Abstract
To understand the variations in optic disc topography that may affect the local susceptibility of nerve fibers to glaucomatous damage, we evaluated the correlations between optic disc topography and selected ocular parameters in 210 normal eyes of healthy Japanese. In the total study group, eyes with a longer axial length had a longer distance between the disc and foveola, a larger index of ovalness and a larger disc (P < 0.01). A longer disc-foveola distance correlated with a larger index of ovalness (P<0.01). The optic discs of severely myopic eyes had a considerably different structure from other eyes. Eyes with a tilted optic disc were unique in that the area of the optic disc was not large despite a positive correlation with long axial length (P<0.01) a long disc foveola distance (P<0.01), and a large index of ovalness (P<0.01). Eyes with a rotated optic disc were another special case. This eye type correlated in a contradictory fashion with two parameters: a large axial length (P<0.01) and a short disc-foveola distance (P<0.01). These findings suggest that changes in optic disc topography or susceptibility to glaucomatous damage correlate with selected ocular parameters but are not completely parallel.
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References
Apple DJ, Rabb MF, Walsh PM (1982) Congenital anomalies of the optic disc. Surv Ophthalmol 27:3–41
Armaly MF (1967) Genetic determination of cup/disc ratio of the optic nerve. Arch Ophthalmol 78:35–43
Beck RW, Servais GE, Hayreh SS (1987) Anterior ischemic optic neuropathy. IX. Cup-to-disc ratio and its role in pathogenesis. Ophthalmology 94:1503–1508
Bishop KI, Werner EB, Krupin T, Kozart DM, Beck SR, Nunan FA, Wax MB (1988) Variability and reproducibility of optic disc topographic measurement with the Rodenstock optic nerve head analyzer. Am J Ophthalmol 106:696–702
Britton RJ, Drance SM, Schulzer M, Douglas GR, Morrison DK (1987) The area of the neuroretinal rim of the optic nerve in normal eyes. Am J Ophthalmol 103:497–504
Chi T, Ritch R, Stickler D, Pitman B, Tsai C, Hsieh FY (1989) Racial differences in optic nerve head parameters. Arch Ophthalmol 107:836–839
Chihara E, Chihara K (1992) Apparent cleavage of the retinal nerve fiber layer in normal eyes with high myopia. Graefe's Arch Clin Exp Ophthalmol 230:416–420
Chihara E, Honda Y (1992) Preservation of nerve fiber layer by retinal vessels in glaucoma. Ophthalmology 99:208–214
Chihara E, Honda Y (1992) Multiple retinal nerve fiber layer defects in glaucoma. Graefe's Arch Clin Exp Ophthalmol 230:201–205
Chihara E, Sawada A (1990) Atypical nerve fiber layer defects in high myopes with high-tension glaucoma. Arch Ophthalmol 108:228–232
Chihara E, Takahara S (1993) Positive correlation between rotation of the optic disc and location of glaucomatous scotomata. In: Mills RP (ed) Perimetry Update 1992/1993, Kugler, Amsterdam, pp 199–205
Chihara E, Tanihara H (1992) Parameters associated with papillomacular bundle defects in glaucoma. Graefe's Arch Clin Exp Ophthalmol 230:511–517
Curtin B (1985) Adult progression of myopia. In: Curtin B (ed) The myopia. Harper & Row, Philadelphia, pp 394–400
Fledelius HC (1988) Refraction and eye size in the elderly: a review based on literature, including own results. Acta Ophthalmol (Copenh) 66:241–248
Hernandez MR, Igoe F, Neufeld AH (1986) Extracellular matrix of the human optic nerve head. Am J Ophthalmol 102:139–148
Ishii K (1951) Optic disc diameter in Japanese. Acta Soc Ophthalmol Jpn 55:242–243
Jonas JB, Gusek GC, Naumann GOH (1988) Optic disc, cup and neuroretinal rim size configuration and correlations in normal eyes. Invest Ophthalmol Vis Sci 29:1151–1158
Jonas JB, Gusek GC, Naumann GOH (1988) Optic disc morphometry in high myopia. Graefe's Arch Clin Exp Ophthalmol 226:587–590
Levene RZ (1982) Unusual optic discs in primary open-angle glaucoma. Ann Ophthalmol 14:617–620
Littmann H (1982) Zur Bestimmung der wahren Größe eines Objektes auf dem Hintergrund des lebenden Auges. Klin Monatsbl Augenheilkd 180:286–289
Perkins ES, Phelps CD (1982) Open angle glaucoma, ocular hypertension, low tension glaucoma and refraction. Arch Ophthalmol 100:1464–1467
Quigley HA, Addicks EM (1981) Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage. Arch Ophthalmol 99:137–143
Quigley HA, Brown AE, Morrison JD, Drance SM (1990) The size and shape of the optic disc in normal human eyes. Arch Ophthalmol 108:51–57
Shiose Y, Kitazawa Y, Tsukahara S, Akamatsu T, Mizokami K, Futa R, Katsushima H, Kosaki H (1991) Epidemiology of glaucoma in Japan: a nationwide survey. Jpn J Ophthalmol 35:133–155
Szily A von (1922) Ueber den Conus in heterotypischer Richtung. Albrecht v. Graefe's Arch Ophthalmol 110: 183–291
Tanaka Y, Tarumi T, Wakimoto K (1984) Handbook for statistic analysis by a personal computer. Kyoritsu Co, Tokyo, pp 1–142
Tsai CS, Ritch R, Shin DH, Wan JY, Chi T (1992) Age-related decline of disc rim area in visually normal subjects. Ophthalmology 99:29–35
Weiss AH, Ross EA (1992) Axial myopia in eyes with optic nerve hypoplasia. Graefe's Arch Clin Exp Ophthalmol 230:372–377
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Chihara, E., Chihara, K. Covariation of optic disc measurements and ocular parameters in the healthy eye. Graefe's Arch Clin Exp Ophthalmol 232, 265–271 (1994). https://doi.org/10.1007/BF00194475
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DOI: https://doi.org/10.1007/BF00194475