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Genetica dell’osteoporosi, dell’osteopetrosi e dell’osteogenesi imperfetta

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Osteoporosi e malattie metaboliche dell’osso

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L’osteoporosi (OP) rientra in un ampio spettro di patologie che sono comunemente indicate come complesse e alia cui patogenesi concorrono molteplici fattori, genetici e ambientali. La componente genetica ha un notevole impatto sulla predisposizione all’OP ed è molto probabile che molti geni, ciascuno con un effetto moderato, siano coinvolti. Questo ha fortemente limitato l’identificazione di alcuni degli effetti genetici a specifici sottogruppi della popolazione.

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Authors and Affiliations

  1. Dipartimento di Medicina Interna, Università degli Studi di Firenze, Firenze

    Laura Masi & Alberto Falchetti

  2. Dipartimento di Medicina Interna, Facoltà di medicina e chirurgia, Università degli Studi di Firenze, Firenze

    Maria Luisa Brandi

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  1. Laura Masi
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  2. Alberto Falchetti
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Masi, L., Falchetti, A., Brandi, M.L. (2009). Genetica dell’osteoporosi, dell’osteopetrosi e dell’osteogenesi imperfetta. In: Osteoporosi e malattie metaboliche dell’osso. Springer, Milano. https://doi.org/10.1007/978-88-470-1357-5_24

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