Volume 41, Issue 2

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February 2014

Special Issue: Microbial Genome Mining

Issue Editors:

Brian O. Bachmann,
Steven G. Van Lanen,
Richard H. Baltz

26 articles in this issue

Sir David Alan Hopwood
Leonard Katz
Dedication 07 November 2013 Pages: 173 - 174
Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?
Brian O. Bachmann
Steven G. Van Lanen
Richard H. Baltz
Introductory Review 17 December 2013 Pages: 175 - 184
Importance of microbial natural products and the need to revitalize their discovery
Arnold L. Demain
Review 30 August 2013 Pages: 185 - 201
Challenges and triumphs to genomics-based natural product discovery
Paul R. Jensen
Krystle L. Chavarria
Nadine Ziemert
Perspective 09 October 2013 Pages: 203 - 209
Evolutionary concepts in natural products discovery: what actinomycetes have taught us
Janko Diminic
Antonio Starcevic
Jurica Zucko
Mini-Review 24 September 2013 Pages: 211 - 217
Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways
Gregory L. Challis
Review 10 December 2013 Pages: 219 - 232
Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters
Haruo Ikeda
Kazuo Shin-ya
Satoshi Omura
Review 29 August 2013 Pages: 233 - 250
Genome mining of Streptomyces ambofaciens
Bertrand Aigle
Sylvie Lautru
Jean-Luc Pernodet
Mini-Review 21 November 2013 Pages: 251 - 263
Identification of a vitamin D₃-specific hydroxylase genes through actinomycetes genome mining
Jun-Gyu Ban
Hyun-Bum Kim
Eung-Soo Kim
Original Article 10 October 2013 Pages: 265 - 273
Genome-guided discovery of diverse natural products from Burkholderia sp.
Xiangyang Liu
Yi-Qiang Cheng
Mini-Review 09 November 2013 Pages: 275 - 284
Merging chemical ecology with bacterial genome mining for secondary metabolite discovery
Maria I. Vizcaino
Xun Guo
Jason M. Crawford
Review 15 October 2013 Pages: 285 - 299
Strategies for mining fungal natural products
Philipp Wiemann
Nancy P. Keller
Review 22 October 2013 Pages: 301 - 313
Lessons learned from the transformation of natural product discovery to a genome-driven endeavor
Caitlin D. Deane
Douglas A. Mitchell
Review 19 October 2013 Pages: 315 - 331
Prospecting genomes for lasso peptides
Mikhail O. Maksimov
A. James Link
Review 19 October 2013 Pages: 333 - 344
Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways
Kou-San Ju
James R. Doroghazi
William W. Metcalf
Mini-Review 24 November 2013 Pages: 345 - 356
MbtH homology codes to identify gifted microbes for genome mining
Richard H. Baltz
Original Article 07 November 2013 Pages: 357 - 369
Triggers and cues that activate antibiotic production by actinomycetes
Hua Zhu
Stephanie K. Sandiford
Gilles P. van Wezel
Review 02 August 2013 Pages: 371 - 386
Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?
Yuriy Rebets
Elke Brötz
Andriy Luzhetskyy
Review 15 October 2013 Pages: 387 - 402
Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements
Kozo Ochi
Yukinori Tanaka
Shigeo Tojo
Review 15 October 2013 Pages: 403 - 414
Activating secondary metabolism with stress and chemicals
Vanessa Yoon
Justin R. Nodwell
Review 11 December 2013 Pages: 415 - 424
Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways
Juan Pablo Gomez-Escribano
Mervyn J. Bibb
Review Article 06 October 2013 Pages: 425 - 431
Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans
Junko Yaegashi
Berl R. Oakley
Clay C. C. Wang
Mini-Review 17 December 2013 Pages: 433 - 442
Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides
Christopher N. Boddy
Mini-Review 31 October 2013 Pages: 443 - 450
Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways
Jessica C. Albright
Anthony W. Goering
Neil L. Kelleher
Original Article 19 November 2013 Pages: 451 - 459
Predicting substrate specificity of adenylation domains of nonribosomal peptide synthetases and other protein properties by latent semantic indexing
Damir Baranašić
Jurica Zucko
Antonio Starcevic
Original Article 09 October 2013 Pages: 461 - 467
DNA assembly techniques for next-generation combinatorial biosynthesis of natural products
Ryan E. Cobb
Jonathan C. Ning
Huimin Zhao
Review 15 October 2013 Pages: 469 - 477

Volume 41, Issue 2

Sir David Alan Hopwood

Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

Importance of microbial natural products and the need to revitalize their discovery

Challenges and triumphs to genomics-based natural product discovery

Evolutionary concepts in natural products discovery: what actinomycetes have taught us

Exploitation of the Streptomyces coelicolor A3(2) genome sequence for discovery of new natural products and biosynthetic pathways

Genome mining of the Streptomyces avermitilis genome and development of genome-minimized hosts for heterologous expression of biosynthetic gene clusters

Genome mining of Streptomyces ambofaciens

Identification of a vitamin D₃-specific hydroxylase genes through actinomycetes genome mining

Genome-guided discovery of diverse natural products from Burkholderia sp.

Merging chemical ecology with bacterial genome mining for secondary metabolite discovery

Strategies for mining fungal natural products

Lessons learned from the transformation of natural product discovery to a genome-driven endeavor

Prospecting genomes for lasso peptides

Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways

MbtH homology codes to identify gifted microbes for genome mining

Triggers and cues that activate antibiotic production by actinomycetes

Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?

Activating the expression of bacterial cryptic genes by rpoB mutations in RNA polymerase or by rare earth elements

Activating secondary metabolism with stress and chemicals

Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways

Recent advances in genome mining of secondary metabolite biosynthetic gene clusters and the development of heterologous expression systems in Aspergillus nidulans

Bioinformatics tools for genome mining of polyketide and non-ribosomal peptides

Strain-specific proteogenomics accelerates the discovery of natural products via their biosynthetic pathways

Predicting substrate specificity of adenylation domains of nonribosomal peptide synthetases and other protein properties by latent semantic indexing

DNA assembly techniques for next-generation combinatorial biosynthesis of natural products

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