Articles

1. Elongin B promotes breast cancer progression by ubiquitinating tumor suppressor p14/ARF

   • Xin-Yi Sui
   • Xiao-Yan Ma
   • Wen-Juan Zhang

   RESEARCH Open access 23 April 2024 Article: 24

   

2. Activation of CTU2 expression by LXR promotes the development of hepatocellular carcinoma

   • Chao Xue
   • Zhuo Wei
   • Yajun Duan

   RESEARCH Open access 17 April 2024 Article: 23

   

3. circRNA-PTPN4 mediated regulation of FOXO3 and ZO-1 expression: implications for blood–brain barrier integrity and cognitive function in uremic encephalopathy

   • Yuhan Liu
   • Yanling Qin
   • Yanning Zhang

   RESEARCH Open access 17 April 2024 Article: 22

   

4. The transcriptomic signature of respiratory sensitizers using an alveolar model

   • Matthew Gibb
   • James Y. Liu
   • Christie M. Sayes

   RESEARCH Open access 08 April 2024 Article: 21

   

5. Administration of Gas6 attenuates lung fibrosis via inhibition of the epithelial-mesenchymal transition and fibroblast activation

   • Ye-Ji Lee
   • Minsuk Kim
   • Jihee Lee Kang

   RESEARCH Open access 05 April 2024 Article: 20

   

6. YTHDC1 promotes the malignant progression of gastric cancer by promoting ROD1 translocation to the nucleus

   • Danhong Dong
   • Jiangpeng Wei
   • Xisheng Yang

   Research Open access 04 April 2024 Article: 19

   

7. Establishment and characterization of cytochrome P450 1A1 CRISPR/Cas9 Knockout Bovine Foetal Hepatocyte Cell Line (BFH12)

   • Silvia Iori
   • Caterina D’Onofrio
   • Mery Giantin

   RESEARCH Open access 26 March 2024 Article: 18

   

8. Ferroptosis mechanisms and regulations in cardiovascular diseases in the past, present, and future

   • Wenxi Fang
   • Saiyang Xie
   • Wei Deng

   REVIEW Open access 21 March 2024 Article: 17

   

9. The mitochondrial UPR induced by ATF5 attenuates intervertebral disc degeneration via cooperating with mitophagy

   • Wen-Ning Xu
   • Huo-Liang Zheng
   • Li-Xin Zhu

   RESEARCH Open access 13 March 2024 Article: 16

   

10. Fetal growth restriction exhibits various mTOR signaling in different regions of mouse placentas with altered lipid metabolism

    • Jie Dong
    • Qian Xu
    • Xiaohong Wang

    RESEARCH Open access 07 March 2024 Article: 15

    

11. RNF115 aggravates tumor progression through regulation of CDK10 degradation in thyroid carcinoma

    • Jinxiang Zhu
    • Longwei Guo
    • Chongwen Xu

    RESEARCH Open access 20 February 2024 Article: 14

    

12. Nupr1-mediated vascular smooth muscle cell phenotype transformation involved in methamphetamine induces pulmonary hypertension

    • Jie Zhou
    • Dan Guo
    • Wei-Bing Xie

    RESEARCH Open access 13 February 2024 Article: 13

    

13. Repositioning baloxavir marboxil as VISTA agonist that ameliorates experimental asthma

    • Jian-wen Di
    • Yi-xin Wang
    • Jun Liu

    RESEARCH Open access 10 February 2024 Article: 12

    

14. Deciphering the heterogeneity of neutrophil cells within circulation and the lung cancer microenvironment pre- and post-operation

    • Fangming Liu
    • Xuanqi Liu
    • Duojiao Wu

    RESEARCH Open access 06 February 2024 Article: 11

    

15. CD36 inhibition reduces non-small-cell lung cancer development through AKT-mTOR pathway

    • Hui Liu
    • Wentong Guo
    • Xiaoxiao Yang

    RESEARCH Open access 06 February 2024 Article: 10

    

16. Circular RNA circFCHO2(hsa_circ_0002490) promotes the proliferation of melanoma by directly binding to DND1

    • Yang Yang
    • Jianrui Li
    • Jianying Gu

    RESEARCH Open access 05 February 2024 Article: 9

    

17. METTL3 regulates TFRC ubiquitination and ferroptosis through stabilizing NEDD4L mRNA to impact stroke

    • Wenjie Su
    • Xiang Yu
    • Yi Li

    RESEARCH Open access 02 February 2024 Article: 8

    

18. circGRHPR inhibits aberrant epithelial-mesenchymal transformation progression of lung epithelial cells associated with idiopathic pulmonary fibrosis

    • Wensi Wu
    • Zhi Wang
    • Hui Tian

    RESEARCH Open access 25 January 2024 Article: 7

    

19. LOXL1 promotes tumor cell malignancy and restricts CD8 + T cell infiltration in colorectal cancer

    • Chenxi Li
    • Siqi Chen
    • Qian Yan

    RESEARCH Open access 25 January 2024 Article: 6

    

20. m⁶A modification mediates SLC3A2/SLC7A5 translation in 3-methylcholanthrene-induced uroepithelial transformation

    • Bixia Liu
    • Yifan Lv
    • Weidong Ji

    Research Open access 25 January 2024 Article: 5

    

21. TFEB and TFE3 cooperate in regulating inorganic arsenic-induced autophagy-lysosome impairment and immuno-dysfunction in primary dendritic cells

    • Guowei Xu
    • Huaguang Peng
    • Bing Li

    RESEARCH Open access 25 January 2024 Article: 4

    

22. POU6F1 promotes ferroptosis by increasing lncRNA-CASC2 transcription to regulate SOCS2/SLC7A11 signaling in gastric cancer

    • Jingyun Wang
    • Qiaoyu Jia
    • Hanbing Ning

    Research Open access 25 January 2024 Article: 3

    

23. Deficiency of copper responsive gene stmn4 induces retinal developmental defects

    • YuanYuan Jing
    • Yi Luo
    • Jing-Xia Liu

    RESEARCH Open access 22 January 2024 Article: 2

    

24. ARRB1 downregulates acetaminophen-induced hepatoxicity through binding to p-eIF2α to inhibit ER stress signaling

    • Yujun Luo
    • Yiming Lei
    • Bin Wu

    RESEARCH Open access 22 January 2024 Article: 1

    

25. Tumor cell-derived exosomes mediating hsa_circ_0001739/lncRNA AC159540.1 facilitate liver metastasis in colorectal cancer

    • Cai-Feng Yue
    • Ju-Gao Chen
    • Yun-Miao Guo

    ORIGINAL ARTICLE 14 November 2023 Pages: 2551 - 2568

    

26. Urinary extracellular vesicles prevent di-(2-ethylhexyl) phthalate-induced hypospadias by facilitating epithelial–mesenchymal transition via PFN2 delivery

    • Shibo Zhu
    • Xiangliang Tang
    • Wei Jia

    ORIGINAL ARTICLE 13 November 2023 Pages: 2569 - 2586

    

27. SUMOylation of RALY promotes vasculogenic mimicry in glioma cells via the FOXD1/DKK1 pathway

    • Shuo Cao
    • Di Wang
    • Xiaobai Liu

    RESEARCH Open access 31 October 2023 Pages: 3323 - 3340

    

28. Recent advances in pluripotent stem cell-derived cardiac organoids and heart-on-chip applications for studying anti-cancer drug-induced cardiotoxicity

    • Silin Liu
    • Chongkai Fang
    • Qingzhong Xiao

    REVIEW 27 October 2023 Pages: 2527 - 2549

    

29. NRF2 is essential for iron-overload stimulated osteoclast differentiation through regulation of redox and iron homeostasis

    • Jian Zhang
    • Lingyan Zhang
    • Shuguang Wu

    Research 19 October 2023 Pages: 3305 - 3321

    

30. GPC3-IL7-CCL19-CAR-T primes immune microenvironment reconstitution for hepatocellular carcinoma therapy

    • Li-Li Lu
    • Shu-xiu Xiao
    • Wei-Zhong Wu

    RESEARCH 19 October 2023 Pages: 3101 - 3119

    

31. Andrographolide attenuated MCT-induced HSOS via regulating NRF2-initiated mitochondrial biogenesis and antioxidant response

    • Zhenlin Huang
    • Zeqi Wu
    • Lili Ji

    RESEARCH 11 October 2023 Pages: 3269 - 3285

    

32. circSSPO boosts growth of esophageal squamous cell carcinoma through upregulation of micrRNA-6820-5p-mediated KLK8 and PKD1 expression

    • Qianhua Luo
    • Junzheng Li
    • Shuyao Zhang

    Research 09 October 2023 Pages: 3219 - 3234

    

33. Imatinib and M351-0056 enhance the function of VISTA and ameliorate the development of SLE via IFN-I and noncanonical NF-κB pathway

    • Lu Yang
    • Tingting Zhang
    • Jun Liu

    Research 07 October 2023 Pages: 3287 - 3304

    

34. Single-cell RNA sequencing reveals differences between force application and bearing in ankle cartilage

    • Junjie Wang
    • Zewen Sun
    • Yingze Zhang

    Research 03 October 2023 Pages: 3235 - 3253

    

35. Targeting autophagy with SAR405 alleviates doxorubicin-induced cardiotoxicity

    • Xiaofan Sun
    • Juan Du
    • Hui Zeng

    RESEARCH 28 September 2023 Pages: 3255 - 3267

    

36. Targeting the crosstalk of epigenetic modifications and immune evasion in nasopharyngeal cancer

    • Chin-King Looi
    • Lian-Chee Foong
    • Chun-Wai Mai

    REVIEW 27 September 2023 Pages: 2501 - 2526

    

37. LncRNA Tug1 relieves the steatosis of SelenoF-knockout hepatocytes via sponging miR-1934-3p

    • Wei Wang
    • Zhiruo Miao
    • Shiwen Xu

    Research 18 September 2023 Pages: 3175 - 3195

    

38. Loss of Dact2 alleviates cisplatin-induced nephrotoxicity through regulation of the Igfl-MAPK pathway axis

    • Changuk Kim
    • Woori Kwak
    • Jun-Won Yun

    Research 21 August 2023 Pages: 3197 - 3217

    

39. GALNT2, an O-glycosylating enzyme, is a critical regulator of radioresistance of non-small cell lung cancer: evidence from an integrated multi-omics analysis

    • Xiaoxia Dong
    • Yahui Leng
    • Li Shen

    Research 19 August 2023 Pages: 3159 - 3174

    

40. Correction to: Epigenetic regulation of LINC01270 in breast cancer progression by mediating LAMA2 promoter methylation and MAPK signaling pathway

    • Shaoying Li
    • Jiamei Hu
    • Yuan Duan

    Correction 14 August 2023 Pages: 3345 - 3345

41. USP7-mediated JUND suppresses RCAN2 transcription and elevates NFATC1 to enhance stem cell property in colorectal cancer

    • Yunli Chang
    • Lingling Chen
    • Ming Xu

    RESEARCH 03 August 2023 Pages: 3121 - 3140

    

42. Trps1 acts as a regulator of Sf-1 transcription and testosterone synthesis in mouse Leydig cells

    • Jiandong Sun
    • Xiuli Lian
    • Shie Wang

    RESEARCH 02 August 2023 Pages: 3141 - 3157

    

43. Hyperhomocysteinemia lowers serum testosterone concentration via impairing testosterone production in Leydig cells

    • Zhiyuan Su
    • Zhuoliang Liu
    • Jing Nie

    RESEARCH 27 July 2023 Pages: 3077 - 3100

    

44. Pyroptosis in neurodegenerative diseases: from bench to bedside

    • Ke-jia Wu
    • Wan-rong Wang
    • Rui-jie Zhang

    Review 26 July 2023 Pages: 2467 - 2499

    

45. Role of GSDM family members in airway epithelial cells of lung diseases: a systematic and comprehensive transcriptomic analysis

    • Xuanqi Liu
    • Linlin Zhang
    • Xiangdong Wang

    RESEARCH 18 July 2023 Pages: 2743 - 2760

    

46. Tungsten toxicity on kidney tubular epithelial cells induces renal inflammation and M1-macrophage polarization

    • Jonatan Barrera-Chimal
    • Nathalie Henley
    • Casimiro Gerarduzzi

    Research 27 June 2023 Pages: 3061 - 3075

    

47. Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells

    • Giada Carta
    • Wanda van der Stel
    • Paul Jennings

    RESEARCH Open access 23 June 2023 Pages: 3031 - 3059

    

48. Targeting epigenetic deregulations for the management of esophageal carcinoma: recent advances and emerging approaches

    • Parul Ahuja
    • Ritu Yadav
    • Lokesh Kadian

    Review 20 June 2023 Pages: 2437 - 2465

    

49. Brain pericytes in culture display diverse morphological and functional phenotypes

    • Lachlan S. Brown
    • Natalie E. King
    • Brad A. Sutherland

    RESEARCH Open access 16 June 2023 Pages: 2999 - 3014

    

50. The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells

    • Min Zhou
    • Joelle C. Boulos
    • Thomas Efferth

    RESEARCH Open access 16 June 2023 Pages: 2971 - 2997