pages: 795 - 811
ERRα contributes to HDAC6-induced chemoresistance of osteosarcoma cells Qing HeChangzhi YuYantao Chen Original Article 15 September 2021 Pages: 813 - 825
Ferroptosis: From regulation of lipid peroxidation to the treatment of diseases Yonghui LvMeiying WuJunqing Wang Review 02 December 2022 Pages: 827 - 851
Potential functions and therapeutic implications of glioma-resident mesenchymal stem cells Qing ZhangJialin WangFusheng Liu Review 03 May 2023 Pages: 853 - 866
MiR-17-5p/FOXL2/CDKN1B signal programming in oocytes mediates transgenerational inheritance of diminished ovarian reserve in female offspring rats induced by prenatal dexamethasone exposure Xiaohan GongShiyun DaiDan Xu Original Article 19 September 2021 Pages: 867 - 883
Vitamin D3/VDR inhibits inflammation through NF-κB pathway accompanied by resisting apoptosis and inducing autophagy in abalone Haliotis discus hannai Dong HuangYanlin GuoKangsen Mai Original Article 12 October 2021 Pages: 885 - 906
Shikonin inhibits neuronal apoptosis via regulating endoplasmic reticulum stress in the rat model of double-level chronic cervical cord compression Min YaoGan LiXue-jun Cui Original Article 14 January 2022 Pages: 907 - 928
CircRNA_0026344 via miR-21 is involved in cigarette smoke–induced autophagy and apoptosis of alveolar epithelial cells in emphysema Jing ZhaoHaibo XiaQizhan Liu Original Article 15 September 2021 Pages: 929 - 944
Cadmium affects autophagy in the human intestinal cells Caco-2 through ROS-mediated ERK activation Myriam MireaultYong XiaoCatherine Jumarie Original Article Open access 28 September 2021 Pages: 945 - 966
Prognostic significance of NT5E/CD73 in neuroblastoma and its function in CSC stemness maintenance Drishti JainDinesh Babu SomasundaramNatarajan Aravindan Original Article 13 November 2021 Pages: 967 - 989
Development, scrutiny, and modulation of transient reporter gene assays of the xenobiotic metabolism pathway in zebrafish hepatocytes Sebastian Lungu-MiteaYuxin HanJohan Lundqvist Original Article Open access 15 October 2021 Pages: 991 - 1013
METTL14 promotes doxorubicin-induced cardiomyocyte ferroptosis by regulating the KCNQ1OT1-miR-7-5p-TFRC axis Shaowei ZhuangYan MaShengyang Jiang Original Article 14 October 2021 Pages: 1015 - 1035
Suspension state and shear stress enhance breast tumor cells EMT through YAP by microRNA-29b Boyuan ZhaoYonggang Lv Original Article 07 October 2021 Pages: 1037 - 1052
MMP-9 reinforces radiation-induced delayed invasion and metastasis of neuroblastoma cells through second-signaling positive feedback with NFκB via both ERK and IKK activation Dinesh Babu SomasundaramSheeja AravindanNatarajan Aravindan Original Article 09 October 2021 Pages: 1053 - 1076
Uterine deficiency of Dnmt3b impairs decidualization and causes consequent embryo implantation defects Jing LongWeike LiRufei Gao Original Article 13 November 2021 Pages: 1077 - 1098
MiR-337-3p confers protective effect on facet joint osteoarthritis by targeting SKP2 to inhibit DUSP1 ubiquitination and inactivate MAPK pathway Shengsheng JianDixin LuoXiaozhong Zhou Original Article 25 October 2021 Pages: 1099 - 1118
Serotonin type-3 receptor antagonists selectively kill melanoma cells through classical apoptosis, microtubule depolymerisation, ERK activation, and NF-κB downregulation Anita Barzegar-fallahHouman AlimoradiSarah K. Baird Original Article 15 October 2021 Pages: 1119 - 1135
The H3K27 demethylase controls the lateral line embryogenesis of zebrafish Dongmei TangYitong LuYingzi He Original Article Open access 29 October 2021 Pages: 1137 - 1152
YEATS2 regulates the activation of TAK1/NF-κB pathway and is critical for pancreatic ductal adenocarcinoma cell survival Hao ShengFang ZhengFeng Zhang Original Article 23 October 2021 Pages: 1 - 16
A deficient MIF-CD74 signaling pathway may play an important role in immunotherapy-induced hyper-progressive disease Jiahui WangJinsheng HongDuojiao Wu Original Article 19 November 2021 Pages: 1169 - 1180