Abstract
As cancer treatment options broaden, there is a corresponding increase m the need for Improved methods of detecting various stages and forms of the disease. Only through the use of highly sensitive and discriminating dtagnostic tests can a rational and Informed decision be made from among the clinical interventions available to the physician. The case of prostate cancer is an ideal paradigm of this challenging problem. As with many other types of solid tumors, complete cure can frequently be achieved through established methods of treatment if the malignancy is organ-confined. However, accurate staging of the disease when gross metastases are not evident 1s problemattc because the techniques in use have poor sensitivities for micrometastatic disease. Consequently, since the optimal treatment strategy is different for primary and meta-static disease, the patient may not receive the best initial treatment.
Keywords
- Micrometastatic Disease
- Ethidium Bromide Solution
- Master Mixture
- Cell Preparation Tube
- Nontarget Sequence
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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© 1998 Humana Press Inc, Totowa, NJ
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Vessella, R.L., Corey, E. (1998). Detection of Prostate-Cancer Cells in Blood and Bone Marrow by RT-PCR. In: Hanausek, M., Walaszek, Z. (eds) Tumor Marker Protocols. Methods in Molecular Medicine™, vol 14. Springer, Totowa, NJ. https://doi.org/10.1385/0-89603-380-5:357
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DOI: https://doi.org/10.1385/0-89603-380-5:357
Publisher Name: Springer, Totowa, NJ
Print ISBN: 978-0-89603-380-1
Online ISBN: 978-1-59259-598-3
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