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Cytostaseversuch an soliden Transplantationstumoren auf der Chorioallantoismembran von Hühnerembryonen

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Alkylantien, Fremdstoffmetabolismen, Cancerostase

Part of the book series: Forschungsberichte des Landes Nordrhein-Westfalen ((FOLANW))

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Zusammenfassung

Die in mehreren der vorausgegangenen Kapiteln behandelten und auch von uns über viele Jahre angewandten bakteriometrischen Methoden sind nicht die einzigen Möglichkeiten, cytostatische Effekte an biologischen Modellen zu messen. Sie sind vielmehr nur als eine Art Vorauswahlverfahren anzusehen. Cytostatisch aktive Verbindungen müssen dann auch an Modellen geprüft werden, die “menschenkrebsnäher” liegen als die bakteriometrischen. Hierzu haben sich im Laufe der Zeit einige Messmethoden mit einzelligen und mehrzelligen soliden “Impftumoren” entwickelt. Es ist hier nicht der Ort, diese Verfahren zu beschreiben und ihre Vorzüge oder Nachteile zu diskutieren, die schliesslich jeder biologische Test impliziert.

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    Prof. Dr. Hermann Matthias Rauen

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Rauen, H.M. (1973). Cytostaseversuch an soliden Transplantationstumoren auf der Chorioallantoismembran von Hühnerembryonen. In: Alkylantien, Fremdstoffmetabolismen, Cancerostase. Forschungsberichte des Landes Nordrhein-Westfalen. VS Verlag für Sozialwissenschaften, Wiesbaden. https://doi.org/10.1007/978-3-322-88148-9_6

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