Continuous Multi Chemical Processing in 2D and 3D Microchannel Networks on Chip

Abstract

We have established three methods for enabling integration of general chemical systems onto microchips. One method is continuous flow chemical processing for realizing multistep chemical processing in liquid microspace. Another method is thermal lens microscopy for ultrasensitive determination of non-fluorescent molecules. The third method is construction of 3D microchannel networks. Appling these methods, any kind of chemical system, including analytical and synthetic, can, in principle, be designed and integrated onto microchips. These methodologies and some examples of micro-analytical, synthetic, and combinatorial synthetic systems will be presented.