1. A historical perspective on familial cancer: results and vision of the Polyposis Center Project

   • Joji Utsunomiya
   • Takeo Iwama
   • Masami Arai

   REVIEW ARTICLE Pages: 215 - 231

2. Mechanism of carcinogenesis in familial tumors

   • Kazuo Tamura
   • Joji Utsunomiya
   • Takehira Yamamura

   REVIEW ARTICLE Pages: 232 - 245

3. Molecular genetic diagnosis of familial tumors

   • Naohiro Tomita
   • Michiei Oto

   REVIEW ARTICLE Pages: 246 - 256

4. Studies of familial tumors using models: genotype, phenotype, and dramatype in carcinogenesis

   • Okio Hino

   REVIEW ARTICLE Pages: 257 - 261

5. Association of HNPCC and endometrial cancers

   • Kouji Banno
   • Nobuyuki Susumu
   • Shiro Nozawa

   REVIEW ARTICLE Pages: 262 - 269

6. Familial breast and ovarian cancers

   • Masami Arai
   • Joji Utsunomiya
   • Yoshio Miki

   REVIEW ARTICLE Pages: 270 - 282

7. Recent advances in ideas on the molecular pathology and clinical aspects of Von Hippel-Lindau disease

   • Taro Shuin
   • Ichiro Yamazaki
   • Shingo Ashida

   REVIEW ARTICLE Pages: 283 - 287

8. Molecular biology of Werner syndrome

   • Akira Shimamoto
   • Masanobu Sugimoto
   • Yasuhiro Furuichi

   REVIEW ARTICLE Pages: 288 - 298

9. Chemoprevention of carcinogenesis in familial tumors

   • Hideki Ishikawa

   REVIEW ARTICLE Pages: 299 - 303

10. Comprehensive genetics clinic for familial tumors: proposal for a suitable system in Japan

    • Yoshimitsu Fukushima
    • Akihiro Sakurai

    REVIEW ARTICLE Pages: 304 - 307

11. A clinical overview of familial adenomatous polyposis derived from the database of the Polyposis Registry of Japan

    • Takeo Iwama
    • Kazuo Tamura
    • The Polyposis Committee, Japanese Society for Cancer of the Colon and Rectum

    REVIEW ARTICLE Pages: 308 - 316

12. Postoperative adjuvant chemotherapy with cisplatin, cyclophosphamide, and anthracycline (doxorubicin, epirubicin, pirarubicin) for endometrial cancer

    • Hideaki Yahata
    • Toshio Hirakawa
    • Hitoo Nakano

    ORIGINAL ARTICLE Pages: 317 - 321

13. Biological features of sporadic colorectal carcinoma with high-frequency microsatellite instability: special reference to tumor proliferation and apoptosis

    • Shinjiro Mori
    • Yutaka Ogata
    • Kazuo Shirouzu

    ORIGINAL ARTICLE Pages: 322 - 329

14. PIVKA-II-producing advanced gastric cancer

    • Shigetsugu Takano
    • Ichiro Honda
    • Masaru Miyazaki

    CASE REPORT Pages: 330 - 333

15. Invasive ductal carcinoma within a fibroadenoma of the breast

    • Hajime Abe
    • Kazuyoshi Hanasawa
    • Ryoji Kushima

    CASE REPORT Pages: 334 - 338

16. Spontaneous regression of recurrent squamous cell carcinoma of the tongue

    • Ryoichi Oya
    • Kunio Ikemura

    CASE REPORT Pages: 339 - 342