Abstract
It is shown that the trifluoroacetylation of 9-methylcarbazole proceeds regio-specifically in the 3 position of the ring. 1,1,1-Tris(9-methyl-3-carbazolyl)-2,2,2-trifluoroethane and 1,1,1′,1′-tetrakis(9-methyl-3-carbazolyl)-2,2,2,2′,2′,-2′-hexafluorodiethyl ether were also isolated from the reaction mixture. Bis(trifluoroacetyl) derivatives were not detected. Only a 3-trifluoroacetyl derivative is formed when the reaction is carried out by heating in the presence of pyridine.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 640–642, May, 1984.
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Sirotkina, E.E., Moskalev, N.V. & Shabotkin, I.G. Trifluoroacetylation of 9-methylcarbazole. Example of the formation of a triarylfluoroethane in the heterocyclic series. Chem Heterocycl Compd 20, 512–514 (1984). https://doi.org/10.1007/BF00514303
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DOI: https://doi.org/10.1007/BF00514303