1. Parallels and contrasts between iron and copper metabolism

   • Michael D. Garrick
   • Marco T. Núñez
   • Edward D. Harris

   OriginalPaper Pages: 1 - 8

2. The copper-iron chronicles: The story of an intimate relationship

   • Paul L. Fox

   OriginalPaper Pages: 9 - 40

3. DMT1: A mammalian transporter for multiple metals

   • Michael D. Garrick
   • Kevin G. Dolan
   • Laura M. Garrick

   OriginalPaper Pages: 41 - 54

4. Pretranslational control of Menkes disease gene expression

   • Edward D. Harris
   • Manchi C.M. Reddy
   • Mariela Cantera

   OriginalPaper Pages: 55 - 61

5. Brain iron uptake and homeostatic mechanisms: An overview

   • Joseph R. Burdo
   • James R. Connor

   OriginalPaper Pages: 63 - 75

6. Adventiously-bound redox active iron and copper are at the center of oxidative damage in Alzheimer disease

   • George Perry
   • Marta A. Taddeo
   • Mark A. Smith

   OriginalPaper Pages: 77 - 81

7. Iron-activated iron uptake: A positive feedback loop mediated by iron regulatory protein 1

   • Marto T. Núñez
   • Claudia Núñez-Millacura
   • Ricardo B. Maccioni

   OriginalPaper Pages: 83 - 90

8. Copper reduction by copper binding proteins and its relation to neurodegenerative diseases

   • Carlos Opazo
   • María Inés Barría
   • Nibaldo C. Inestrosa

   OriginalPaper Pages: 91 - 98

9. Prevention of free-radical mediated tissue damage and carcinogenesis induced by low-molecular-weight iron

   • Shigeru Okada

   OriginalPaper Pages: 99 - 101

10. Oxidative stress-mediated hepatotoxicity of iron and copper: Role of Kupffer cells

    • Luis A. Videla
    • Virginia Fernández
    • Patricia Varela

    OriginalPaper Pages: 103 - 111

11. Copper-binding proteins in human erythrocytes: Searching for potential biomarkers of copper over-exposure

    • Hernán Speisky
    • Paola Navarro
    • Inés Jiménez

    OriginalPaper Pages: 113 - 123

12. Role of nitric oxide in cellular iron metabolism

    • Sangwon Kim
    • Prem Ponka

    OriginalPaper Pages: 125 - 135

13. The Enterococcus hirae paradigm of copper homeostasis: Copper chaperone turnover, interactions, and transactions

    • Zen Huat Lu
    • Charles T. Dameron
    • Marc Solioz

    OriginalPaper Pages: 137 - 143

14. Iron and copper homeostasis and intestinal absorption using the Caco2 cell model

    • Maria C. Linder
    • Nora R. Zerounian
    • Rashmi Malpe

    OriginalPaper Pages: 145 - 160

15. The role of the placenta in iron transfer from mother to fetus and the relationship between iron status and fetal outcome

    • H.J. McArdle
    • R. Danzeisen
    • L. Gambling

    OriginalPaper Pages: 161 - 167

16. Copper exposure modifies the content and distribution of trace metals in mammalian cultured cells

    • Lucía Tapia
    • Miriam Suazo
    • Mauricio González

    OriginalPaper Pages: 169 - 174

17. Copper-induced trafficking of the Cu-ATPases: A key mechanism for copper homeostasis

    • Julian F.B. Mercer
    • Natalie Barnes
    • Roxana M. Llanos

    OriginalPaper Pages: 175 - 184

18. Yeast, a model organism for iron and copper metabolism studies

    • Jeane De Freitas
    • Henri Wintz
    • Chris Vulpe

    OriginalPaper Pages: 185 - 197

19. Copper exposure and potential biomarkers of copper metabolism

    • Magdalena Araya
    • Manuel Olivares
    • Ricardo Uauy

    OriginalPaper Pages: 199 - 204

20. Aceruloplasminemia, an inherited disorder of iron metabolism

    • Hiroaki Miyajima
    • Yoshitomo Takahashi
    • Satoshi Kono

    OriginalPaper Pages: 205 - 213

21. Iron-induced oxidative stress modify tau phosphorylation patterns in hippocampal cell cultures

    • José Tomás Egaña
    • Cristian Zambrano
    • Ricardo B. Maccioni

    OriginalPaper Pages: 215 - 223

22. Regulation of SLC11A3 by inflammation

    • David H. Haile

    OriginalPaper Pages: 225 - 241