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Isolation and Detection of Microcystins and Nodularins, Cyanobacterial Peptide Hepatotoxins

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Bacterial Toxins: Methods and Protocols

Part of the book series: Methods in Molecular Biology™ ((MIMB,volume 145))

Abstract

Some species and strains within the freshwater cyanobacterial (blue-green algal) genera Microcystis, Oscillatoria (also known as Planktothrix), Anabaena, and Nostoc are known to produce cyclic heptapeptide liver toxins, microcystins. Closely related toxic cyclic pent ape ptides, nodularins, have been isolated from the brackish water cyanobacterium Nodularia spumigena. In addition, some cyanobacteria produce neurotoxic compounds such as anatoxin-a, anatoxin-a(s), and saxitoxins. Recent reviews of the chemical and biological properties of microcystins, nodularins, and other cyanobacterial toxins are given in refe. (1–4).

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Author information

Authors and Affiliations

  1. Department of Biochemistry and Pharmacy, Åbo Akademi University, Turku, Finland

    Jussi Meriluoto

  2. School of Applied Sciences, Robert Gordon University, Aberdeen, UK

    Linda Lawton

  3. Laboratory of Instrumental Analytical Chemistry Faculty of Pharmacy, Meijo University, Nagoya, Japan

    Ken-ichi Harada

Authors
  1. Jussi Meriluoto
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  2. Linda Lawton
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  3. Ken-ichi Harada
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Editor information

Editors and Affiliations

  1. Research Center Borstel, Germany

    Otto Holst

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© 2000 Humana Press Inc.

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Meriluoto, J., Lawton, L., Harada, Ki. (2000). Isolation and Detection of Microcystins and Nodularins, Cyanobacterial Peptide Hepatotoxins. In: Holst, O. (eds) Bacterial Toxins: Methods and Protocols. Methods in Molecular Biology™, vol 145. Humana Press. https://doi.org/10.1385/1-59259-052-7:65

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  • DOI: https://doi.org/10.1385/1-59259-052-7:65

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-604-8

  • Online ISBN: 978-1-59259-052-0

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