1. Clinical practice guideline for the treatment of malignant ascites: section summary in Clinical Practice Guideline for peritoneal dissemination (2021)

   • Keisuke Matsusaki
   • Kuniaki Aridome
   • Joji Kitayama

   Special Article Open access 20 November 2021 Pages: 1 - 6

   

2. Cancer in adolescents and young adults in Japan: epidemiology and cancer strategy

   • Kayo Nakata
   • Eiso Hiyama
   • Isao Miyashiro

   Invited Review Article Open access 15 November 2021 Pages: 7 - 15

   

3. Current status of AYA-generation breast cancer: trends worldwide and in Japan

   • Manabu Futamura
   • Kazuhiro Yoshida

   Invited Review Article 18 December 2021 Pages: 16 - 24

   

4. Current state of fertility preservation for adolescent and young adult patients with gynecological cancer

   • Tatsuru Ohara
   • Shiho Kuji
   • Nao Suzuki

   Invited Review Article 15 November 2021 Pages: 25 - 34

   

5. Critical appraisal of epigenetic regulation of galectins in cancer

   • Ashita Gadwal
   • Anupama Modi
   • Purvi Purohit

   Review Article 15 October 2021 Pages: 35 - 44

   

6. Key promoters of tumor hallmarks

   • Keywan Mortezaee
   • Jamal Majidpoor

   Review Article 13 November 2021 Pages: 45 - 58

   

7. Pretreatment clinical and hematologic prognostic factors of metastatic urothelial carcinoma treated with pembrolizumab: a systematic review and meta-analysis

   • Takafumi Yanagisawa
   • Keiichiro Mori
   • Shahrokh F. Shariat

   Review Article Open access 10 November 2021 Pages: 59 - 71

   

8. Presence of serum RalA and serum p53 autoantibodies in 1833 patients with various types of cancers

   • Tatsuki Nanami
   • Isamu Hoshino
   • Hideaki Shimada

   Original Article 11 October 2021 Pages: 72 - 76

   

9. The Real-World status and risk factors for a poor prognosis in elderly patients with primary central nervous system malignant lymphomas: a multicenter, retrospective cohort study of the Tohoku Brain Tumor Study Group

   • Kenichiro Asano
   • Yoji Yamashita
   • Teiji Tominaga

   Original Article 12 October 2021 Pages: 77 - 94

   

10. Outcomes of long-term nivolumab and subsequent chemotherapy in Japanese patients with head and neck cancer: 2-year follow-up from a multicenter real-world study

    • Ryuji Yasumatsu
    • Yasushi Shimizu
    • Akihiro Homma

    Original Article Open access 13 November 2021 Pages: 95 - 104

    

11. Heterogeneous distribution of PD-L1 expression in the IASLC/ATS/ERS classification of lung adenocarcinoma

    • Dachuan Zhang
    • Xie Gao
    • Qing Li

    Original Article 06 October 2021 Pages: 105 - 111

    

12. Osimertinib in poor performance status patients with T790M-positive advanced non-small-cell lung cancer after progression of first- and second-generation EGFR-TKI treatments (NEJ032B)

    • Yukari Tsubata
    • Kana Watanabe
    • Takeshi Isobe

    Original Article Open access 13 October 2021 Pages: 112 - 120

    

13. Large and diffuse ductal carcinoma in situ: potentially lethal subtypes of “preinvasive” disease

    • Thomas J. O’Keefe
    • Olivier Harismendy
    • Anne M. Wallace

    Original Article 07 October 2021 Pages: 121 - 130

    

14. Preoperative transferrin level is a novel indicator of short- and long-term outcomes after esophageal cancer surgery

    • Taishi Yamane
    • Hiroshi Sawayama
    • Hideo Baba

    Original Article 29 September 2021 Pages: 131 - 140

    

15. Preoperative sarcopenia is a poor prognostic factor in lower rectal cancer patients undergoing neoadjuvant chemoradiotherapy: a retrospective study

    • Shinya Abe
    • Kazushige Kawai
    • Soichiro Ishihara

    Original Article 06 November 2021 Pages: 141 - 153

    

16. Pembrolizumab plus axitinib versus sunitinib in metastatic renal cell carcinoma: outcomes of Japanese patients enrolled in the randomized, phase III, open-label KEYNOTE-426 study

    • Satoshi Tamada
    • Chihiro Kondoh
    • Hirotsugu Uemura

    Original Article Open access 20 November 2021 Pages: 154 - 164

    

17. Chronological transition in outcome of second-line treatment in patients with metastatic urothelial cancer after pembrolizumab approval: a multicenter retrospective analysis

    • Teruki Isobe
    • Taku Naiki
    • Takahiro Yasui

    Original Article 11 October 2021 Pages: 165 - 174

    

18. Sarcopenia is associated with survival in patients with urothelial carcinoma treated with systemic chemotherapy

    • Ryutaro Shimizu
    • Masashi Honda
    • Atsushi Takenaka

    Original Article 04 October 2021 Pages: 175 - 183

    

19. How long is long enough to secure disease control after low-dose-rate brachytherapy in combination with other modalities in intermediate-risk, localized prostate cancer?

    • Fumihiko Urabe
    • Takahiro Kimura
    • Shin Egawa

    Original Article 02 October 2021 Pages: 184 - 193

    

20. Deferred radical prostatectomy in patients who initially elected for active surveillance: a multi-institutional, prospective, observational cohort of the PRIAS-JAPAN study

    • Yoichiro Tohi
    • Takuma Kato
    • Mikio Sugimoto

    Original Article 02 October 2021 Pages: 194 - 201

    

21. Comparison of treatment outcomes of pelvis external radiotherapy with and without vaginal brachytherapy for cervical cancer patients with positive or close vaginal resected margins

    • Yun Hee Lee
    • Yeon Sil Kim
    • Sung Hwan Kim

    Original Article 22 October 2021 Pages: 202 - 212

    

22. Phase 2 study of axicabtagene ciloleucel in Japanese patients with relapsed or refractory large B-cell lymphoma

    • Koji Kato
    • Shinichi Makita
    • Kiyohiko Hatake

    Original Article Open access 01 October 2021 Pages: 213 - 223

    

23. A phase 2, open-label, multicenter study of ixazomib plus lenalidomide and dexamethasone in adult Japanese patients with relapsed and/or refractory multiple myeloma

    • Shinsuke Iida
    • Tohru Izumi
    • Makoto Sasaki

    Original Article Open access 02 October 2021 Pages: 224 - 233

    

24. An analysis of tumor-related skin temperature differences in malignant soft-tissue tumors

    • Akiyoshi Shimatani
    • Manabu Hoshi
    • Hiroaki Nakamura

    Original Article 10 October 2021 Pages: 234 - 243

    

25. Correction to: An analysis of tumor-related skin temperature differences in malignant soft-tissue tumors

    • Akiyoshi Shimatani
    • Manabu Hoshi
    • Hiroaki Nakamura

    Correction 17 October 2021 Pages: 244 - 244

26. Changes of cancer diagnosis disclosure to children in Japan in the last 20 years

    • Hiroki Hori
    • Asuka Ohta
    • Kyoko Kobayashi

    Original Article 01 October 2021 Pages: 245 - 252

    

27. Clinical impact of primary tumour ¹²³ImIBG response to induction chemotherapy in children with high-risk neuroblastoma

    • Elwira Szychot
    • Daniel Morgenstern
    • Lorenzo Biassoni

    Original Article 09 October 2021 Pages: 253 - 261

    

28. Correction to: Medical guidelines for Li–Fraumeni syndrome 2019, version 1.1

    • Tadashi Kumamoto
    • Fumito Yamazaki
    • Yukiko Tsunematsu

    Correction Open access 03 December 2021 Pages: 262 - 263

29. Retraction Note to: Inhibition of TMEM16A suppresses growth and induces apoptosis in hepatocellular carcinoma

    • Chuantao Zhang
    • Jianxiang Liu
    • Yufeng Xing

    Retraction Note 13 November 2021 Pages: 264 - 264