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Chemokine Protocols pp 209–222Cite as

Chemokine Inhibition of HIV Infection

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Part of the book series: Methods in Molecular Biology ((MIMB,volume 138))

Abstract

Human immunodeficiency virus (HIV) is a member of the retro virus family, classified under the lentivirus genus. Retroviruses are enveloped RNA viruses, which contain a core of capsid proteins, viral RNA, and enzymes. All infectious retroviral virions contain an enzyme, reverse transcriptase, which catalyzes the formation of a complementary DNA strand from an RNA template. A double-stranded DNA copy of the viral RNA genome (proviral DNA) may then be integrated into and replicated with the host cell genome.

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Author information

Authors and Affiliations

  1. Department of Molecular Pathology, Windeyer Institute of Medical Sciences, Royal Free and University College Medical School University College London, London, UK

    Jacqueline D. Reeves & Graham Simmons

Authors
  1. Jacqueline D. Reeves
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  2. Graham Simmons
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Editors and Affiliations

  1. Serono Pharmaceutical Research Institute, Geneva, Switzerland

    Amanda E. I. Proudfoot , Timothy N. C. Wells  & Christine A. Power ,  & 

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© 2000 Humana Press Inc.

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Reeves, J.D., Simmons, G. (2000). Chemokine Inhibition of HIV Infection. In: Proudfoot, A.E.I., Wells, T.N.C., Power, C.A. (eds) Chemokine Protocols. Methods in Molecular Biology, vol 138. Humana Press. https://doi.org/10.1385/1-59259-058-6:209

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  • DOI: https://doi.org/10.1385/1-59259-058-6:209

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-722-9

  • Online ISBN: 978-1-59259-058-2

  • eBook Packages: Springer Protocols

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