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Is Focal Prostate Therapy Just Psychotherapy? Surveillance Versus Focal Therapy: Pros and Cons

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Focal Therapy of Prostate Cancer

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Abstract

Prostate focal therapy is to treat only the cancer site in the prostate. This new policy for treating prostate cancer is a potential bridge between active surveillance and the more aggressive treatment modalities. This treatment has been defined as the “complete ablation for all clinically significant foci within the prostate using a minimally invasive technique with preservation of the sphincter, normal grand tissue and the neurovascular bundles.”

The sources of energy to treat cancer focally can be cryotherapy, high-intensity focused ultrasound (HIFU), both high-dose-rate (HDR) brachytherapy and low-dose-rate (LDR) brachytherapy, radiotherapy, and thermotherapy.

What is most important to perform focal therapy is to diagnose the character of cancer accurately and to recognize the exact position of the cancer site.

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References

  1. Kakehi Y, Takegami Y, Suzukamo Y, et al. Health related quality of life in Japanese men with localized prostate cancer treated with current multiple modalities assessed by a newly developed Japanese version of the expanded prostate cancer index composite. J Urol. 2007;177(5):1856–61.

    Article  PubMed  Google Scholar 

  2. Eastham JA, Scardino PT. Expectant management of prostate cancer. In: Wein AJ, editor. Cambel-Walsh urology. 9th ed. Philadelphia: Saunders; 2007. p. 2947–55.

    Google Scholar 

  3. Parker C. Active surveillance of early prostate cancer: rationale, initial results and future developments. Prostate Cancer Prostatic Dis. 2004;7(3):184–7.

    Article  CAS  PubMed  Google Scholar 

  4. Crawford ED, Barqawi AB. Targeted focal therapy: a minimally invasive ablation technique for early prostate cancer. Oncology. 2007;21(1):27–32.

    PubMed  Google Scholar 

  5. Sullivan KF, Crawford ED. Target focal therapy for prostate cancer: a review of the literature. Ther Adv Urol. 2009;1(3):149–59.

    Article  PubMed Central  PubMed  Google Scholar 

  6. Iberti CT, Mohamed N, Palese MA. A review of focal therapy techniques in prostate cancer: clinical results for high-intensity focused ultrasound and focal cryoablation. Rev Urol. 2011;13(4):196–202.

    Google Scholar 

  7. Kamrava M, Chung MP, Kayode O, et al. Focal high-dose-rate brachytherapy: a dosimetric comparison of hemigland vs. conventional whole-gland treatment. Brachytherapy. 2013;12(5):434–41.

    Article  PubMed  Google Scholar 

  8. Cosset JM, Cathelineau X, Wakil G, et al. Focal brachytherapy for selected low-risk prostate cancers: a pilot study. Brachytherapy. 2013;12(4):331–7.

    Article  PubMed  Google Scholar 

  9. Barqawi AB, Krughoff KJ, Eid K. Current challenges in prostate cancer management and the rationale behind targeted focal therapy. Adv Urol. 2012. doi:10.1155/2012/862639.

    PubMed Central  PubMed  Google Scholar 

  10. Lee DH, Koo KC, Lee SH, et al. Low-risk prostate cancer patients without visible tumor (T1c) on multi-parametric MRI could qualify for active surveillance candidate even if they did not meet inclusion criteria of active surveillance protocol. Jpn J Clin Oncol. 2013;43(5):553–8.

    Article  CAS  PubMed  Google Scholar 

  11. Sartor AO, Hricak H, Wheeler TM, et al. Evaluating localized prostate cancer and identifying candidates for focal therapy. Urology. 2008;72(6 suppl):12–24.

    Article  Google Scholar 

  12. Meiers I, Waters D, Bostwick D. Preoperative prediction of multifocal prostate cancer and application of focal therapy: review 2007. Urology. 2007;70(6 suppl):3–8.

    Article  PubMed  Google Scholar 

  13. Wise A, Stamey T, McNeal J, et al. Morphologic and clinical significance of multifocal prostate cancer in radical prostatectomy specimens. Urology. 2002;60(2):264–9.

    Article  PubMed  Google Scholar 

  14. Ward JF, Pisters LL. Considerations for patient selection for focal therapy. Ther Adv Urol. 2013;5(6):330–7.

    Article  PubMed Central  PubMed  Google Scholar 

  15. Kakehi Y. Active surveillance as a practical strategy to differentiate lethal and non-lethal prostate cancer subtypes. Asian J Androl. 2012;14(3):361–4.

    Article  PubMed Central  PubMed  Google Scholar 

  16. Bill-Axelson A, Holmberg L, Ruutu M. Radical prostatectomy versus watchful waiting in early prostate cancer. N Engl J Med. 2005;352(19):1977–84.

    Article  CAS  PubMed  Google Scholar 

  17. Choo R, Klotz L, Danjoux C. Feasible study: watchful waiting for localized low to intermediate grade prostate carcinoma with selective delayed intervention based on prostate specific antigen, histological and/or clinical progression. J Urol. 2002;167(4):1664–9.

    Article  PubMed  Google Scholar 

  18. Patel MI, DeConcini DT, Lopez-Corona E, et al. An analysis of men with clinically localized prostate cancer who deferred definitive therapy. J Urol. 2004;171(4):1520–4.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Urology, National Hospital Organization Tokyo Medical Center, 2-5-1 Higashigaoka Meguro-ku, Tokyo, 152-8902, Japan

    Shiro Saito MD

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  1. Shiro Saito MD
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Correspondence to Shiro Saito MD .

Editor information

Editors and Affiliations

  1. Department of Urology, Klinikum München-Harlaching, München, Germany

    Stefan Thüroff

  2. Department of Urology, University of Regensburg Caritas Hospital St. Josef, Regensburg, Germany

    Christian G. Chaussy

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© 2015 Springer International Publishing Switzerland

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Saito, S. (2015). Is Focal Prostate Therapy Just Psychotherapy? Surveillance Versus Focal Therapy: Pros and Cons. In: Thüroff, S., Chaussy, C. (eds) Focal Therapy of Prostate Cancer. Springer, Cham. https://doi.org/10.1007/978-3-319-14160-2_2

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  • DOI: https://doi.org/10.1007/978-3-319-14160-2_2

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-14159-6

  • Online ISBN: 978-3-319-14160-2

  • eBook Packages: MedicineMedicine (R0)

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