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Gene Targeting Using Peptide Nucleic Acid

  • Protocol
Book cover Oligonucleotide Synthesis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 288))

Abstract

A brief overview of the properties of the deoxyribonucleic acid mimic peptide nucleic acid (PNA) is given, and the recent progress in cellular delivery of PNA and of using PNA oligomers for antisense and antigene gene targeting is presented.

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Authors and Affiliations

  1. Department of Medical Biochemistry and Genetics, The Panum Institute, University of Copenhagen, Copenhagen, Denmark

    Peter E. Nielsen

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  1. Peter E. Nielsen
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Editors and Affiliations

  1. Rega Institute, Medicinal Chemistry Lab, Katholieke Universiteit Leuven, Leuven, Belgium

    Piet Herdewijn

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© 2005 Humana Press Inc.

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Nielsen, P.E. (2005). Gene Targeting Using Peptide Nucleic Acid. In: Herdewijn, P. (eds) Oligonucleotide Synthesis. Methods in Molecular Biology, vol 288. Humana Press. https://doi.org/10.1385/1-59259-823-4:343

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  • DOI: https://doi.org/10.1385/1-59259-823-4:343

  • Publisher Name: Humana Press

  • Print ISBN: 978-1-58829-233-9

  • Online ISBN: 978-1-59259-823-6

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