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A Vesicular Site of Origin for the Release of a Cholinergic False Transmitter at the Torpedo Synapse

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Cholinergic Mechanisms

Part of the book series: Advances in Behavioral Biology ((ABBI,volume 25))

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Abstract

The morphological studies of Ceccarelli, Heuser (2,6) and others (for review see 14) have shown convincingly the increased occurrence of exocytotic profiles (of vesicles fusing with the presynaptic membrane) during induced activity at the neuromuscular function. Vesicle recycling is apparent from the inclusion of extracellular markers, observed in a number of tissues (5,11,15), but this does not necessarily prove that transmitter-containing vesicles undergo a similar process. Similarly, biochemical studies involving a comparison of the degree of radiolabelling of acetylcholine (ACh) in subcellular pools with that of stimulus-released transmitter, has also been subject to major difficulties of interpretation.

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References

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© 1981 Plenum Press, New York

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Luqmani, Y.A., Whittaker, V.P. (1981). A Vesicular Site of Origin for the Release of a Cholinergic False Transmitter at the Torpedo Synapse. In: Pepeu, G., Ladinsky, H. (eds) Cholinergic Mechanisms. Advances in Behavioral Biology, vol 25. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-8643-8_30

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  • DOI: https://doi.org/10.1007/978-1-4684-8643-8_30

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-8645-2

  • Online ISBN: 978-1-4684-8643-8

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