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Pyridinderivate

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Bausteine des Tierkörpers I

Part of the book series: Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse ((HOPPE-SEYLER))

Zusammenfassung

Historisches. Im Jahre 1926 beschrieben Goldberger und Lillie 1 das Auftreten einer charakteristischen Hauterkrankung (Dermatitis) bei Ratten, die mit vitamin B2-freier Nahrung gefüttert wurden. GYÖRGY2 erkannte, daß dieeigentliche Ursache dieser Avitaminose durch einen bisher unbekannten Faktor (Ratten-Antidermatitisfaktor oder Anti-Akrodynie-Rattenfaktor) bedingt war; er wurde als Vitamin B6 bezeichnet. 1938 gelang es mehreren Forschergruppen fast gleichzeitig und unabhängig voneinander, das reine krystallisierte Vitamin B6 zu isolieren 3-7 und, i Jahr später, es in seiner Konstitution aufzuklären und zu svnthetisieren 8-12.

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H.-J. Bielig G. Birkofer K. Dimroth K. Heyns L. Jaenicke J. Kebrle E. Klenk K. Lang H. Lieb C. Martius A. Mondon E. Müller G. Oertel H. A. Offe Th. Ploetz R. Reuber J. Schmidt-Thomé W. Schöniger R. Tschesche F. Turba H. Weil-Malherbe

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Kebrle, J. (1955). Pyridinderivate. In: Bielig, HJ., et al. Bausteine des Tierkörpers I. Handbuch der Physiologisch- und Pathologisch-Chemischen Analyse. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-28629-6_17

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